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of its programme—making out of london, over the next six years. a remarkable collection of handwritten letters from diana princess of wales to a friend are being sold at auction to raise money for arts charities. good afternoon and welcome to bbc news. ministers have sought to reassure people about the rollout of the coronavirus vaccine, amid a reduction in supply which means most people in their 40s will now have to wait till may for a jab. the government insists it will still offer all adults their first dose by the end ofjuly — but in the commons earlier today the health secretary confirmed supplies would become tighter in the weeks ahead. the bbc understands a delay in the delivery of 5 million doses of the oxford—astrazeneca jab from india is one factor. but matt hancock said no vaccine appointments booked would be cancelled and people would still get their second dose as planned. katharine da costa reports. this vaccination centre in south west london is one of hundreds around the country that so far help to give a dose to around half of all adults in england. having opened up appointments for the over 50s, the nhs in england is now being told not to offer vaccines to younger age groups throughout april because of supply issues. but the health secretary has insisted the roll—out will continue as planned. there will be no weeks in april with no first doses. there will be no cancelled appointments as a result of supply issues, second doses will go ahead as planned. most importantly, the vaccine data published yesterday showed the life—saving impact of this vaccine. it's not just that the vaccines are safe, it's that they make you safe. the uk had been expecting 10 million doses of the oxford astrazeneca vaccine from india this month, but only half has arrived. the serum institute has spoken of the pressure it's under. we are hoping very much that all other vaccine producers scale up because right now the pressure on serum institute is unprecedented. we are being tugged at by different governments in the world. we need to support astrazeneca. and we are being literally forced to supply as much product to the indian government as well. astrazeneca said its uk supply has not been affected. pfizer, which produces its vaccine in belgium, said deliveries to the nhs are also on track. and supplies of moderna are expected sometime in the spring. experts say the manufacture and supply of vaccines is a delicate process. of course, we are dealing with unprecedented demand. we are trying to get the same products to the whole world all at the same time, and supply chains have high quality characteristic so we do want these to be the highest quality out there. there is very strict testing and authorisations from the different health authorities. the government has warned uk supplies could be lumpy. you can see the supply can fluctuate from week to week. some of those advising the government on the roll—out are concerned delays could impact efforts to tackle the virus. phase two is really important, actually, and if we can't do that as spring progresses, we will be left in a position where we are continuing to have to have lockdowns and so on to control the spread of the virus. despite the setback, the government is still confident it can meet its target for offering all adults a jab by the end ofjuly. it said the road map for easing restrictions is still on track but it will no doubt come as a blow for the over 40s who will have to wait for their invite a little while longer. katharine da costa, bbc news. our correspondent in mumbai, nikhil inamdar, gave me more details about the situation in india regarding the supply of the astrazeneca vaccine. so far we haven't heard anything from astrazeneca on the specific shortfall in the uk. however, independent experts, or rather sources, have indicated that it was never a stipulated time line that was agreed upon by the serum institute, that in terms of supplies to the uk, and the delays are on account of higher domestic demand for the product given that we have seen a huge surge in cases. in fact, just today the indian external affairs minister very categorically saying that the overseas supply of vaccine will be completely dependent on domestic availability, and we have also been seeing some shortages in various parts of the country of the vaccine manufactured by the serum institute. india has also been seeing a huge surge and needs to step up its immunisation programme because we have had about 35,000 plus positive cases just in the last 2a hours, the highest since december. there's also been a second wave of sorts being reported in various provinces. india has a target to inoculate around 300 million people byjuly 2021 so the pressure to vaccinate is building up. let's get more from our political correspondent greg dawson. it was interesting listening to matt hancock at lunchtime because you got the sense that the government wants to try to reassure despite all the talk of a delay in some supplies. there was a lot of surprise at the downing street press conference yesterday that matt hancock did not tackle be letter from the nhs head—on but there was a change in tactic today in the commons. he stood up and mention it first and allay concerns of people about what this delay means in practical terms. he was keen to stress that if you have a vaccination appointment, it will not be cancelled, and that target of vaccinating everyone 50 and over will be met by the 15th of april, he said, and the target of vaccinating the whole adult population by the end ofjuly is still on course. he added that despite this delay, they seek the month of april is very much the month of april is very much the month to roll out second vaccinations and they are expecting to administer 12 million doses. matt hancock was keen to emphasise that when you go through a vaccination roll out on this enormous scale, there will be some problems with supply it here and there, but he did not anticipate it knocking the target of course. we did hear from the shadow health secretaryjonathan ashworth and he wanted to ask the health secretary if this would affect the government of�*s road map out of lockdown. but also he wanted the health secretary to acknowledge the health secretary to acknowledge the anxiety caused to some by the delay. many key workers under 50 like teachers — many key workers under 50 like teachers and police officers who threw _ teachers and police officers who threw the — teachers and police officers who threw the nature of their work are not threw the nature of their work are hot at _ threw the nature of their work are not at home and they are going out and they— not at home and they are going out and they are more exposed to risk of they had _ and they are more exposed to risk of they had been hoping that vaccination for them it was not far awax _ vaccination for them it was not far awax we — vaccination for them it was not far away. we understand why they will have to _ away. we understand why they will have to wait, because we understand, but this— have to wait, because we understand, but this hot— have to wait, because we understand, but this not fantastic news, and nor: _ but this not fantastic news, and nor, frankly, is it expected news. the home secretary said of course people will be disappointed but that the big picture is the government's target of everyone over 50 vaccinated by the 15th of april is still on target and that all adults should be vaccinated by the end of july and he was also keen to stress that this news does not knock the road map timetable. the government was very cautious in its timetabling of when we could emerge to some form of when we could emerge to some form of normality and he said this news does not delay that and he was also able to confirm the news that people who have been shielding, the clinically vulnerable for so long, they will be able to stop shielding from the end of march. greg dawson, thanks forjoining _ from the end of march. greg dawson, thanks forjoining us. _ this afternoon the prime minister will lead today's downing street briefing, he'll be joined by england's chief medical officer chris whitty and drjune raine from the medicines regulatory agency, the mhra. we'll have full coverage from 4.30 on bbc one and the bbc news channel. germany has seen a jump in the number of infections — it's just had its biggest daily rise in covid cases for nearly two months. it comes as the eu's medicines regulator is due to deliver its findings about the safety of the astrazeneca vaccine — its rollout has been halted across much of the eu because of concerns about blood clots. jenny hill reports from berlin. is germany playing it too safe? infection is spreading fast here, cases rising in newly reopened kindergartens. nursery workers have been pushed up the vaccination priority list. isabella and her staff were offered the astrazeneca jab. translation: i think it's devastating. - three of us were vaccinated on sunday, two others would have had it today, but that was cancelled. even if they re—approve it, my colleagues don't want to have it now. germany dismissed concerns about astrazeneca and blood clotting from other countries. it's used 1.6 million doses. but then it emerged seven people here have developed a rare type of blood clot on the brain within days of receiving the jab. experts say statistically they'd expect around one. the cases are deemed so severe — three people died — that the government argues it would be irresponsible not to pause the programme. translation: in my view, it's better if we suspend for a few days, - get a better view of the situation, and talk to our european partners. then we can say with certainty how we will proceed. some in germany weren't keen on astrazeneca in the first place, in part because the government initially blocked its use in older people. but this country, which has given just 8% of its population a first dose of vaccine, is relying on it. "there are always risks," he says. "you don't know how many people will die now "because they aren't vaccinated." she says, "they have got to check it. "the government is trying its best." the german government says this wasn't a political decision, and it's hard to see what the gain would be. more than 200 people are dying every day here from covid and public dissatisfaction is growing. ministers insist this was about inspiring trust. it may be they've achieved quite the opposite. jenny hill, bbc news, berlin. we have had more details coming through from jenny in berlin. in terms of cases of blood clot in germany, a couple more figures, because the country reporting an increase now in the number of people who have developed, who have developed a rare type of blood clot on the brain following having the astrazeneca job, on the brain following having the astrazenecajob, it on the brain following having the astrazeneca job, it says, according to the health ministry in berlin a total of 13 cases have been reported now. so 13 cases where someone has developed this rare type of blood clot on the brain, and all but one of those people where women, as it happens. and a wide age range. the 13 cases go from people aged 20—63 so a wide age range. 13 cases is what germany is now saying. the european regulatory agency is due to report more on that about the astrazeneca jab and may be in the next hour we will get much more. 0ur europe correspondent jean mackenzie is at the european medicines agency headquarters in amsterdam. she told us what to expect when we hear from the ema later this afternoon. yes, what they have been doing over the past few days is analysing each of these reported cases of blood clots, so that is fewer than 40, to see whether they can find a link between the vaccine and the clotting, so work out if it is a side—effect of the virus or is itjust a coincidence? they said on tuesday there was so far no indication the two were linked and urged countries to carry on using the vaccine. we are expecting later today for them to give a finaljudgment on how likely it is this vaccine increases the risk of clotting, and so therefore, are the risks, are the benefits still greater than the risk given that we know this is a vaccine that is saving lives every single day? countries really desperately struggling in europe to vaccinate people fast enough as they battle what appears to be the onset of another wave of this virus. the fear is the suspension might have put people off having the vaccine, that is something they cannot afford at the moment. countries say they were being cautious, that they wanted to be absolutely sure this vaccine was safe, but certainly there are those who are questioning if they should have waited for the evidence later today before they pressed pause. jean mackenzie in amsterdam. we are keeping a close eye on that and as soon as we get any comments we will bring them to you. we think sometime after three o'clock. nhs chief executive sir simon stevens said he was "personally delighted" as he received his first covid—19 vaccine jab. sir simon, who's 5a, said the oxford astrazeneca jab which he received at westminster abbey's vaccination site was "quick, painless and effective". todayis today is another huge milestone in the nhs covid vaccination programme because by the end of today over half of adults in this country would have had their vaccine. as a 54—year—old i was pleased to get my invitation yesterday, to have my 0xford astrazeneca jab this morning, and i have to tell you it was quick and i have to tell you it was quick and painless. and effective. so we are well on track to make sure that everybody aged 50 and over can be offered their vaccine well ahead of the 15th of april goal, so the suggestion is if you are invited, please step forward and take up the offer. the headlines on bbc news... health secretary matt hancock says covid vaccination targets will still be met for the nine priority groups, despite a drop in vaccine supply in april. the care regulator says hundreds of patients had "do not resuscitate" notices put on them at the start of the pandemic without their knowledge. the bbc announces major plans to move large parts of its programme—making out of london, over the next six years. the care regulator for england has said hundreds of people had their human rights breached when "do not resuscitate" decisions were placed on them during the early part of the pandemic — without them or their families knowing about it. a report by the care quality commission says there's some evidence that blanket dnr decisions — which restrict potentially life—saving treatment — were used on elderly and disabled people. nikki fox reports. hi, everyone, i'm jordan. jordan is supported by dimensions. this is my support worker, emma. hi. we're currently making an omelette. his social care provider is one of many who have fought to remove inappropriate "do not resuscitate" orders during the pandemic. i want me and my friends to grow old and have a happy and fulfilling life, and to have these decisions made for us, against us, in this way i think is very inhumane. it did create a real climate of fear, i think, amongst people with learning disabilities and their families about what the outcomes might be for people. for the "do not resuscitate" orders that you'd heard about, the inappropriate ones, rachel, what were some of the reasons given? we had somebody we support and the reason given for their order was that they had dyspraxia, asthma and a learning disability, which is clearly entirely inappropriate reasons to apply a "do not resuscitate" order. and there are many examples of this. in fact, the care quality commission was told of more than 500 cases where a "do not resuscitate" order was applied without the consent of the person or their family. it said it raised serious concerns that many disabled people were seeing their human rights breached by not being given the right to choose their own end—of—life care. we know at the beginning of the pandemic there - was a lot of confusion. i think some of that confusion - and some of the miscommunication did lead to this increase in dnr cpr decisions that we saw. - it's completely unacceptable. it'sjust terrifying. your life is everything you own, so, scary. sarah, who wants us to protect her identity, has a rare neuromuscular condition. she's in her early 20s and is a successful writer. at the beginning of the pandemic she was asked on three occasions to sign a "do not resuscitate" order. there was no back—and—forth, it was very much, "i think this should happen to you," it was just, "i think this is best." "they wouldn't treat you anyway, let's do it." it was a tick box exercise. i think of a 20—year—old me, i would have been useless at that conversation. i mean, i have had practice, like, i do use a hospice, but this has felt different. this has felt like a fight, which i really don't enjoy. the government says it would take on board the report's recommendations and stressed that blanket "do not resuscitate" orders were always completely unacceptable. nikki fox, bbc news. the health secretary matt hancock has announced more than £6 billion for the nhs in england, partly to deal with waiting lists. earlier today, nhs providers, representing hospitals and other trusts in england, said that clearing the backlog of non urgent operations will take years rather than months. recent figures showed that more 300,000 patients in england had waited more than a year for routine surgery. our health editor hugh pym talked this morning to the chief executive of a leading hospital and told me what he had to say. professor marcel leavy is chief executive of university college london hospitals trust. he came over to london from the netherlands, where he had an eminent medical career four years ago to take on the role of running the hospital and he goes back to the netherlands at the end of this month to become the dutch government's chief scientific adviser, so his take on the pandemic and the state of the nhs is very, very interesting. a key point he made about these long waits for non—urgent surgery is the nhs already had long waiting lifts before the pandemic and covid was a magnifying glass for that problem because of the cancellations which have creaed a longer series of waits for people. here's what he had to say on what can be done about that. it's going to take, i'm afraid, a very long time to get where we want to be, at least a year and probably longer. does it need more moneyjust to get through these procedures, doing extra hours and weekends and so on? yes, of course it will take more money and of course we will try to do this as efficient as possible, but you can only treat all those patients if you introduce even more weekend working, evening working, extra shifts, extra operating theatre time. of course that will take a little bit of money. and he was extremely complimentary about the nhs and staff. he paid tribute to those he had worked with and he made a very interesting comment about the nhs�*s role during the pandemic, that it had been involved in some successes, whereas less successful programmes were done by others. everything that has been a success was actually the part that was done by the nhs. everything that was actually not so successful, i'm talking about test and trace, i'm talking about ppe provision, all these things, were actually the things that had to be outsourced to companies that failed in what they promised to deliver, so that's a reminder for the future. professor marcel levi speaking to me. matt hancock has just announced new money for the nhs in england for the first half of the upcoming financial year partly to deal with bringing down these long waiting lists and we will have to await reaction from health leaders as to whether that £6.6 billion is going to be enough. the inquest into the death of sarah everard has been opened, and adjourned until the end of the trial of the man accused of her murder. 0ur correspondent charlotte wright was at the coroners court in maidstone. it took just under it tookjust under half an hour for the inquest to be opened and adjourned today. sarah's mother, father, brotherand adjourned today. sarah's mother, father, brother and sister were watching remotely via video link and we'd heard from the acting detective inspector from the met who is working on the case who went to some the details that we note surrounding sarah's disappearance. we know she was having dinner with a friend in clapham two weeks ago before she disappeared on her walk home and it was her boyfriend who raised the alarm the next day, concerned about her whereabouts. of course her body was then discovered the following week last week in an area of woodland just outside ashford in kent. two postmortem examinations have now taken place but today they did not give a medical cause of death. we were told of her body has been given back to herfamily, though, as they continue with the funeral arrangements. a serving met police officer has been charged with her kidnap and murder. a provisional date for the trial has been set for the 25th of october. of course the inquest won't continue until the criminal proceedings have taken place. adjourning today the coroner said all that remains to be said to sarah's family isjust said all that remains to be said to sarah's family is just how sorry she is for their loss. bt has confirmed plans to spend £12 billion rolling out full fibre broadband to 20 million homes in the uk by the end of the decade. the announcement follows 0fcom's decision to allow bt 0penreach to charge companies more for using its fast fibre network, to encourage it to invest in the infrastructure's rollout. speaking to the bbc, the chief exeuctive of 0fcom explained their plan. the government's target is to reach 50 million homes by the middle of the decade and what we are doing today will really support that because it incentivises people to come and build in the private sector, and we think that we can reach 70% of homes over the next few years with more than one network to choose from, so it is very complimentary. lots more to talk about in the next half an hour including plenty more around vaccines and delays and also new figures out in germany, so we will be talking much more about all of that in the next half an hour. now it's time for a look at the weather with tomasz. very little happening on the weather front across the uk in the coming days. it will essentially stay more or less the same from day to day. there will be a bit of sunshine developing but on the whole pretty cloudy. 0n the satellite picture you can see where the clouds are coming from, drifting in from the norwegian sea, riding around this area of high pressure which is parked to the west, south—west of ireland, and this is where the high pressure is more or less going to stay over the next few days and you can see the air currents, the wind blowing around, so the cloud is coming in from the north but it tends to break up. in some areas it is thick enough to produce rain and we have had rain in the last day or so and there could be more damp weather anywhere from eastern parts of england through the east midlands and into the south—east. frost free for most, perhaps a touch of frost where sky is clear in the coming days. notice tomorrow, a definitive edge between dry and sunny weather coming in from the continent and this thick cloud across the rest of the country so the thinking is from hull down into london and southampton, sunshine developing on friday afternoon. somewhat drier air heading our way. high pressure is still with us on saturday and saturday is the first day of astronomical spring by the way, the vernal equinox, so we are well and truly into spring, but the weather is not changing much. wind still blowing out of the north out of scotland and may be a spot of rain forced all the way, but of the country it is a case of variable amounts of cloud and the high pressure is still with us through the weekend into next week, thejet stream is way to the north sending the unsettled weather in the direction of iceland, and also around the mediterranean, but we are closer to the high so little change. take a look at the outlook for the next few days. the weather icons indicating just clouds, variable amounts of cloud, difficult to indicate, with temperatures hovering between 11—13. the weather will change but not until later next week. goodbye. hello, this is bbc news with jane hill. the headlines: the health secretary says all adults in the uk will get their first covid jab by the end ofjuly, despite a drop in vaccine supply in april. the european medicines agency prepares to deliver its decision about the safety of the astrazeneca jab, after many eu countries paused its rollout. the care regulator says huundreds of patients had "do not resuscitate" notices put on them the start of the pandemic without their knowledge. the bbc announces major plans to move large parts of its programme—making out of london, over the next six years. a remarkable collection of handwritten letters from diana princess of wales to friend are being sold at auction to raise money for arts charities. sport now and let's get a full round up from the bbc sport centre. good afternoon. first to ahmedabad in gujarat where england can win their t20 series against india today. looking to take an unassailable 3—1 lead, eoin morgan's named an unchanged eleven. england won the toss and have, as expected, chosen to bowl. so far in this series the team batting second has won the match, so india have it all to do. they are 87—3 now. rohit removed byjofra archer for 12, india faltering. virat kohli's gone for1 thanks to adil rashid, but it's suryakumar yadav, in his first international knock, who's been explosive. the icc�*s player of the decade, australia all—rounder ellyse perry, is the latest recuit for this summers hundred competition, which starts on the 21st ofjuly after a year—long delay because of covid—19. she's joined birmingham phoenix. perry's won five t20 world cups and says she's looking forward to the challenge of a brand new contest. it's always a special moment in time in a sport when something like this comes along. to have the opportunity to be a part of it and experience it when it first starts, i think it's a little bit similar to when the wbbl started in australia and i feel very chuffed that another country wanted me to come and play for them. it'll be great for all of us. aston villa striker 0llie watkins and west brom goalkeeper samjohnstone have been given their first senior england call—ups, as gareth southgate names his squad for the 2022 world cup qualifiers. jesse lingard, john stones and luke shaw return but here's no place for liverpool defender trent alexander—arnold. villa striker watkins gets his first senior england call up after impressing since joining from brentford in the the summer. west brom goalkeeper sam johnstone also gets a first call up following an injury to england number onejordan pickford. southgate's named a 26—man squad for the qualification triple header against san marino, albania and poland this month. paddy mcnair has been included in the northern ireland squad for next week's world cup qualifiers, despite concerns over his fitness. he was forced off with a knee problem in middlesbrough's win over preston in the championship on tuesday night but he still makes the 26—strong international party. they're away to italy on the 25th, and at home to bulgaria six days later. there was a big shock in the first race on the penultimate day of the cheltenham festival — the novices' chase. the odds on favourite envoi allen fell early on, leaving nico de boinville to ride the 8—1 shot chantry house to victory. that's a historic moment for nicky henderson. he's the first uk trainer to reach 70 winners at cheltenham. now to the six nations, and lock adam beard is back in the side for wales's bid to complete a six nations grand slam on saturday when they face france in paris. he was rested for last weekend's win over italy, after starting in their three previous victories. he'll partner captain alun wynjones in the second row. that's coach wayne pivac�*s only change to the line—up. just one change for england too, for their match against ireland in dublin. elliot daly will start at outside—centre for the first time in almost five years, replacing the injured henry slade. daly returns after he was relegated to the bench for the win over france last weekend, with max malins starting at number 15. that's all the sport for now. a small number of cases but they say they are concerned and lets talk more about that and what it might mean in this country because our health correspondence joins me. germany has put out some figures around this whole issue of blood clotting and you have just come out of a briefing here in terms of what this might mean in the uk. yes. as well as of the _ this might mean in the uk. yes. as well as of the european _ this might mean in the uk. yes. as well as of the european medicines l well as of the european medicines regulator looking at this issue the uk regulator has also been reviewing vaccinations given in the uk. they have been looking out over 10 million astra—zeneca vaccinations and they have identified five cases of this rare blood clot which is what the european regulator is looking at. these five cases are aged 19 to 59. one of the individuals unfortunately did die. but as i say, this is out of more than 10 million doses so this is very rare. the first thing regulators do is to look at how many cases would be expected in the general population to see if the numbers after vaccination a higher and what you would normally expect. so is it a coincidence or the cause. but because this type of blood clot in the brain is so rare it is difficult to say whether those five cases are above what you would normally expect. so they will carry out more investigations into the cases. they say there is nothing at this stage to suggest the vaccine has caused it. in fact, covid itself would raise the risk of this rare blood clot. 0ne would raise the risk of this rare blood clot. one of the things they are looking at is whether these individuals had covid at the time. the key message is that the vaccination is safe and the benefits outweigh any of the small risks. they point out that these five cases, more than 10 million people vaccinated, that's one case for every 2 million vaccinations so even someone in their 40s, if they catch covid they have a one in 1000 chance of dying. so you can see the benefits and the risks. and of dying. so you can see the benefits and the risks. and worth reiteratin: benefits and the risks. and worth reiterating the _ benefits and the risks. and worth reiterating the numbers. - benefits and the risks. and worth reiterating the numbers. they . benefits and the risks. and worth l reiterating the numbers. they have been five cases in this country but thatis been five cases in this country but that is out of more than 10 million doses administered or 10 million people who have had a vaccination. i'm interested that you mentioned the ages and do we know whether the five cases where people with underlying conditions because if you are talking about someone who is only 19 or 20 having a vaccine, healthy 19—year—old isn't eligible for a vaccine at the moment so is it a fair assumption that they would have had other issues? that a fair assumption that they would have had other issues?— a fair assumption that they would have had other issues? that was one ofthe have had other issues? that was one of the questions _ have had other issues? that was one of the questions we _ have had other issues? that was one of the questions we asked _ have had other issues? that was one of the questions we asked at - have had other issues? that was one of the questions we asked at the - of the questions we asked at the briefing. they have not identified if they have got health conditions so yes they could be part of that younger cohort who because they have health conditions have been vaccinated first. they could be care workers as well. they could have got the vaccine for that reason. they do need more time to properly investigate them but they are adamant that this should not necessitate a pause to the programme like has happened in europe. the vaccine is completely safe and because of the risks covid presents, evenif because of the risks covid presents, even if a risk is proven here, evaluate —— effect is proven here, it still wouldn't stop the vaccination programme because the vaccination programme because the vaccination programme because the vaccination programme saving lives. and there is a member ten briefing coming up later so you can imagine they will be plenty of questions about this and when we reflect on everything matt hancock said at lunchtime you could feel i think he was keen to reassure people that things were on track even though we have been reflecting off course on the delays to supplies. yes. the delays to supplies. yes, su lies the delays to supplies. yes, sunplies has _ the delays to supplies. yes, supplies has been _ the delays to supplies. yes, supplies has been a - the delays to supplies. yes, supplies has been a big - the delays to supplies. yes, | supplies has been a big focus the delays to supplies. 1913 supplies has been a big focus this morning. the government is adamant it will meet the target of offering all adults vaccination by the end of july. the over 50s should be complete by mid april. there is some hope that they will get the vaccine or the offer of the vaccine by the end of the month. but they had been hope that the roll—out would happen more quickly than even the government had anticipated. what we have heard over the last 2a hours is that some supplies from india haven't arrived as quickly as was hoped and that means the speed at which we can do the roll—out from april onwards is a bit slower than we expected at the start of the week but the government says the targets will still be met.— will still be met. thank you very much. will still be met. thank you very much- that _ will still be met. thank you very much. that number _ will still be met. thank you very much. that number ten - will still be met. thank you very much. that number ten briefing| much. that number ten briefing coming up a little later on this afternoon and we will have full coverage from four —— liz30pm. the operators of drayton manor theme park have been fined £1 million for safety failings which led to the death of an 11 year old girl in 2017. evha jannath from leicester, and who could not swim, died after she fell from the splash canyon water rapids ride, while on a school trip. thejudge said her death was �*an utterly tragic waste of a young life.�* people seeking asylum in the uk could be sent abroad while their cases are being processed. it's thought the proposals are part of a major shake—up of the immigration system to be announced by the home secretary, priti patel, next week. similar plans were leaked last year when labour described them as inhumane and impractical. many newspapers have been speculating where they could be sent. 0ur chief political correspondent adam fleming said we wouldn't know what the government was hoping to do until their plans are announced next week. i think that is just a bit of speculation. we'll have to wait until this proposal we get next week to get a bit more detail and even then we might not get that much more detail because i think they are saving all of that for the sovereign borders bill which will be the giant, monster piece of legislation that will reform the asylum system, which i'm told is going to be a centrepiece of the queen's speech, which we are expecting in may, so this will be a big, huge, dominating issue for the next session of parliament and i think it will be one of the big stories for the next few years. you talk about how it's been speculated upon since last year. actually, it was tony blair that first proposed this 18 years ago, which gives you a bit of an idea about how long changes of this magnitude actually take to introduce. "the border is secure, the border is not open." the words of president biden�*s homeland security chief in response to the surge in migrants attempting to cross from mexico. recent weeks have seen an increase in arrivals with many believing the new adminstration will ease the rules. in february alone, 100,000 people were arrested at the border between the united states and mexico. 9,500 of those were children. that's a 28% increase onjanuary and the numbers are expected to rise further. migrants often come from central america, making the dangerous journey through mexico on foot. the bbc�*s marcos gonzales travelled with a family from honduras and has this exclusive report. this family from honduras has been walking for three days trying to reach the united states and they have only crossed into mexico. they lost their home because of hurricane and gangs asked for money to leave them alone. with no money, she is making her —— the long journey with her family. after a slow down because of the pandemic thousands of migrants from central america and are travelling again. there is shelterfor instance received more people in the first two months of this year than in all of 2020. there's shelter in mexico is one of the stops on the migrant route but because of the increase in the arrival of people this year for shelter cannot accept all the people waiting here every single day. 0utside waiting here every single day. outside the shelter we meet this man was 17 and has been walking from honduras for five days. he walked hundreds of kilometres with these worn out shoes but he believes that travelling without his parents will help them enter the united states. in the middle of the night we found this family again. but for them, staying at home in honduras is even more dangerous. the next morning and with little water they resumed theirjourney. water they resumed their journey. they water they resumed theirjourney. they are crossing mexico on foot, a journey that can take up to 30 days. they are exhausted, hungry and afraid of getting arrested. six hours later, the walk has been a real challenge. michael has no regrets but he has a message for those planning to make this trip. michael will probably walk all night until the next shelter. he still has a few weeks ahead to reach the border. looking for his american dream. the bank of england has kept interest rates on hold as it said the rapid rollout of the vaccination programme and road map for easing restrictions would help drive an economic rebound this year. the bank said the prime minister's plans would see england brought out of lockdown faster than it expected, helping to deliver a "slightly stronger" rise in consumer spending than it previously predicted. we can speak now to our business correspondent vishala sri—pathma it wasn't as upbeat as some are commonest were expecting. i'm joined now by karen ward from... there commonest were expecting. i'm “oined now by karen ward from. . .* now by karen ward from... there are two reasons. — now by karen ward from... there are two reasons, there _ now by karen ward from... there are two reasons, there are _ now by karen ward from... there are two reasons, there are uncertaintiesl two reasons, there are uncertainties about— two reasons, there are uncertainties about the _ two reasons, there are uncertainties about the recovery and one of them is that— about the recovery and one of them is that households have a lot of savings — is that households have a lot of savings they have accumulated over the last _ savings they have accumulated over the last year as they haven't been able to— the last year as they haven't been able to go— the last year as they haven't been able to go out and spend and it's a realty— able to go out and spend and it's a really big — able to go out and spend and it's a really big number. it's at least 8% of gdp _ really big number. it's at least 8% of gdp. but we just don't know how quickly— of gdp. but we just don't know how quickly or— of gdp. but we just don't know how quickly or whether they're going to id quickly or whether they're going to go out _ quickly or whether they're going to go out and — quickly or whether they're going to go out and spend that money. so in the second — go out and spend that money. so in the second half of the year we could have a _ the second half of the year we could have a phenomenal bounce back an activity— have a phenomenal bounce back an activity and — have a phenomenal bounce back an activity and a really strong recovery— activity and a really strong recovery as the money gets spent. alternatively, households could remain — alternatively, households could remain cautious. we also have uncertainty about the international positiorx _ uncertainty about the international position. it looks like the us realty— position. it looks like the us really is _ position. it looks like the us really is going to boom open. they have a _ really is going to boom open. they have a big — really is going to boom open. they have a big fiscal stimulus under way _ have a big fiscal stimulus under way but— have a big fiscal stimulus under way. but you would have's vaccination programme isn't going so well. vaccination programme isn't going so wett 50— vaccination programme isn't going so wett so not— vaccination programme isn't going so well. so not really surprised they emphasise the uncertainty but there is a market— emphasise the uncertainty but there is a market angle to this and the markets — is a market angle to this and the markets are starting to get concerned about the central bank's taking _ concerned about the central bank's taking away that punchbowl and that stimulus _ taking away that punchbowl and that stimulus to early so they are not going _ stimulus to early so they are not going to — stimulus to early so they are not going to frighten the horses in the near term — going to frighten the horses in the nearterm. in going to frighten the horses in the near term. . going to frighten the horses in the near term. , ., ., �* near term. in terms of trade, we've had data in — near term. in terms of trade, we've had data in the _ near term. in terms of trade, we've had data in the last _ near term. in terms of trade, we've had data in the last few— near term. in terms of trade, we've had data in the last few weeks - near term. in terms of trade, we've | had data in the last few weeks about a drop in exports from the uk to the eu. do you think that something that is to be concerned about going forward? i is to be concerned about going forward? ~' ., is to be concerned about going forward? ,, ., ., ., , forward? i think for a few reasons. there was — forward? i think for a few reasons. there was an _ forward? i think for a few reasons. there was an extremely _ forward? i think for a few reasons. there was an extremely large - forward? i think for a few reasons. there was an extremely large drop forward? i think for a few reasons. i there was an extremely large drop to the eu _ there was an extremely large drop to the eu and _ there was an extremely large drop to the eu and we know we are going through— the eu and we know we are going through the brexit deal and there is a lot through the brexit deal and there is a tot of— through the brexit deal and there is a lot of uncertainty. many businesses are coping with the new customs _ businesses are coping with the new customs regime. sol businesses are coping with the new customs regime. so i think there is a question— customs regime. so i think there is a question as to how temporary that is and _ a question as to how temporary that is and whether as companies get used to the _ is and whether as companies get used to the new— is and whether as companies get used to the new systems that restores, whether _ to the new systems that restores, whether it's a longer lasting issue. for the _ whether it's a longer lasting issue. for the outlook i think where this is particularly relevant and concerning his with regards to ihfiatioh _ concerning his with regards to inflation. if we get a really strong houhce _ inflation. if we get a really strong bounce back in demand as households rush out— bounce back in demand as households rush out to _ bounce back in demand as households rush out to spend all that money as i rush out to spend all that money as i described — rush out to spend all that money as i described but they get to the shops— i described but they get to the shops and there is nothing on the shelves _ shops and there is nothing on the shelves because we couldn't get the goods— shelves because we couldn't get the goods in. _ shelves because we couldn't get the goods in, that is where we have an inflation _ goods in, that is where we have an inflation concern. find goods in, that is where we have an inflation concern.— goods in, that is where we have an inflation concern. and one question on inflation- — inflation concern. and one question on inflation. given _ inflation concern. and one question on inflation. given the _ inflation concern. and one question on inflation. given the way - inflation concern. and one question on inflation. given the way interest| on inflation. given the way interest rates are and where the economy is, are we likely to see that move at all if inflation does that to increase?— all if inflation does that to increase? , , , , ., , increase? this is probably temporary and therefore _ increase? this is probably temporary and therefore we _ increase? this is probably temporary and therefore we shouldn't _ increase? this is probably temporary and therefore we shouldn't take - increase? this is probably temporary and therefore we shouldn't take too | and therefore we shouldn't take too much _ and therefore we shouldn't take too much attention to it. i think the inclination— much attention to it. i think the inclination would be to let the economy— inclination would be to let the economy run and let it gather steam and help— economy run and let it gather steam and help the government pay back some _ and help the government pay back some debt and help companies pay back some — some debt and help companies pay back some debt. but of course as it goes _ back some debt. but of course as it goes from — back some debt. but of course as it goes from one to two hot that is when _ goes from one to two hot that is when perhaps the bank of england would _ when perhaps the bank of england would have to react. but we're probably— would have to react. but we're probably not talking about the next orso probably not talking about the next or so at _ probably not talking about the next or so at least. i probably not talking about the next or so at least.— or so at least. i am sure we will be talkin: or so at least. i am sure we will be talking about _ or so at least. i am sure we will be talking about the _ or so at least. i am sure we will be talking about the outlook - or so at least. i am sure we will be talking about the outlook for - or so at least. i am sure we will be talking about the outlook for cyberj talking about the outlook for cyber time. thank you. one of the defining moments of last year's black lives matter protests was the statue of slave trader edward colston being torn down in bristol. it started a national debate about how the uk remembers the darker parts of its history. the debate about what to do with statues of slave traders is continuing, but what about schools with links to controversial historical figures? pupils at a primary school in bristol have helped to design a new logo because the old one was the family crest of edward colston, whose statue was toppled during the black lives matter protests last year. our community affairs correspondent adina campbell reports. one of the defining moments of last year's black lives matter protests was the statue of slave trader edward colston being torn down in bristol. it started a national debate about how the uk remembers the darker parts of its history. the dolphin school in bristol has been exploring its own links to edward colston. the logo is edward colston's, like, family crest. he was responsible for a lot of the slave trade. we discussed about how the school logo needed to be changed. - post— the kind of colston statue in bristol being toppled, we looked at why the school was named the dolphin school, what the history behind the crest was. legend has it that a dolphin prevented one of colston's ships from sinking. the students have been working with a local artist to create a new school logo. when i understood the story of and the connection between colston and the dolphins, and i could the symbolism within that current emblem, so i took that idea back to the children and asked them what they would want to see the new emblem represent — and it was all around diversity, equality. they designed four potential emblems. they were mostly based around, like, our world and how diverse it is, and dolphins. and rather than being remembered as what edward colston founded, being remembered as a really diverse curriculum. changing the name of the school was also discussed. the decision was to keep the name of the school but to change the emblem because that's where they felt that that was the closest links to the edward colstons and we were really proud of the way the children talked about this — so they could see the historical elements — but they were also saying, "but we really like the name "the dolphin school" because it's a dolphin and we love dolphins as curious animals, and we think they represent the diversity in the oceans, as well." this design was finally chosen to be the new school logo. i don't believe in erasing history. i mean, what has happened has happened and we can acknowledge it and we can learn from it and we can move forward and hopefully not make the same mistakes again. and i felt it was the right move to make by still incorporating a dolphin, by not changing the school's name — butjust by giving it a bit of a refresh. adina campbell, bbc news. a collection of letters written by diana, princess of wales, will be sold at auction today. they were sent to a close family friend during the 1990s — and the money raised will go towards arts charities that diana supported. sarah ransome has the details. (tx) from farmhouse cupboard to auction house strongroom. for more than 20 years, roger bramble has kept safe these personal letters and cards from diana, princess of wales. he was a close family friend, and this correspondence has remained untouched and private, but is now about to become public. it was a little bit like christmas. it was a real sort of treasure trove. for the auction house, helping this royal collection go public was a privilege. i get a sense of a real continuity, you know, she stayed a warm, loyal, affectionate person, no matter what else was going on, and obviously we know that period was a period of enormous turmoil in her life. her relationship with roger, who they were written to, obviously was a constant. written in the 1990s, some thank her friend for champagne lunches and trips to the ballet. 0thers hint at more turbulent times. as diana's marriage broke down, and media scrutiny intensified, having people to trust became increasingly important. i think it meant a lot to her to stay in touch with people she really cared about, and she opened up to roger about lucia flecha de lima, for example, who was a woman who was close to her mother's age. a small number of friends were absolutely key, probably to her sanity, actually. archive news report: most of the newlyn fleet was in for today's event. whether it were fishing boats, orfactories, diana's charisma went before her. whenever princess diana came to places like this, crowds would gather wherever she went. she came here, to newlyn, to open the new fish market in 1988, and that star quality, that appeal, seems to shine as bright as ever. the auction house says they've had interest in the letters from all over the world. the sale is expected to reach upwards of £30,000, with the proceeds going to organisations close to diana's heart. after reading these, i warmed to her enormously. i think she probably was a lovely person, and i sort of think, oh, she would have been a lovely person to go outwith, to go to one of these wonderful lunches, or something. i think, yeah, it has changed my opinion quite a lot. for the owner, it's not about the money, but the glimpse the letters give into the private world of a princess, who lived so much of her life in the spotlight. sarah ransome, bbc news, penzance. now it's time for a look at the weather with tomasz. hello. there's very little happening on the weather front across the uk in the coming days. it's going to essentially stay more or less the same from day—to—day. there will be a little bit of sunshine developing, but on the whole, pretty cloudy. on the satellite picture, you can see where the clouds are coming from. they are drifting in from the norwegian sea, riding around this area of high pressure which is parked to the west, southwest of ireland and this is where the high pressure is more or less going to stay over the next few days. you can see the air currents, the wind blowing around the higher, hence the cloud is coming in from the north, but it tends to break up in a few areas. but in other areas, it is thick enough to produce rain. we've had rain in the last day or so. there could be more damp weather anywhere from eastern parts of england, through the east midlands and into the southeast as well, but frost—free for most of us, perhaps a touch of frost where the sky is clear in the coming days. notice tomorrow there is a very definitive edge between drier, sunnier weather coming in out of the continent and this thicker cloud across the rest of the country. the thinking is from hull to london and southampton there will be sunshine developing on friday afternoon, somewhat drier air heading our way, evaporating the clouds. the high pressure's still with us on saturday, which is the first day of astronomical spring, the vernal equinox, so we well and truly are into spring, but the weather isn't changing much. the wind still blowing out of the north across scotland, perhaps a spot of rain for stornoway. for the rest of the country, it's a case of variable amounts of cloud and this high pressure is still with us through the weekend into next week. the jet stream is way to the north of us, sending the unsettled weather in the direction of iceland and also around the mediterranean, but we're closer to that high. so little change and take a look at this outlook for the next few days. the weather icons indicating clouds or variable amounts of cloud — very difficult to actually indicate on a symbol — with temperatures hovering between 11—13 celsius. the weather will change, but not until later next week. that's it from me. bye— bye. this is bbc news. i'm jane hill. the headlines... the health secretary says covid vaccination targets will still be met for the nine priority groups, despite a drop in vaccine supply in april. there will be no weeks in april with no first doses. there will be no cancelled appointments as a result of supply issues. second doses will go ahead as planned. the european medicines agency prepares to deliver its decision about the safety of the astrazeneca jab, after many eu countries paused its rollout. the care regulator says hundreds of patients had "do not resuscitate" notices placed on them at the start of the pandemic — without their knowledge. the bbc announces major plans to move large parts of its programme—making out of london, over the next six years. a remarkable collection of handwritten letters from diana princess of wales to a friend are being sold at auction — to raise money for arts charities. good afternoon and welcome to bbc news. ministers have sought to reassure people about the rollout of the coronavirus vaccine, amid a reduction in supply which means most people in their 40s will now have to wait till may for a jab. the government insists it will still offer all adults their first dose by the end ofjuly — but in the commons earlier today the health secretary confirmed supplies would become tighter in the weeks ahead. the bbc understands a delay in the delivery of 5 million doses of the oxford—astrazeneca jab from india is one factor. but matt hancock said no vaccine appointments booked would be cancelled and people would still get their second dose as planned. katharine da costa reports. this vaccination centre in south west london is one of hundreds around the country that so far help to give a dose to around half of all adults in england. having opened up appointments for the over 50s, the nhs in england is now being told not to offer vaccines to younger age groups throughout april because of significant supply issues. but the health secretary has insisted the roll—out will continue as planned. there will be no weeks in april with no first doses. there will be no cancelled appointments as a result of supply issues, second doses will go ahead as planned. most importantly, the vaccine data published yesterday showed the life—saving impact of this vaccine. it's not just that the vaccines are safe, it's that they make you safe. the uk had been expecting 10 million doses of the oxford astrazeneca vaccine from india this month, but only half has arrived. the serum institute has spoken of the pressure it's under. to provide both international and domestic supplies. we are hoping very much that all other vaccine producers scale up because right now the pressure on serum institute is unprecedented. we're being tugged at by different governments in the world. we need to support astrazeneca. for the countries they need to supply vaccines too. and we are being literally forced to supply as much product to the indian government as well. astrazeneca said its uk supply has not been affected. pfizer, which produces its vaccine in belgium, said deliveries to the nhs are also on track. and supplies of moderna are expected some time in the spring. but experts say the manufacture and supply of vaccines is a delicate process. of course, we're dealing with unprecedented demand. we are trying to get the same products to the whole world all at the same time, and these supply chains have high quality characteristic so we do want these to be the highest quality out there. there is very strict testing and authorisations from the different health authorities. the government's warned uk supplies could be lumpy. you can see the supply of doses can fluctuate from week to week. some of those advising the government on the roll—out are concerned delays could impact efforts to tackle the virus. phase two is really important, actually, and if we can't do that as spring progresses, we will be left in a position where we are continuing to have to have lockdowns and so on to control the spread of the virus. despite the setback, the government is still confident it can meet its target for offering all adults a jab by the end ofjuly. it says the road map for easing restrictions is still on track but it will no doubt come as a blow for the over 40s who will have katharine da costa, bbc news. our correspondent in mumbai, nikhil inamdar, gave me more details about the situation in india regarding the supply of the astrazeneca vaccine. so far we haven't heard anything from astrazeneca on the specific shortfall in the uk. however, independent experts, or rather sources, have indicated to us that it was never a stipulated time line that was agreed upon by the serum institute, in terms of supplies to the uk, and the delays are on account of higher domestic demand for the product given that we have seen a huge surge in cases. very categorically saying that the overseas supply of vaccine will be completely dependent on domestic availability, and we have also been seeing some shortages in various parts of the country of the vaccine manufactured by the serum institute. india has also been seeing a huge surge and needs to step up its immunisation programme because we have had about 35,000 plus positive cases just in the last 2a hours, the highest since december. there's also been a second wave of sorts being reported in various provinces. india has a target to inoculate around 300 million people byjuly 2021 so the pressure to vaccinate is building up. let's get more from our political correspondent greg dawson. the government still very much trying to talk about reassurance despite some supply problems. yes. despite some supply problems. yes, matt hancock — despite some supply problems. yes, matt hancock the _ despite some supply problems. use: matt hancock the health secretary was on the floor of the house of commons earlier and it was his mission today to try and allay concerns about the implications of this delay in the vaccination roll—out. he was very keen to stress that if you have a vaccination appointment, it won't be cancelled, and that all the over 50s will still be vaccinated by the government target date of the 15th of april, and that the entire adult population will have the offer of a vaccination by the end ofjuly. he stressed that the cause when you have huge the cause when you have a huge vaccination roll—out programme on vaccination roll—out press rs some an enormous vaccination roll—cut programmes-rt enormous scale, vaccination roll—out programmeon enormous scale, there will vaccination roll—out programmeon enorr be, scale, there will vaccination roll—out programmeon enorr be, he ale, there will vaccination roll—out programmeon enorr be, he said, 1ere will vaccination roll—out programmeon enorr be, he said, be 3 will vaccination roll—out programmeon enorr be, he said, be some inevitably be, he said, be some delays and in the road, a delays and lumps in the road, a lumpy process, i think he called it, but then we heard from the shadow health secretaryjonathan ashworth health secretary jonathan ashworth who health secretaryjonathan ashworth who wanted to check if this delay potentially would affect the government's road map out of lockdown and he wanted matt hancock to address the anxieties of those who will be potentially affected by these delays. many key workers under 50 like teachers and police officers who through the nature of their work are not at home and they are going out and they are more exposed to risk, had been hoping that vaccination for them it was not far away. we understand why they will have to wait, because we understand, but this not fantastic news, and nor, frankly, is it expected news. the government says they need to look at the bigger target, to have offered adults a vaccination by offered all adults a vaccination by the end ofjuly. in terms of the lockdown and the road map out of it, the government has been cautious in terms of the timeline, but they have said these delays have no impact on road map out, and the health the road map out, and the health secretary was also keen to confirm the news yesterday that people who are clinically vulnerable who have been shielding, they will no longer have to shield from the 31st of march. . have to shield from the 31st of march. , ,., ., ~', have to shield from the 31st of march. , ,., ., ., march. greg dawson, thanks for “oininu march. greg dawson, thanks for joining us- _ we are going to stay with the vaccine subject for the moment. the medicines regulator, the mhra, has said there had been five cases of a rare type of blood clot in the brain among 11 million of the shot far outweigh anypossible risks. our health correspondent, nick triggle is with me. five cases out of a lot of doses. explain more. five cases out of a lot of doses. exoiain more-— five cases out of a lot of doses. exlain more. ..,, , ., ., ., explain more. five cases out of more than 10 million _ explain more. five cases out of more than 10 million vaccinations - explain more. five cases out of more than 10 million vaccinations given, i when you 77 7 when you vaccinate so many and when you vaccinate so many people, millions of people, you will always get cases when people die or have an illness after the vaccination, that is natural and will be by coincidence, purely coincidence, and what regulators do, they keep a close eye on the numbers of these adverse events after vaccination to see if they are higher than normal. in face—macro questions were raised about blood clots and the mhra has looked at this and found that for blood clots generally there are no higher rates of blood clots following vaccination then you would expect to happen —— in europe questions were raised. but the focus has been on the rare blood clot which affects the brain and these five cases, people, all men, aged 19—59, and one of the individuals did die. but because this is so rare, the regulator cannot say whether this is higher than you would normally so than you would normally expect, so they are now carrying out more investigations into these individual cases, looking at the of the cases, looking at the history of the patients in what may happen. covid itself, if an infection increases the risk of this blood clot, it is possible these people may have had covid just before vaccination, but they are very clear that there is no evidence to suggest the vaccine has blood clots. the caused these blood clots. the benefits of vaccination far outweigh any of the risks and they say the british public can have confidence in the vaccine. in british public can have confidence in the vaccine.— british public can have confidence in the vaccine. in terms of what is happening — in the vaccine. in terms of what is happening in _ in the vaccine. in terms of what is happening in a — in the vaccine. in terms of what is happening in a lot _ in the vaccine. in terms of what is happening in a lot of— in the vaccine. in terms of what is happening in a lot of eu _ in the vaccine. in terms of what is | happening in a lot of eu countries, we are waiting to see. may be in the hour we will find out what the next hour we will find out what the regulatory agency there is going to advise eu countries. taste regulatory agency there is going to advise eu countries. we understand that they will _ advise eu countries. we understand that they will be _ advise eu countries. we understand that they will be announcing - advise eu countries. we understand that they will be announcing their i that they will be announcing their findings at four o'clock. we know that because they have been looking that because they haveeoeentooking cases that because theyhave—oeenetooking cases more, that because theyhave—beenetooking cases more, we have had more into cases more, we have had more reports of this rare type of blood clot. we will get an update on the numbers they have seen but it will be very hard. i think we will see something similar to the uk regulator, it is very hard to say if these are above the normal threshold and further investigations will need to happen. the european regulator always insisted member states should continue giving the vaccine and it has been the individual decisions of countries like germany and france, italy and spain, to stop the roll—out of the astrazeneca vaccine, so it will be interesting firstly what the european regulator says and then how the individual countries respond to that.— respond to that. nick, thanks for “oininu respond to that. nick, thanks for joining us- _ respond to that. nick, thanks for joining us- you — respond to that. nick, thanks for joining us. you will _ respond to that. nick, thanks for joining us. you will be _ respond to that. nick, thanks for joining us. you will be back- respond to that. nick, thanks for joining us. you will be back to i respond to that. nick, thanks for. joining us. you will be back to talk more once we hear about the eu situation. back to the coronavirus vaccine supply here in the uk — the labour leader, sir keir starmer, was asked about the issue during a visit to a vaccination centre in edinburgh earlier. he said it is a "cause for concern". the vaccine roll—out has been going really, really well and that is a good thing, so i'm concerned about the delays. we need to get to the bottom of it and we need transparency from the government about what the problem is, and i say that in a constructive spirit because everybody needs to be vaccinated as soon as possible but this is obviously a cause of concern, so let's get to the bottom of it and sought it out.— of it and sought it out. some countries _ of it and sought it out. some countries are _ of it and sought it out. some countries are pausing - of it and sought it out. some countries are pausing the i countries are pausing the astrazeneca _ countries are pausing the astrazeneca rolled - countries are pausing the astrazeneca rolled out, i countries are pausing the . astrazeneca rolled out, are countries are pausing the - astrazeneca rolled out, are you worried — astrazeneca rolled out, are you worried more _ astrazeneca rolled out, are you worried more people _ astrazeneca rolled out, are you worried more people will- astrazeneca rolled out, are youj worried more people will refuse astrazeneca rolled out, are you i worried more people will refuse the vaccination? — worried more people will refuse the vaccination? the _ worried more people will refuse the vaccination?— worried more people will refuse the vaccination? ~ , . .. ., .. vaccination? the astrazeneca vaccine is safe and the _ vaccination? the astrazeneca vaccine is safe and the experts _ vaccination? the astrazeneca vaccine is safe and the experts are _ vaccination? the astrazeneca vaccine is safe and the experts are telling i is safe and the experts are telling us it is safe and i would urge everybody who is invited to come forward to have the vaccine. i had astrazeneca last sunday so i'm not just saying this. i've had the vaccine and it is safe and please, if you are invited to come forward, come forward and have the vaccine. do you think the government have been _ do you think the government have been straight _ do you think the government have been straight with _ do you think the government have been straight with the _ do you think the government have been straight with the country- do you think the government have | been straight with the country over the vaccine — been straight with the country over the vaccine delays? _ been straight with the country over the vaccine delays? we _ been straight with the country over the vaccine delays?— been straight with the country over the vaccine delays? we need to hear what they have _ the vaccine delays? we need to hear what they have got _ the vaccine delays? we need to hear what they have got to _ the vaccine delays? we need to hear what they have got to say. _ the vaccine delays? we need to hear what they have got to say. it - the vaccine delays? we need to hear what they have got to say. it is i the vaccine delays? we need to hear what they have got to say. it is a i what they have got to say. it is a cause for concern and we do need to get to the bottom of it and we need transparency but that is said in a constructive tone because we want this to work and no one wants it to fail but this is obviously a cause for concern.— fail but this is obviously a cause for concern. ., ,., ., for concern. the labour leader keir starmer. this afternoon the prime minister will lead today's downing street briefing, he'll be joined by england's chief medical officer chris whitty and drjune raine from the medicines regulatory agency, the mhra. we'll have full coverage from 4.30 on bbc one and the bbc news channel. those on bbc one and the bbc news channel. briefings l five those briefings usually start about five o'clock. the headlines on bbc news... the health secretary says covid vaccination targets will still be met for the nine priority groups, despite a drop in vaccine supply in april. the european medicines agency prepares to deliver its decision about the safety of the astrazeneca jab, after many eu countries paused its rollout. the care regulator says hundreds of patients had "do not resuscitate" notices placed on them at the start of the pandemic — without their knowledge. the care regulator for england has said hundreds of people had their human rights breached when "do not resuscitate" decisions were placed on them during the early part of the pandemic — without them or their families knowing about it. a report by the care quality commission says there's some evidence that blanket dnr decisions — which restrict potentially life—saving treatment — were used on elderly and disabled people. nikki fox reports. hi, everyone, i'm jordan. jordan is supported by dimensions. this is my support worker, emma. hi. we're currently making an omelette. his social care provider is one of many who have fought to remove inappropriate "do not resuscitate" orders during the pandemic. i want me and my friends to grow old and have a happy and fulfilling life, and to have these decisions made for us, against us, in this way i think is very inhumane. it did create a real climate of fear, i think, amongst people with learning disabilities and their families about what the outcomes might be for people. for the "do not resuscitate" orders that you'd heard about, the inappropriate ones, rachel, what were some of the reasons given? we had somebody we support and the reason given for their order was that they had dyspraxia, asthma and a learning disability, which is clearly entirely inappropriate reasons to apply a "do not resuscitate" order. and there are many examples of this. in fact, the care quality commission was told of more than 500 cases where a "do not resuscitate" order was applied without the consent of the person or their family. it said it raised serious concerns that many disabled people were seeing their human rights breached by not being given the right to choose their own end—of—life care. we know at the beginning of the pandemic there i was a lot of confusion. i think some of that confusion - and some of the miscommunication did lead to this increase in dnr cpr decisions that we saw. - it's completely unacceptable. it'sjust terrifying. your life is everything you own, so, scary. sarah, who wants us to protect her identity, has a rare neuromuscular condition. she's in her early 20s and is a successful writer. at the beginning of the pandemic she was asked on three occasions to sign a "do not resuscitate" order. there was no back—and—forth, it was very much, "i think this should happen to you," it was just, "i think this is best." "they wouldn't treat you anyway, let's do it." it was a tick box exercise. i think of a 20—year—old me, i would have been useless at that conversation. i mean, i have had practice, like, i do use a hospice, but this has felt different. this has felt like a fight, which i really don't enjoy. the government says it would take on board the report's recommendations and stressed that blanket "do not resuscitate" orders were always completely unacceptable. nikki fox, bbc news. the health secretary matt hancock has announced more than £6 billion for the nhs in england, partly to deal with waiting lists. earlier, nhs providers, representing hospitals and other trusts in england, said that clearing the backlog of non urgent operations will take years rather than months. recent figures showed that more 300,000 patients in england had waited more than a year for routine surgery. our health editor hugh pym talked to the chief executive of a leading hospital and told me what he had to say. professor marcel levi is chief executive of university college london hospitals trust. he came over to london from the netherlands, where he had an eminent medical career four years ago to take on the role of running the hospital and he goes back to the netherlands at the end of this month to become the dutch government's chief scientific adviser, so his take on the pandemic and the state of the nhs is very, very interesting. a key point he made about these long waits for non—urgent surgery is the nhs already had long waiting lifts before the pandemic and covid was a magnifying glass for that problem because of the cancellations which have created a longer series of waits for people. here's what he had to say on what can be done about that. it's going to take, i'm afraid, a very long time to get where we want to be, at least a year and probably longer. does it need more moneyjust to get through these procedures, doing extra hours and weekends and so on? yes, of course it will take more money and of course we will try to do this as efficient as possible, but you can only treat all those patients if you introduce even more weekend working, evening working, extra shifts, extra operating theatre time. of course that will take a little bit of money. and he was extremely complimentary about the nhs and staff. he paid tribute to those he had worked with and he made a very interesting comment about the nhs�*s role during the pandemic, that it had been involved in some successes, whereas less successful programmes were done by others. everything that has been a success was actually the part that was done by the nhs. everything that was actually not so successful, i'm talking about test and trace, i'm talking about ppe provision, all these things, were actually the things that had to be outsourced to companies that failed in what they promised to deliver, so that's a reminder for the future. professor marcel levi speaking to me. matt hancock has just announced new money for the nhs in england for the first half of the upcoming financial year partly to deal with bringing down these long waiting lists and we will have to await reaction from health leaders as to whether that £6.6 billion is going to be enough. hugh pym, there. an inquest has been opened into the death of sarah everard, whose body was found in woodland a week after she went missing on her way home in south london. the hearing was adjourned until the conclusion of criminal proceedings. our correspondent charlotte wright was at the coroners court in maidstone. it tookjust under half an hour for the inquest to be opened and adjourned today. sarah's mother, father, brother and sister were watching remotely via video link. we heard from the acting detective inspector from the met who is working on the case who went in to some the details that we know surrounding sarah's disappearance. we know she was having dinner with a friend in clapham two weeks ago before she disappeared on her walk home and it was her boyfriend who raised the alarm the next day, concerned about her whereabouts. of course, sarah's body was then discovered the following week last week in an area of woodland just outside ashford in kent. two postmortem examinations have now taken place but today they did not give a medical cause of death. we were told that her body has been given back to herfamily, though, as they continue with the funeral arrangements. a serving met police officer has been charged with her kidnap and murder. a provisional date for the trial has been set for the 25th of october. of course, the inquest won't continue until the criminal proceedings have taken place. adjourning today, the coroner said all that remains to be said to sarah's family for now is just how sorry she is for their loss. the welsh labour party has launched its senedd election campaign with a string of pledges. welsh labour leader and first minister mark drakeford said they want to recreate wales after the pandemic in a way that is fairer, greener and succesful. this is an election of choice about trust and ambition. trust in the government that has the competence and experience to keep leading wales, through the pandemic, and beyond, and ambition to recreate wales after the pandemic is over in a way that is fairer, greener and successful. a way that is fairer, greener and successful-— a way that is fairer, greener and successful. ,, , ., ,, ., with lockdown beginning to ease, a lot of us are looking forward to visiting our beaches, national parks and beauty spots in the coming months. as we saw last year, however — more visitors means more litter, damage and anti—social behaviour. landowners want to tackle those issues with a new "countryside code" — but time is running out, as our environment and rural affairs correspondent claire marshall reports. this was the end of last year's lockdown — people wanted to party — but from the yorkshire dales to bournemouth beach, and across britain, it was often left to armies of volunteers to pick up the pieces. many were drawn to dartmoor national park. on one occasion, we had up to 70 tents in just this small area of common land. they dug fire pits, there were burn marks where they had barbecues, there was litter left all over this area and they were using this area as a human toilet. i came down one sunday, and it almost brought me to tears. you may not know it, but there is actually a government code on how to behave. the thing i enjoy about the countryside the most is the peace. among the rules — don't have barbecues, keep dogs under control and leave no trace. i think you should treat the countryside as you i would treat your home. but this was the last major publicity campaign — it's 17 years old. this website doesn't exist any more. can i go now? author guy shrubsole discovered the government has only spent around £2,000 a year since 2010 promoting the code. i think the government have really neglected their duty to promote the countryside code and the principles of protecting the countryside. they really, really need to start developing a better culture of greater access to nature, but more responsible access to nature. if we don't have the government promoting the countryside code, i don't think we can have politicians turning around and going, "people shouldn't be accessing these places because they don't know how to behave," because the government aren't doing their part in promoting the right behaviours. we've all been cooped up for months, and this is just the kind of place you might want to come — durdle door on england's south coast — but last year after lockdown there was a real litter problem here. and it's notjust that it looks awful — it's the impact on the wildlife. the tide comes in, and it can be washed out to sea and ingested by fish, and also birds come down and feed on it, and the owner is really worried. years ago, we used to have this keep britain tidy- campaign, which banged i on and on and on about it. we see nothing at the moment — absolutely nothing. _ and the impact and the damage — the impact it's having _ on the countryside and the damage it's causing to our environment i is considerable, so it must be worth doing something. i the government says it does have plans to refresh and publicise the code, but in just a few weeks we will be given a lot more freedom. great for us — but it may not be so good for the natural world. claire marshall, bbc news, dorset. it makes you take a breath, just looking at that coastline. now it's time for a look at the weather with tomasz. hello. not much happening over the next few days. it will be staying the same day today and there will be a bit happening but on the whole pretty cloudy. you can see where the clouds are coming in, drifting in from the norwegian sea. riding around this area of high pressure which is parked to the west, southwest of ireland and this is where the high pressure is more or less going to stay over the next few days. you can see the air currents, the wind blowing around the higher, hence the cloud is coming in from the north, but it tends to break up in a few areas. but in other areas, it is thick enough to produce rain. we've had rain in the last day or so. there could be more damp weather anywhere from eastern parts of england, through the east midlands and into the southeast as well, but frost—free for most of us, perhaps a touch of frost where the sky is clear in the coming days. notice tomorrow, there is a very definitive edge between drier, sunnier weather coming in out of the continent and this thicker cloud across the rest of the country. the thinking is from hull to london and southampton there will be sunshine developing on friday afternoon, somewhat drier air heading our way, evaporating those clouds. the high pressure's still with us on saturday, which is the first day of astronomical spring, the vernal equinox, so we well and truly are into spring, but the weather isn't changing much. the wind still blowing out of the north across scotland, perhaps a spot of rain for stornoway. for the rest of the country, it's a case of variable amounts of cloud and this high pressure is still with us through the weekend into next week. the jet stream is way to the north of us, sending the unsettled weather in the direction of iceland and also around the mediterranean, but we're closer to that high. so little change and take a look at this outlook for the next few days. the weather icons indicating clouds or variable amounts of cloud — very difficult to actually indicate on a symbol — with temperatures hovering between 11—13c. the weather will change, but not until later next week. that's it from me. bye— bye. hello, this is bbc news. the headlines: the health secretary says covid vaccination targets will still be met for the nine priority groups, despite a drop in vaccine supply in april. the european medicines agency prepares to deliver its decision about the safety of the astrazeneca jab, after many eu countries paused its rollout. the care regulator says hundreds of patients had "do not resuscitate" notices placed on them at the start of the pandemic without their knowledge. the bbc announces major plans to move large parts of its programme—making out of london, over the next six years. a remarkable collection of handwritten letters from diana princess of wales to a friend are being sold at auction to raise money for arts charities. sport next and let's get a full round up from the bbc sport centre. good afternoon. we'll start at cheltenham where there was more success on day three for rachael blackmore in the ryanair chase. riding the willie mullins trained favourite alla—ho, blackmore lead the race from start to finish, coming home 12 lengths ahead of the rest of the field. fakir do— durrie finished a long way back in second with tornado flyer in third. it's blackmore's fourth winner this week. meanwhile, flooring porter stayed the longest in the stayer�*s hurdle coming home well ahead of the field. sire du berlais was second, whilst the 2019 winner paisley park finished in third. it was jockey danny mullins first win at the festival after five second—place finishes. next to ahmedabad in gujarat where england have been set a target of x to win can win the fourth t20 international against india today. if they chase that down they'll win the series with one match to go. india were put into bat. suryakumar yadav one of the stories of the day, hitting 57 in his first international knock. rohit and rahul less impressive though, whilst virat kohli was bowled by adil rashid for 1. archer took four wickets so england will chase 186 and they will be happy to have prevented india from getting to 200. if england will —— when they will wrap up the series. aston villa's ollie watkins and west brom's sam johnstone have been given their first senior england call—ups, as gareth southgate names his squad for the 2022 world cup qualifiers. jesse lingard, john stones and luke shaw return but here's no place for liverpool defender trent alexander—arnold. watkins, the villa striker, gets his first senior england call up after impressing since joining from brentford in the summer. west brom goalkeeperjohnstone gets his first call up following an injury to england number onejordan pickford. southgate's named a 26—man squad for the qualification triple header against san marino, albania and poland this month. paddy mcnair�*s been included in the northern ireland squad for next week's world cup qualifiers, despite concerns over his fitness. he was forced off with a knee problem in middlesbrough's win over preston in the championship on tuesday night but he still makes the squad. they're away to italy on the 25th, and at home to bulgaria six days later. now to the six nations, and lock adam beard is back in the side for wales's bid to complete a six nations grand slam on saturday when they face france in paris. he was rested for last weekend's win over italy, after starting in their three previous victories. he'll partner captain alun wynjones in the second row. that's coach wayne pivac�*s only change to the line—up. just one change for england too for their match against ireland in dublin. elliot daly will start at outside—centre for the first time in almost five years, replacing the injured henry slade. daly returns after he was relegated to the bench for the win over france last weekend, with max malins starting at number 15. he's had to dig deep into himself and find — he's had to dig deep into himself and find the best of himself. it's been _ and find the best of himself. it's been a _ and find the best of himself. it's been a tough six nations for elliott _ been a tough six nations for elliott i_ been a tough six nations for elliott. ithink been a tough six nations for elliott. i think he is coming back into his — elliott. i think he is coming back into his best form and he's was a great _ into his best form and he's was a great opportunity in his preferred position — wimbledon is likely to go ahead this summer with reduced crowds, organisers have announced today. it's due to start on the 28th ofjune, a week after covid restrictions are set to end in england. there won't be any scenes like this, because there'll be no ticket resales within the grounds. and the traditional ballot won't take place. instead, all tickets will be sold on—line, although there's no word on how many will be available. there were over half a million fans at the all—england club in 2019, the last time the championships were held. in addition, players and their team, and officials, will have to stay in approved hotels, rather than private houses. that's all the sport for now. i'll have more for you in the next hour. the bbc has announced it's to move large parts of its programme making outside london, over the next six years. the director general tim davie says for the first time a majority of network television production will be made outside the capital and much of radio production will be relocated across the country. our media and arts correspondent david sillito has more. six music, at least part of it, is heading to salford. just one of a whole series of bbc services, staff and departments being shifted out of london. the bbc is talking about trying to change its tone, make it feel less london centric. but what it means for people in this building in london is that many of them are being told today they are moving. part of radio three will be going to salford, news beat is going to birmingham, news teams that cover science and the environment to cardiff, the new theme for technology to glasgow. there will also be job losses technology to glasgow. there will also bejob losses in london but today's announcement was all about signalling an attempt to shift both jobs and culture to try to make the bbc feel less southern. the bbc has already moved a programme like bbc breakfast salford and some things it has already made a difference. i has already made a difference. i think it's the case that bv —— bbc breakfast and five live strike a different note in the national conversation and so the fact that northerners like what they get from the team at bbc breakfast means that perhaps they might also like what they get from now what will be business news from salford and a lot more news content from the north of england. more news content from the north of encland. , . . more news content from the north of enland. , ., ., , more news content from the north of encland. ,. ., ,., england. drama is also under the s-uotliht. england. drama is also under the spotlight. eastenders _ england. drama is also under the spotlight. eastenders will - england. drama is also under the spotlight. eastenders will be i england. drama is also under the l spotlight. eastenders will be joined by two new long—running drama series set outside london. there is also hoped that moving £700 million of spending will help spread the countries creative industries. the corporation is facing some tough conversations about the future of the licence fee. this is an attempt to show it both reaches and reflects the whole of the country. the government has said it will cut grants aimed at encouraging people to buy electric vehicles. the department for transport will reduce the grant from three—thousand—pounds to —two—thousand—five—hundred—pounds. it's a move that's been critisised by the motor industry and the society of motor manufacturers and traders have said it's the �*wrong move at the wrong time'. mike dawes is their chief executive and joins me now. it's not a huge drop in the grant, £500 difference, what do you make of it? it £500 difference, what do you make of it? , ., £500 difference, what do you make of it? ,., ., ., £500 difference, what do you make of it? ., £500 difference, what do you make of it? it is also ad'acent to it as a reduction — it? it is also ad'acent to it as a reduction in _ it? it is also adjacent to it as a reduction in the _ it? it is also adjacent to it as a reduction in the eligibility. i it? it is also adjacent to it as a reduction in the eligibility. we| it? it is also adjacent to it as a i reduction in the eligibility. we are now down to probably only half the electric vehicles on the market will be eligible this grant. it said the wrong message. the government has been very clear, it wants is to be at the forefront of this shift towards electrified driving and that's about convincing consumers to buy these vehicles. it's a strange decision to pull the rug from under them and reduce the grant and eligibility. them and reduce the grant and eliuibili . ., them and reduce the grant and elitibili . ., _ , eligibility. the government says reducin t eligibility. the government says reducint it eligibility. the government says reducing it in — eligibility. the government says reducing it in the _ eligibility. the government says reducing it in the way _ eligibility. the government says reducing it in the way it - eligibility. the government says reducing it in the way it has i eligibility. the government says reducing it in the way it has will| reducing it in the way it has will allow it to keep a grant in place for longer and that means by definition more people will ultimately benefit from it. so that is the argument. does that carry any weight for you? tlillie is the argument. does that carry any weight for you?— weight for you? one of the issues is fitted a new — weight for you? one of the issues is fitted a new technology _ weight for you? one of the issues is fitted a new technology and - weight for you? one of the issues is fitted a new technology and new. fitted a new technology and new technologies always expensive. they are in short supply because there is demand for them notjust in the uk but across europe and beyond. so we need to make sure the lion's share of those new vehicles come to the uk. so in terms of where these cars are going to be sent, manufacturers will look at where are the incentives across europe and across elsewhere and we are now getting so far behind some of our major competitor countries like germany and france, they will get much more of these vehicles so the demand might be there but will we get the supply as well? this might be there but will we get the sopply as well?— supply as well? this doesn't help. are we still _ supply as well? this doesn't help. are we still not _ supply as well? this doesn't help. are we still not talking _ supply as well? this doesn't help. are we still not talking about i are we still not talking about issues that have been persistent for some time which is even people who could afford to buy a fully electric car, even people in that income bracket will say i am still quite nervous about investing that much money because there are not enough charging points. you money because there are not enough charging points-— charging points. you are right. the bit test charging points. you are right. the biggest barrier— charging points. you are right. the biggest barrier still _ charging points. you are right. the biggest barrier still is _ charging points. you are right. the biggest barrier still is can - charging points. you are right. the biggest barrier still is can i - biggest barrier still is can i charge the vehicle? if you are lucky enough to have off—street parking you can install a home charger but the grant for that is also going to be removed shortly. it's the biggest obstacle because recharging needs to be as easy as refuelling. if we want to make sure the market moves as quickly as possible we share that ambition with the government and customers need to be content and things need to be convenient. at the moment it's very convenient to refuel your car. you know where the service station is and away you go. 400 miles. you need a different mindset with electric vehicle and above all you need the reassurance that i can charge where i want and when i want and that is another area of major investment that we need if we are to get a verse zero ambition future. �* ., , we are to get a verse zero ambition future. �* . , ., ~ future. but we have been talking about that for _ future. but we have been talking about that for years. _ future. but we have been talking about that for years. you - future. but we have been talking about that for years. you must l future. but we have been talking i about that for years. you must make that point to policymakers. what do they say? that point to policymakers. what do the sa ? , . , ., they say? they are investing on the strate t ic they say? they are investing on the strategic road _ they say? they are investing on the strategic road network _ they say? they are investing on the strategic road network in _ strategic road network in particular. a lot of workers going into that. but it's very about domestic charging we see where the biggest gap is. for all those people who do not have driveways, will pack on the street or in front of their homes. that is where there is a massive gap. the industry is now putting ever more models on the market and they are being taken up. it's no longer the chicken and egg situation. the vehicle height is there and the demand is there but you also need to coincide that with massive investment in infrastructure.- massive investment in infrastructure. ., ,, , massive investment in infrastructure. ., , . infrastructure. thank you very much for now. every day this week we are sharing stories sourced and produced by people between the ages of 11 and 18 as part of the bbc young reporter competition. wilamena is from cornwall and was one of more than two and a half thousand young people who entered this year's competition. her desire to promote understanding about tourette syndrome made her one of the regional winning entries. this is her story. music plays. five years ago, i woke up one day and i couldn't walk or even get out of bed due to disabling and violent full body ticks. eventually, i got diagnosed with tourette syndrome at the age of nine. what age did you first get diagnosed with tourette syndrome? i was five years old when i first got diagnosed with tourette's. i started my first symptoms when i was two. most people with tourette's have what's called a co—morbidity. that could be ocd, adhd, anxiety or depression. the co—morbidity that i have is anxiety and ocd. turns out i'm not the only one. adhd. ocd as well. ocd and adhd. what's really extraordinary is that you don't seem to tick very badly when you're having your cello lessons. bananas in pyjamas. i have a government funded scholarship to attend a specialist music school where i board away from home and learn cello and percussion to an advanced level despite my disability. the moment my fingers touch the piano, the keyboard, i it completely disappears. they go away. my focus is for playing the drums, it almost overtakes the tourette's. even though tourette's can be hard, i try not to let it stop me from reaching my goals. even if myjourney getting there a slightly different from everyone else's. talk to us and treat us like anybody else. we've created such - a stereotype in the media. how can we undo this? people don't understand the unknown and that's what is stressful for people who have tourette's. has your tourette's changed at all as you got older? yeah. there are always kind of, even each day, can have its ups and downs. i started just making small grunting noises from my throat. _ as i got older, they became more physical in my legs _ you name it all, i had all the ticks. with tourette's, - expect the unexpected. how do you think your life would have been different or where would you be now if you hadn't discovered the world of music and how that helped you cope with your ticks? i honestly think i'd be either in one of two places. i'd be dead or injail. tourette's isn'tjust the swearing disease that the media portrays it to be. i want it to stop being the punch line of every comedian's jokes. i want people to learn about what tourette's actually is. this is the real tourette's. that was wilamena. every day this week we're showing stories from some of the winners of the bbc young reporter competition. and tomorrow at 8.30pm there will be a special programme here on the bbc news channel showcasing their work. even if you haven't heard of the social media site reddit, you will have read a news story, shared pictures or watched a video that passed through the site. reddit users submit pictures, comments or news stories which are then voted up or down by other users. and it's proved rather lucrative for some people around the world. now in a rather unusal move, members of a reddit forum have adpoted 3,500 gorillas in six days. we can now speak to the ceo and chief scientific officer at the dian fossey gorilla fund, dr tata stoinski. good afternoon. thanks for having me. explain. it sounds like it's good news for you. is it effectively a big donation? it’s good news for you. is it effectively a big donation?— a big donation? it's a huge donation- _ a big donation? it's a huge donation. it's _ a big donation? it's a huge donation. it's been - a big donation? it's a huge donation. it's been an i a big donation? it's a huge i donation. it's been an amazing thing, the support we have seen from the group. it started on saturday and as i was leaving the us to come to rwanda and it has continued since then. not only is it an amazing financial contribution towards our work to conserve gorillas, but it's also done a greatjob of raising awareness about gorillas and the fact they are endangered. it's not something that a appeal no. == 5; fact they are endangered. it's not something that a appeal no. -- a lot of --eole something that a appeal no. -- a lot of people know _ something that a appeal no. -- a lot of people know. more _ something that a appeal no. -- a lot of people know. more than - something that a appeal no. -- a lot. of people know. more than $350,000 has now been donated. that is a big lump sum i guess. so this is again the power of social media and people connecting online. this is something that comes with the internet i guess. that comes with the internet i utess. . �* . that comes with the internet i utess. . h . , that comes with the internet i utess. , h ., i, that comes with the internet i utess. , h . i, ., ., guess. yes. it's really been amazing to see how — guess. yes. it's really been amazing to see how it's _ guess. yes. it's really been amazing to see how it's gone _ guess. yes. it's really been amazing to see how it's gone viral. _ guess. yes. it's really been amazing to see how it's gone viral. it - guess. yes. it's really been amazing to see how it's gone viral. it is i guess. yes. it's really been amazing to see how it's gone viral. it is a i to see how it's gone viral. it is a lot of individual donations so it is individuals making a difference but the impact collectively is enormous. we've never seen anything like it in the history of our organisation. and the history of our organisation. and so what will — the history of our organisation. and so what will that money go towards? how does it actually allow you and your team to protect these animals? as a nonprofit, all of our money comes from donations. so it's incredible to have this outpouring of support and obviously we will be looking at the areas of critical need and where we can make the biggest impact. we operate in two countries, rwanda protecting mountain gorillas and there are just over 1000 mountain gorillas left on the planet, and we also work in eastern congo. so our work focuses on protection of gorilla families. we do a lot of science to develop conservation strategies. we also do a lot of work to help local communities and build the next generations of conservationists. so these —— this funny —— this money will be important. taste these -- this funny -- this money will be important.— these -- this funny -- this money will be important. we have reflected about the impact _ will be important. we have reflected about the impact of _ will be important. we have reflected about the impact of coronavirus i will be important. we have reflected about the impact of coronavirus on l about the impact of coronavirus on charities and donations. have you been impacted?— been impacted? yes. one of the bit test been impacted? yes. one of the biggest impact _ been impacted? yes. one of the biggest impact for _ been impacted? yes. one of the biggest impact for us _ been impacted? yes. one of the biggest impact for us has - been impacted? yes. one of the biggest impact for us has been l been impacted? yes. one of the l biggest impact for us has been an increase in costs because gorillas just like us are susceptible to coronavirus. so we have had to change our practices in the field to ensure we have a layer of protection and that has increased costs for us on the ground. these funds will help in supporting that. llrrul’eiiii on the ground. these funds will help in supporting that.— in supporting that. well i am glad it's totin in supporting that. well i am glad it's going to _ in supporting that. well i am glad it's going to good _ in supporting that. well i am glad it's going to good use. _ in supporting that. well i am glad it's going to good use. fantastic l it's going to good use. fantastic that you had that donation. all the best to you and good luck in your work. thank you. bt has said it will "build like fury" to roll out full—fibre internet connections after new rules announced by the uk's telecoms regulator. 0fcom has decided not to impose price caps on full—fibre connections provided by the firm's 0penreach subsidiary. this gives the company the certainty it had been looking for ahead of a planned £12bn investment.(read on) we can speak now to our business correspondent vishala sri—pathma. explain more. a full fibre internet connection sounds complicated but what it means is very fast internet. the uk needs to get ready for this roll—out. we don't have the infrastructure in place. what this means is that bt can spend without having to worry about it too much because essentially they can charge whatever they can for this broadband. the idea is that it will incentivise them to get on with the job of implementing the infrastructure and getting it done infrastructure and getting it done in time in the next few years. however, there are some critics of this move because they say it's giving bt that monopoly power. also it means that the price is then passed on the consumer. a collection of letters written by diana princess of wales will be sold at auction today. she wrote them to a close family friend during the 1990s — and the money raised from their sale will go towards arts charities which diana supported. sarah ransome's report does contain flash photography. from farmhouse cupboard to auction house strongroom. for more than 20 years, roger bramble has kept safe these personal letters and cards from diana, princess of wales. he was a close family friend, and this correspondence has remained untouched and private, but is now about to become public. it was a little bit like christmas. it was a real sort of treasure trove. for the auction house, helping this royal collection go public was a privilege. i get a sense of a real continuity, you know, she stayed a warm, loyal, affectionate person, no matter what else was going on, and obviously we know that period was a period of enormous turmoil in her life. her relationship with roger, who they were written to, obviously was a constant. written in the 1990s, some thank her friend for champagne lunches and trips to the ballet. others hint at more turbulent times. as diana's marriage broke down, and media scrutiny intensified, having people to trust became increasingly important. i think it meant a lot to her to stay in touch with people she really cared about, and she opened up to roger about lucia flecha de lima, for example, who was a woman who was close to her mother's age. a small number of friends were absolutely key, probably to her sanity, actually. archive news report: most of the newlyn fleet was in for today's event. whether it were fishing boats, orfactories, diana's charisma went before her. whenever princess diana came to places like this, crowds would gather wherever she went. she came here, to newlyn, to open the new fish market in 1988, and that star quality, that appeal, seems to shine as bright as ever. the auction house says they've had interest in the letters from all over the world. the sale is expected to reach upwards of £30,000, with the proceeds going to organisations close to diana's heart. after reading these, i warmed to her enormously. i think she probably was a lovely person, and i sort of think, oh, she would have been a lovely person to go outwith, to go to one of these wonderful lunches, or something. i think, yeah, it has changed my opinion quite a lot. for the owner, it's not about the money, but the glimpse the letters give into the private world of a princess, who lived so much of her life in the spotlight. sarah ransome, bbc news, penzance. now it's time for a look at the weather with tomasz. hello. there's very little happening on the weather front across the uk in the coming days. it's going to essentially stay more or less the same from day—to—day. there will be a little bit of sunshine developing, but on the whole, pretty cloudy. on the satellite picture, you can see where the clouds are coming from. they are drifting in from the norwegian sea, riding around this area of high pressure which is parked to the west, southwest of ireland and this is where the high pressure is more or less going to stay over the next few days. you can see the air currents, the wind blowing around the higher, hence the cloud is coming in from the north, but it tends to break up in a few areas. but in other areas, it is thick enough to produce rain. we've had rain in the last day or so. there could be more damp weather anywhere from eastern parts of england, through the east midlands and into the southeast as well, but frost—free for most of us, perhaps a touch of frost where the sky is clear in the coming days. notice tomorrow there is a very definitive edge between drier, sunnier weather coming in out of the continent and this thicker cloud across the rest of the country. the thinking is from hull to london and southampton there will be sunshine developing on friday afternoon, somewhat drier air heading our way, evaporating the clouds. the high pressure's still with us on saturday, which is the first day of astronomical spring, the vernal equinox, so we well and truly are into spring, but the weather isn't changing much. the wind still blowing out of the north across scotland, perhaps a spot of rain for stornoway. for the rest of the country, it's a case of variable amounts of cloud and this high pressure is still with us through the weekend into next week. the jet stream is way to the north of us, sending the unsettled weather in the direction of iceland and also around the mediterranean, but we're closer to that high. so little change and take a look at this outlook for the next few days. the weather icons indicating clouds or variable amounts of cloud — very difficult to actually indicate on a symbol — with temperatures hovering between 11—13 celsius. the weather will change, but not until later next week. that's it from me. bye— bye. this is bbc news. i'm clive myrie. the headlines... the health secretary says covid vaccination targets will still be met for priority groups, despite a drop in vaccine supply in april. there will be no weeks in april with no first doses. there will be no cancelled appointments as a result of supply issues. second doses will go ahead as planned. the uk medicines regulator says there is no evidence following five reports of blood clots in people who've had the astrazeneca vaccine — but says there's no evidence they were caused by the jab. will the european medicines regulator give the thumbs up or down, to the astrazeneca jab, after many eu countries paused its rollout, over possible blood clots? the care regulator says hundreds of patients had "do not resuscitate" notices placed on them at the start of the pandemic — without their knowledge. the bbc announces major plans to move large parts of its programme—making out of london, over the next six years. and a remarkable collection of handwritten letters from diana princess of wales to a friend are being sold at auction — to raise money for arts charities. welcome to bbc news. ministers have sought to reassure people about the rollout of the coronavirus vaccine, amid a reduction in supply which means most people in their 40s will now have to wait till may for a jab. the government insists it will still offer all adults their first dose by the end ofjuly — but in the commons earlier today the health secretary confirmed supplies would become tighter in the weeks ahead. we are going to go over to holland where the ema is giving their verdict on the astrazeneca vaccine. we will inform you about the outcome of the discussions, details of the assessment and the next steps. i'm the head of the communication department at ema and i'm delighted to have with me the executive director of ema, emer cooke, and i'm very pleased to introduce to you doctor peter, the head of analytics at ema who can provide additional information about the agencies, scientific procedures if needed. before we start, i want to explain how we plan to run this press briefing. please note that your microphone is disabled by default for the duration of the press briefing. we will first hear short remarks and after that we have half an hour of questions. once the question and answer session begins please raise your hand if you want to ask a question. to raise your hand you will have to click on the icon next to your name in the list of participants. when i give you the floor you will be prompted on your screen to unmute yourself. we would appreciate if you could turn on your camera when you are asking a question. the briefing is being wood being broadcast by youtube and on broadcasters. the footage is free of charge to use. i'm now handing over to emer cooke. charge to use. i'm now handing over to emer cooke-— to emer cooke. thank you. good afternoon. _ to emer cooke. thank you. good afternoon, ladies _ to emer cooke. thank you. good afternoon, ladies and _ to emer cooke. thank you. good j afternoon, ladies and gentlemen to emer cooke. thank you. good i afternoon, ladies and gentlemen and thank— afternoon, ladies and gentlemen and thank you _ afternoon, ladies and gentlemen and thank you forjoining this press briefing — thank you forjoining this press briefing. our expert committee on the safety— briefing. our expert committee on the safety of medicines has now come to a conclusion on the review of cases— to a conclusion on the review of cases of— to a conclusion on the review of cases of blood clots in people vaccinated with astrazeneca's covid-19 _ vaccinated with astrazeneca's covid—19 vaccine. the committee has come _ covid—19 vaccine. the committee has come to— covid—19 vaccine. the committee has come to a _ covid—19 vaccine. the committee has come to a clear scientific conclusion, this is a safe and effective _ conclusion, this is a safe and effective vaccine, its benefits in protecting people from covid—19 with the associated risks of death and hospitalisation outweigh the possible risks. the committee also concluded — possible risks. the committee also concluded that the vaccine is not associated with an increase in the overall— associated with an increase in the overall risk— associated with an increase in the overall risk of thrombotic events or blood _ overall risk of thrombotic events or blood clots — overall risk of thrombotic events or blood clots. during the investigation and review we began to see a _ investigation and review we began to see a small— investigation and review we began to see a small number of cases of rare and unusual— see a small number of cases of rare and unusual but very serious clotting _ and unusual but very serious clotting disorders and this then triggered a more focused review. based _ triggered a more focused review. based on — triggered a more focused review. based on the evidence available, and after days— based on the evidence available, and after days of in—depth analysis of lab results, clinical reports, autopsy— lab results, clinical reports, autopsy reports and further information from the clinical trials. — information from the clinical trials. we _ information from the clinical trials, we still cannot rule out definitively a link between these cases— definitively a link between these cases and the vaccine. what the committee has therefore recommended is to raise _ committee has therefore recommended is to raise awareness of these possible — is to raise awareness of these possible risks, making sure that they are — possible risks, making sure that they are included in the product information. drawing attention to these _ information. drawing attention to these possible rare conditions and providing — these possible rare conditions and providing information to health care professionals and vaccinated people will help _ professionals and vaccinated people will help to spot and mitigate any possible — will help to spot and mitigate any possible side—effects. we're also launching — possible side—effects. we're also launching investigations to understand more about these rare cases— understand more about these rare cases and — understand more about these rare cases and we are conducting targeted observational studies. about 7 million — observational studies. about 7 million people have now been vaccinated in the eu with the astrazeneca vaccine and 11 million have _ astrazeneca vaccine and 11 million have been— astrazeneca vaccine and 11 million have been vaccinated in the uk and there _ have been vaccinated in the uk and there is— have been vaccinated in the uk and there is increasing use of the vaccine — there is increasing use of the vaccine in _ there is increasing use of the vaccine in other countries. it remains _ vaccine in other countries. it remains very important that all side effects— remains very important that all side effects are — remains very important that all side effects are closely monitored and reported — effects are closely monitored and reported it so that we can evaluate them _ reported it so that we can evaluate them and — reported it so that we can evaluate them and see if there is any need to update _ them and see if there is any need to update the — them and see if there is any need to update the information and warnings about— update the information and warnings about possible risks. doctor strauss will explain the evaluation in more detail— will explain the evaluation in more detail but— will explain the evaluation in more detail but i— will explain the evaluation in more detail but i want to reiterate that our scientific position is that this vaccine — our scientific position is that this vaccine is — our scientific position is that this vaccine is a _ our scientific position is that this vaccine is a safe and effective option— vaccine is a safe and effective option to _ vaccine is a safe and effective option to protect citizens against covid-i9~ — option to protect citizens against covid—19. it demonstrated that at least _ covid—19. it demonstrated that at least 60%— covid—19. it demonstrated that at least 60% efficacy in clinical trials — least 60% efficacy in clinical trials in _ least 60% efficacy in clinical trials in preventing coronavirus disease — trials in preventing coronavirus disease and in fact the real world evidence — disease and in fact the real world evidence suggests that the effectiveness could be even higher than that — effectiveness could be even higher than that. we are aware that some member— than that. we are aware that some member states have forced vaccinations waiting for the outcome of the _ vaccinations waiting for the outcome of the review from ema but given that thousands of people in the eu die every— that thousands of people in the eu die every day and in fact over 2500 were _ die every day and in fact over 2500 were reported one day last week, it is really— were reported one day last week, it is really crucial for ema to review rapidly— is really crucial for ema to review rapidly and — is really crucial for ema to review rapidly and thoroughly all the available evidence, so we made these review— available evidence, so we made these review our— available evidence, so we made these review our highest priority. our experts — review our highest priority. our experts have worked intensively to analyse _ experts have worked intensively to analyse in — experts have worked intensively to analyse in great detail all the data available — analyse in great detail all the data available. we have mobilised european experts in the field of thrombosis and blood disorders to investigate and we have worked closely — investigate and we have worked closely with other health authorities across the world, including _ authorities across the world, including with the uk's mhra. you scientific— including with the uk's mhra. you scientific conclusions provide member— scientific conclusions provide member states with the information they need _ member states with the information they need to take an informed decision— they need to take an informed decision decision regarding the use of the _ decision decision regarding the use of the astrazeneca vaccine in their vaccination — of the astrazeneca vaccine in their vaccination campaigns. before i hand over to _ vaccination campaigns. before i hand over to doctor strauss i would like to highlight the situation like the one we _ to highlight the situation like the one we have just seen here is not unexpected. when you vaccinate millions — unexpected. when you vaccinate millions of people, it is inevitable that rare — millions of people, it is inevitable that rare and serious instances of illness _ that rare and serious instances of illness will — that rare and serious instances of illness will occur in the time immediately following vaccination. our immediately following vaccination. 0ur role _ immediately following vaccination. 0ur role in — immediately following vaccination. our role in the eu regulatory system is to rapidly— our role in the eu regulatory system is to rapidly detect in these instances and investigate whether there _ instances and investigate whether there may be a link to the vaccine or whether— there may be a link to the vaccine or whether they are the result of things— or whether they are the result of things which occur by chance close in time _ things which occur by chance close in time to— things which occur by chance close in time to the vaccination. we are committed — in time to the vaccination. we are committed to make sure that any new suspected _ committed to make sure that any new suspected adverse reaction is rapidly— suspected adverse reaction is rapidly investigated to support decisions based on science which can then support confidence in vaccines which _ then support confidence in vaccines which is _ then support confidence in vaccines which is so — then support confidence in vaccines which is so important in dealing with this — which is so important in dealing with this devastating pandemic we are facing — with this devastating pandemic we are facing and we remain fully mobilised to make sure our public health— mobilised to make sure our public health role. today's conclusion helps _ health role. today's conclusion helps us — health role. today's conclusion helps us to continue the fight against — helps us to continue the fight against the pandemic by raising awareness and providing up—to—date information— awareness and providing up—to—date information as we can... as we have analysed _ information as we can... as we have analysed it _ information as we can... as we have analysed it and as it becomes available, so that citizens across europe _ available, so that citizens across europe are — available, so that citizens across europe are informed about what they need to— europe are informed about what they need to do _ europe are informed about what they need to do. thank you very much. thank— need to do. thank you very much. thank you — need to do. thank you very much. thank you very much, now i hand over to doctor strauss.— to doctor strauss. thank you very much. to doctor strauss. thank you very much- good _ to doctor strauss. thank you very much. good afternoon. _ to doctor strauss. thank you very much. good afternoon. the i to doctor strauss. thank you very much. good afternoon. the risk l much. good afternoon. the risk assessment— much. good afternoon. the risk assessment committee - much. good afternoon. the risk assessment committee that i i much. good afternoon. the risk. assessment committee that i chair has looked — assessment committee that i chair has looked in — assessment committee that i chair has looked in great _ assessment committee that i chair has looked in great detail- assessment committee that i chair has looked in great detail at - assessment committee that i chair has looked in great detail at the i has looked in great detail at the cases— has looked in great detail at the cases of— has looked in great detail at the cases of not— has looked in great detail at the cases of not clots _ has looked in great detail at the cases of not clots reported i has looked in great detail at thej cases of not clots reported after vaccination _ cases of not clots reported after vaccination with _ cases of not clots reported after vaccination with covid—19 - cases of not clots reported afterl vaccination with covid—19 vaccine astrazeneca _ vaccination with covid—19 vaccine astrazeneca. as _ vaccination with covid—19 vaccine astrazeneca. as soon _ vaccination with covid—19 vaccine astrazeneca. as soon as - vaccination with covid—19 vaccine astrazeneca. as soon as these . astrazeneca. as soon as these concerns — astrazeneca. as soon as these concerns arose _ astrazeneca. as soon as these concerns arose last _ astrazeneca. as soon as these concerns arose last week, i astrazeneca. as soon as these concerns arose last week, the | concerns arose last week, the committee _ concerns arose last week, the committee started _ concerns arose last week, the committee started a - concerns arose last week, the i committee started a comprehensive review _ committee started a comprehensive review of— committee started a comprehensive review of all — committee started a comprehensive review of all the _ committee started a comprehensive review of all the available _ review of all the available evidence, _ review of all the available evidence, and _ review of all the available evidence, and working i review of all the available i evidence, and working around review of all the available - evidence, and working around the clock— evidence, and working around the clock making _ evidence, and working around the clock making use _ evidence, and working around the clock making use of— evidence, and working around the clock making use of all— evidence, and working around the clock making use of all the - clock making use of all the resources _ clock making use of all the resources at _ clock making use of all the resources at our _ clock making use of all the resources at our disposal. i clock making use of all the| resources at our disposal. i clock making use of all the i resources at our disposal. i want clock making use of all the - resources at our disposal. i want to thank— resources at our disposal. i want to thank colleagues _ resources at our disposal. i want to thank colleagues from _ resources at our disposal. i want to thank colleagues from the - resources at our disposal. i want to thank colleagues from the belgianl thank colleagues from the belgian team that — thank colleagues from the belgian team that have _ thank colleagues from the belgian team that have led _ thank colleagues from the belgian team that have led the _ thank colleagues from the belgianl team that have led the assessment and work— team that have led the assessment and work side — team that have led the assessment and work side by— team that have led the assessment and work side by side _ team that have led the assessment and work side by side with - and work side by side with colleagues _ and work side by side with colleagues from _ and work side by side with colleagues from national i and work side by side with - colleagues from national competent authorities— colleagues from national competent authorities and _ colleagues from national competent authorities and the _ colleagues from national competent authorities and the european - authorities and the european medicines _ authorities and the european medicines agency— authorities and the european medicines agency as - authorities and the european medicines agency as well i authorities and the european medicines agency as well as| medicines agency as well as scientific— medicines agency as well as scientific experts— medicines agency as well as scientific experts in - medicines agency as well as scientific experts in blood i scientific experts in blood disorders— scientific experts in blood disorders who _ scientific experts in blood disorders who will - scientific experts in blood disorders who will be i scientific experts in blood l disorders who will be asked scientific experts in blood i disorders who will be asked to provide — disorders who will be asked to provide advice _ disorders who will be asked to provide advice in _ disorders who will be asked to provide advice in the - disorders who will be asked to i provide advice in the assessments. we have _ provide advice in the assessments. we have come _ provide advice in the assessments. we have come to _ provide advice in the assessments. we have come to the _ provide advice in the assessments. we have come to the following i we have come to the following conclusions, _ we have come to the following conclusions, this— we have come to the following conclusions, this vaccine i we have come to the following conclusions, this vaccine is i we have come to the followingl conclusions, this vaccine is safe and effective _ conclusions, this vaccine is safe and effective in— conclusions, this vaccine is safe and effective in preventing - conclusions, this vaccine is safe - and effective in preventing covid—19 and effective in preventing covid—19 and its _ and effective in preventing covid—19 and its benefits— and effective in preventing covid—19 and its benefits continue _ and effective in preventing covid—19 and its benefits continue to - and effective in preventing covid—19 and its benefits continue to be - and effective in preventing covid—19 and its benefits continue to be far. and its benefits continue to be far greater— and its benefits continue to be far greater then— and its benefits continue to be far greater than its _ and its benefits continue to be far greater than its risks. _ and its benefits continue to be far greater than its risks. we - and its benefits continue to be far greater than its risks. we have i greater than its risks. we have found — greater than its risks. we have found no— greater than its risks. we have found no evidence _ greater than its risks. we have found no evidence of _ greater than its risks. we have found no evidence of a - greater than its risks. we have found no evidence of a qualityl greater than its risks. we have i found no evidence of a quality or greater than its risks. we have - found no evidence of a quality or a batch _ found no evidence of a quality or a batch issue. — found no evidence of a quality or a batch issue, and _ found no evidence of a quality or a batch issue, and the _ found no evidence of a quality or a batch issue, and the committee i found no evidence of a quality oral batch issue, and the committee has assessed _ batch issue, and the committee has assessed and — batch issue, and the committee has assessed and discussed _ batch issue, and the committee has assessed and discussed preclinical. assessed and discussed preclinical and clinical— assessed and discussed preclinical and clinical trial— assessed and discussed preclinical and clinical trial data, _ assessed and discussed preclinical and clinical trial data, published i and clinical trial data, published literature — and clinical trial data, published literature and _ and clinical trial data, published literature and adverse _ and clinical trial data, published literature and adverse events i literature and adverse events related — literature and adverse events related to _ literature and adverse events related to the _ literature and adverse events related to the blood - literature and adverse events related to the blood clots - literature and adverse events| related to the blood clots that literature and adverse events - related to the blood clots that have occurred _ related to the blood clots that have occurred during _ related to the blood clots that have occurred during the _ related to the blood clots that have occurred during the vaccination - occurred during the vaccination campaign _ occurred during the vaccination campaign. reported _ occurred during the vaccination campaign. reported by- occurred during the vaccination campaign. reported by those i occurred during the vaccination i campaign. reported by those who occurred during the vaccination - campaign. reported by those who have been vaccinated _ campaign. reported by those who have been vaccinated and _ campaign. reported by those who have been vaccinated and health _ campaign. reported by those who have been vaccinated and health care - been vaccinated and health care professionals _ been vaccinated and health care professionals. critical— been vaccinated and health care professionals. criticalto- been vaccinated and health care professionals. critical to the - professionals. critical to the review— professionals. critical to the review has— professionals. critical to the review has been _ professionals. critical to the review has been the - professionals. critical to the review has been the careful| review has been the careful scientific— review has been the careful scientific assessments - review has been the careful scientific assessments and i review has been the careful- scientific assessments and clinical scrutiny— scientific assessments and clinical scrutiny of— scientific assessments and clinical scrutiny of the _ scientific assessments and clinical scrutiny of the individual- scientific assessments and clinical scrutiny of the individual cases - scrutiny of the individual cases from _ scrutiny of the individual cases from the — scrutiny of the individual cases from the different _ scrutiny of the individual cases from the different member- scrutiny of the individual cases - from the different member states. we noted _ from the different member states. we noted that— from the different member states. we noted that a _ from the different member states. we noted that a number— from the different member states. we noted that a number of— from the different member states. we noted that a number of these - from the different member states. we noted that a number of these events l noted that a number of these events reported _ noted that a number of these events reported after— noted that a number of these events reported after vaccination _ noted that a number of these events reported after vaccination is - noted that a number of these events reported after vaccination is lower i reported after vaccination is lower than the _ reported after vaccination is lower than the expected _ reported after vaccination is lower than the expected in _ reported after vaccination is lower than the expected in the - reported after vaccination is lower than the expected in the general. than the expected in the general population. _ than the expected in the general population. and _ than the expected in the general population, and we _ than the expected in the general population, and we have - than the expected in the general. population, and we have concluded that there — population, and we have concluded that there is — population, and we have concluded that there is no _ population, and we have concluded that there is no increase _ population, and we have concluded that there is no increase in- population, and we have concluded that there is no increase in the - that there is no increase in the overall— that there is no increase in the overall risk— that there is no increase in the overall risk of— that there is no increase in the overall risk of blood _ that there is no increase in the overall risk of blood clots - that there is no increase in the overall risk of blood clots with| overall risk of blood clots with this vaccine. _ overall risk of blood clots with this vaccine. more _ overall risk of blood clots with this vaccine. more over, - overall risk of blood clots with i this vaccine. more over, because overall risk of blood clots with - this vaccine. more over, because the vaccine _ this vaccine. more over, because the vaccine is _ this vaccine. more over, because the vaccine is effective _ this vaccine. more over, because the vaccine is effective in— this vaccine. more over, because the vaccine is effective in preventing - vaccine is effective in preventing covid-19 — vaccine is effective in preventing covid—19 disease, _ vaccine is effective in preventing covid—19 disease, which - vaccine is effective in preventing covid—19 disease, which in - vaccine is effective in preventing covid—19 disease, which in itself| vaccine is effective in preventing l covid—19 disease, which in itself is a cause _ covid—19 disease, which in itself is a cause of— covid—19 disease, which in itself is a cause of blood _ covid—19 disease, which in itself is a cause of blood clots, _ covid—19 disease, which in itself is a cause of blood clots, it - covid—19 disease, which in itself is a cause of blood clots, it likely- a cause of blood clots, it likely reduces — a cause of blood clots, it likely reduces the _ a cause of blood clots, it likely reduces the risks _ a cause of blood clots, it likely reduces the risks of _ a cause of blood clots, it likely| reduces the risks of thrombotic events— reduces the risks of thrombotic events overall. _ reduces the risks of thrombotic events overall. however, - reduces the risks of thrombotic events overall. however, there reduces the risks of thrombotic- events overall. however, there are also still _ events overall. however, there are also still some _ events overall. however, there are also still some uncertainties. - events overall. however, there are also still some uncertainties. we . also still some uncertainties. we have _ also still some uncertainties. we have seen— also still some uncertainties. we have seen some _ also still some uncertainties. we have seen some very— also still some uncertainties. we have seen some very rare - also still some uncertainties. we have seen some very rare case i have seen some very rare case reports. — have seen some very rare case reports, describing _ have seen some very rare case reports, describing specific- have seen some very rare case - reports, describing specific unusual events— reports, describing specific unusual events of— reports, describing specific unusual events of a — reports, describing specific unusual events of a combination _ reports, describing specific unusual events of a combination of - events of a combination of thrombosis— events of a combination of thrombosis and _ events of a combination of thrombosis and bleeding. i events of a combination of i thrombosis and bleeding. in events of a combination of. thrombosis and bleeding. in a events of a combination of - thrombosis and bleeding. in a few cases. _ thrombosis and bleeding. in a few cases. tinv— thrombosis and bleeding. in a few cases, tiny clots _ thrombosis and bleeding. in a few cases, tiny clots developed - thrombosis and bleeding. in a few cases, tiny clots developed in - cases, tiny clots developed in nruttipte _ cases, tiny clots developed in multiple blood _ cases, tiny clots developed in multiple blood vessels - cases, tiny clots developed in multiple blood vessels in - cases, tiny clots developed in multiple blood vessels in the| cases, tiny clots developed in - multiple blood vessels in the first 7-14 davs — multiple blood vessels in the first 7-14 days after _ multiple blood vessels in the first 7—14 days after vaccination. - multiple blood vessels in the first 7—14 days after vaccination. alsol multiple blood vessels in the first. 7—14 days after vaccination. also in a few— 7—14 days after vaccination. also in a few cases — 7—14 days after vaccination. also in a few cases we _ 7—14 days after vaccination. also in a few cases we saw _ 7—14 days after vaccination. also in a few cases we saw clots _ 7—14 days after vaccination. also in. a few cases we saw clots developing in blood _ a few cases we saw clots developing in blood vessels _ a few cases we saw clots developing in blood vessels draining _ a few cases we saw clots developing in blood vessels draining blood - a few cases we saw clots developingi in blood vessels draining blood from the ttrain— in blood vessels draining blood from the brain and— in blood vessels draining blood from the brain and this _ in blood vessels draining blood from the brain and this condition - in blood vessels draining blood from the brain and this condition is- the brain and this condition is known — the brain and this condition is known as— the brain and this condition is known as a _ the brain and this condition is known as a cerebral - the brain and this condition is known as a cerebral venous l the brain and this condition is- known as a cerebral venous sinus thrombosis _ known as a cerebral venous sinus thrombosis. these _ known as a cerebral venous sinus thrombosis. these conditions - known as a cerebral venous sinus thrombosis. these conditions are linked _ thrombosis. these conditions are linked to— thrombosis. these conditions are linked to tow— thrombosis. these conditions are linked to low levels _ thrombosis. these conditions are linked to low levels of— thrombosis. these conditions are linked to low levels of platelets. i linked to low levels of platelets. and the — linked to low levels of platelets. and the evidence _ linked to low levels of platelets. and the evidence we _ linked to low levels of platelets. and the evidence we have - linked to low levels of platelets. and the evidence we have at - linked to low levels of platelets. and the evidence we have at the nronrent— and the evidence we have at the moment is— and the evidence we have at the moment is not— and the evidence we have at the moment is not sufficient- and the evidence we have at the moment is not sufficient to - and the evidence we have at the - moment is not sufficient to conclude with certainty— moment is not sufficient to conclude with certainty whether— moment is not sufficient to conclude with certainty whether these - moment is not sufficient to conclude| with certainty whether these adverse events _ with certainty whether these adverse events are _ with certainty whether these adverse events are indeed _ with certainty whether these adverse events are indeed caused _ with certainty whether these adverse events are indeed caused by- with certainty whether these adverse events are indeed caused by the - events are indeed caused by the vaccine — events are indeed caused by the vaccine or— events are indeed caused by the vaccine or not _ events are indeed caused by the vaccine or not. so _ events are indeed caused by the vaccine or not. so we _ events are indeed caused by the vaccine or not. so we will - events are indeed caused by the . vaccine or not. so we will continue to gather— vaccine or not. so we will continue to gather more _ vaccine or not. so we will continue to gather more information - vaccine or not. so we will continue to gather more information on - vaccine or not. so we will continue l to gather more information on these conditions _ to gather more information on these conditions including _ to gather more information on these conditions including additional- conditions including additional studies — conditions including additional studies and _ conditions including additional studies and we _ conditions including additional studies and we will _ conditions including additional studies and we will keep - conditions including additionali studies and we will keep them conditions including additional- studies and we will keep them under very close _ studies and we will keep them under very close monitoring. _ studies and we will keep them under very close monitoring. we _ studies and we will keep them under very close monitoring. we also - very close monitoring. we also concluded _ very close monitoring. we also concluded that— very close monitoring. we also concluded that it _ very close monitoring. we also concluded that it is _ very close monitoring. we also concluded that it is very- very close monitoring. we also i concluded that it is very important that these — concluded that it is very important that these events _ concluded that it is very important that these events are _ concluded that it is very important that these events are rare, - concluded that it is very important that these events are rare, and i concluded that it is very important that these events are rare, and asi that these events are rare, and as of tast— that these events are rare, and as of last night — that these events are rare, and as of last night seven _ that these events are rare, and as of last night seven cases - that these events are rare, and as of last night seven cases of- that these events are rare, and as of last night seven cases of this i of last night seven cases of this disseminated _ of last night seven cases of this disseminated intravascular- disseminated intravascular coagulation _ disseminated intravascular coagulation were - disseminated intravascular coagulation were reported | disseminated intravascular. coagulation were reported out disseminated intravascular- coagulation were reported out of almost _ coagulation were reported out of almost 20 — coagulation were reported out of almost 20 million _ coagulation were reported out of almost 20 million vaccinated - coagulation were reported out of - almost 20 million vaccinated people. furthermore. — almost 20 million vaccinated people. furthermore, such _ almost 20 million vaccinated people. furthermore, such cases _ almost 20 million vaccinated people. furthermore, such cases were - almost 20 million vaccinated people. furthermore, such cases were not i furthermore, such cases were not identified — furthermore, such cases were not identified in— furthermore, such cases were not identified in the _ furthermore, such cases were not identified in the large _ furthermore, such cases were not identified in the large clinical- identified in the large clinical trials — identified in the large clinical trials but _ identified in the large clinical trials but that _ identified in the large clinical trials but that highlights - identified in the large clinical trials but that highlights the| trials but that highlights the importance _ trials but that highlights the importance of— trials but that highlights the importance of being - trials but that highlights the importance of being vigilanti trials but that highlights the - importance of being vigilant once the vaccine — importance of being vigilant once the vaccine is _ importance of being vigilant once the vaccine is administered - importance of being vigilant once the vaccine is administered to - importance of being vigilant once . the vaccine is administered to large populations — the vaccine is administered to large populations we _ the vaccine is administered to large populations. we also _ the vaccine is administered to large populations. we also felt _ the vaccine is administered to large populations. we also felt that - the vaccine is administered to large populations. we also felt that it - the vaccine is administered to large populations. we also felt that it is i populations. we also felt that it is of great _ populations. we also felt that it is of great importance _ populations. we also felt that it is of great importance that - populations. we also felt that it is of great importance that health i populations. we also felt that it is l of great importance that health care professionals — of great importance that health care professionals and _ of great importance that health care professionals and people _ of great importance that health care professionals and people coming - of great importance that health care professionals and people coming for a vaccination — professionals and people coming for a vaccination are _ professionals and people coming for a vaccination are aware _ professionals and people coming for a vaccination are aware of— professionals and people coming for a vaccination are aware of these - a vaccination are aware of these possible — a vaccination are aware of these possible adverse _ a vaccination are aware of these possible adverse events - a vaccination are aware of these possible adverse events and - a vaccination are aware of thesel possible adverse events and that they can — possible adverse events and that they can spot _ possible adverse events and that they can spot possible _ possible adverse events and that they can spot possible signs - possible adverse events and that they can spot possible signs of. they can spot possible signs of symptoms— they can spot possible signs of symptoms that _ they can spot possible signs of symptoms that may— they can spot possible signs of symptoms that may occur- they can spot possible signs of| symptoms that may occur after they can spot possible signs of- symptoms that may occur after the vaccination — symptoms that may occur after the vaccination. therefore, _ symptoms that may occur after the vaccination. therefore, we - symptoms that may occur after the vaccination. therefore, we have i vaccination. therefore, we have recommended _ vaccination. therefore, we have recommended to _ vaccination. therefore, we have recommended to add _ vaccination. therefore, we have recommended to add a - vaccination. therefore, we have recommended to add a warning| vaccination. therefore, we have . recommended to add a warning to vaccination. therefore, we have - recommended to add a warning to the leaflet— recommended to add a warning to the leaflet and _ recommended to add a warning to the leaflet and a _ recommended to add a warning to the leaflet and a description _ recommended to add a warning to the leaflet and a description of— recommended to add a warning to the leaflet and a description of these - leaflet and a description of these cases _ leaflet and a description of these cases so — leaflet and a description of these cases so that— leaflet and a description of these cases. so that this _ leaflet and a description of these cases. so that this information . cases. so that this information which — cases. so that this information which should _ cases. so that this information which should be _ cases. so that this information which should be provided - cases. so that this information which should be provided to i cases. so that this information - which should be provided to health care professionals— which should be provided to health care professionals and _ which should be provided to health care professionals and to - which should be provided to health care professionals and to the - care professionals and to the public — care professionals and to the public ema _ care professionals and to the public. ema a _ care professionals and to the public. ema a national- care professionals and to the | public. ema a national health authorities— public. ema a national health authorities will— public. ema a national health authorities will make - public. ema a national health authorities will make sure - public. ema a national health. authorities will make sure that health— authorities will make sure that health care _ authorities will make sure that health care professionals - authorities will make sure that health care professionals and i authorities will make sure that. health care professionals and the general— health care professionals and the general public _ health care professionals and the general public are _ health care professionals and the general public are made - health care professionals and the general public are made aware i health care professionals and the general public are made aware of this information _ general public are made aware of this information and _ general public are made aware of this information and made - general public are made aware of this information and made aware| general public are made aware of. this information and made aware of the signs— this information and made aware of the signs and — this information and made aware of the signs and symptoms _ this information and made aware of the signs and symptoms of- this information and made aware of the signs and symptoms of concerni this information and made aware of. the signs and symptoms of concern so that timely— the signs and symptoms of concern so that timely action _ the signs and symptoms of concern so that timely action can _ the signs and symptoms of concern so that timely action can be _ the signs and symptoms of concern so that timely action can be taken - the signs and symptoms of concern so that timely action can be taken to - that timely action can be taken to mitigate — that timely action can be taken to mitigate these _ that timely action can be taken to mitigate these risks. _ that timely action can be taken to mitigate these risks. with- that timely action can be taken to mitigate these risks. with that i i mitigate these risks. with that i would _ mitigate these risks. with that i would like — mitigate these risks. with that i would like to _ mitigate these risks. with that i would like to hand _ mitigate these risks. with that i would like to hand back. - mitigate these risks. with that i would like to hand back. many. would like to hand back. many thanks. would like to hand back. many thanks we — would like to hand back. many thanks. we are _ would like to hand back. many thanks. we are now _ would like to hand back. many thanks. we are now going - would like to hand back. many thanks. we are now going to l would like to hand back— thanks. we are now going to open the floorfor thanks. we are now going to open the floor for questions. thanks. we are now going to open the floorfor questions. if thanks. we are now going to open the floor for questions. if you wish to ask a question please click on the raised hand icon which appears when you move your mouse over your name in the list of participants. when i give you the floor you will be asked to unmute yourself and you can then start by stating your name and affiliation. let's see who would like to ask a question... so far i don't see anybody. do we have any questions? 0k. gabrielle, can you ask your question? hello, everybody. gabrielle from italian _ hello, everybody. gabrielle from italian tv~ — hello, everybody. gabrielle from italian tv. do you think that the application of the principle of precaution by more than 15 states like germany, france and italy, is going _ like germany, france and italy, is going to _ like germany, france and italy, is going to undermine the trust of the population in the astrazeneca vaccine? _ population in the astrazeneca vaccine? . . . population in the astrazeneca vaccine? . , , .., population in the astrazeneca vaccine? . , , ., vaccine? perhaps i can ask emer cooke to reply — vaccine? perhaps i can ask emer cooke to reply to _ vaccine? perhaps i can ask emer cooke to reply to this _ vaccine? perhaps i can ask emer cooke to reply to this question. | cooke to reply to this question. thank you very much for the question _ thank you very much for the question a— thank you very much for the question. a lot _ thank you very much for the question. a lot of— thank you very much for the question. a lot of member. thank you very much for the - question. a lot of member states are waiting _ question. a lot of member states are waiting for— question. a lot of member states are waiting for this — question. a lot of member states are waiting for this outcome _ question. a lot of member states are waiting for this outcome of _ question. a lot of member states are waiting for this outcome of the - waiting for this outcome of the safety— waiting for this outcome of the safety review _ waiting for this outcome of the safety review and _ waiting for this outcome of the safety review and they - waiting for this outcome of the safety review and they have i safety review and they have indicated _ safety review and they have indicated to _ safety review and they have indicated to us _ safety review and they have indicated to us that - safety review and they have indicated to us that what i safety review and they have . indicated to us that what ema safety review and they have - indicated to us that what ema has done _ indicated to us that what ema has done from — indicated to us that what ema has done from a — indicated to us that what ema has done from a scientific— indicated to us that what ema has done from a scientific perspective| done from a scientific perspective is very— done from a scientific perspective is very important _ done from a scientific perspective is very important for— done from a scientific perspective is very important for them - done from a scientific perspective is very important for them to - done from a scientific perspective. is very important for them to make done from a scientific perspective i is very important for them to make a decision— is very important for them to make a decision on— is very important for them to make a decision on how— is very important for them to make a decision on how to _ is very important for them to make a decision on how to continue - is very important for them to make a decision on how to continue with - is very important for them to make a decision on how to continue with the | decision on how to continue with the vaccination, — decision on how to continue with the vaccination, so— decision on how to continue with the vaccination, so we _ decision on how to continue with the vaccination, so we are _ decision on how to continue with the vaccination, so we are delivering - decision on how to continue with the vaccination, so we are delivering on| vaccination, so we are delivering on that promise — vaccination, so we are delivering on that promise today. _ vaccination, so we are delivering on that promise today. our— that promise today. our responsibility— that promise today. our responsibility is- that promise today. our responsibility is to - that promise today. 0ur| responsibility is to come that promise today. our. responsibility is to come to that promise today. our- responsibility is to come to a conclusion— responsibility is to come to a conclusion as _ responsibility is to come to a conclusion as to _ responsibility is to come to a conclusion as to whether - responsibility is to come to a conclusion as to whether or. responsibility is to come to a . conclusion as to whether or not responsibility is to come to a - conclusion as to whether or not the benefits— conclusion as to whether or not the benefits outweigh _ conclusion as to whether or not the benefits outweigh the _ conclusion as to whether or not the benefits outweigh the risks - conclusion as to whether or not the benefits outweigh the risks of- conclusion as to whether or not the benefits outweigh the risks of the i benefits outweigh the risks of the vaccines — benefits outweigh the risks of the vaccines so — benefits outweigh the risks of the vaccines so that _ benefits outweigh the risks of the vaccines so that countries - benefits outweigh the risks of the vaccines so that countries can - benefits outweigh the risks of the . vaccines so that countries can make an informed — vaccines so that countries can make an informed decision _ vaccines so that countries can make an informed decision and _ vaccines so that countries can make an informed decision and increase l an informed decision and increase trust _ an informed decision and increase trust in _ an informed decision and increase trust in the — an informed decision and increase trust in the vaccine. _ an informed decision and increase trust in the vaccine.— an informed decision and increase trust in the vaccine. many thanks. susie from — trust in the vaccine. many thanks. susie from bloomberg _ trust in the vaccine. many thanks. susie from bloomberg is - trust in the vaccine. many thanks. susie from bloomberg is next - trust in the vaccine. many thanks. susie from bloomberg is next in l susie from bloomberg is next in line. go ahead.— susie from bloomberg is next in line. go ahead. could you clarify, if there is — line. go ahead. could you clarify, if there is any _ line. go ahead. could you clarify, if there is any link _ line. go ahead. could you clarify, if there is any link found - line. go ahead. could you clarify, i if there is any link found between these _ if there is any link found between these cases— if there is any link found between these cases and _ if there is any link found between these cases and the _ if there is any link found between these cases and the vaccine, - if there is any link found between| these cases and the vaccine, what further— these cases and the vaccine, what further steps _ these cases and the vaccine, what further steps you _ these cases and the vaccine, what further steps you may _ these cases and the vaccine, what further steps you may take - these cases and the vaccine, what further steps you may take with l further steps you may take with that? _ further steps you may take with that? and — further steps you may take with that? and could _ further steps you may take with that? and could you _ further steps you may take with that? and could you give - further steps you may take with . that? and could you give specifics around _ that? and could you give specifics around what — that? and could you give specifics around what kind _ that? and could you give specifics around what kind of— that? and could you give specifics around what kind of a _ that? and could you give specifics around what kind of a label- that? and could you give specifics| around what kind of a label update we may— around what kind of a label update we may see? _ around what kind of a label update we may see? is— around what kind of a label update we may see? is it _ around what kind of a label update we may see? is itjust— around what kind of a label update we may see? is itjust related - around what kind of a label update we may see? is itjust related to. we may see? is itjust related to these _ we may see? is itjust related to these conditions _ we may see? is itjust related to these conditions or— we may see? is itjust related to these conditions or general- these conditions or general information— these conditions or general information about - these conditions or general information about the - these conditions or generali information about the blood these conditions or general- information about the blood clot awareness? _ information about the blood clot awareness?— awareness? doctor strauss can resond awareness? doctor strauss can respond to — awareness? doctor strauss can respond to this. _ awareness? doctor strauss can respond to this. thank- awareness? doctor strauss can respond to this. thank you. - awareness? doctor strauss can i respond to this. thank you. we awareness? doctor strauss can - respond to this. thank you. we have concluded that _ respond to this. thank you. we have concluded that there _ respond to this. thank you. we have concluded that there is _ respond to this. thank you. we have concluded that there is a _ respond to this. thank you. we have concluded that there is a proposal. concluded that there is a proposal to update — concluded that there is a proposal to update section 4.4, the boarding section— to update section 4.4, the boarding section of— to update section 4.4, the boarding section of the summary of the product — section of the summary of the product characteristics —— warning section~ _ product characteristics —— warning section~ and — product characteristics —— warning section. and also the patient leaflet~ — section. and also the patient leaflet. because this is a very special— leaflet. because this is a very special situation, though, we are also discussing tools and means to reach _ also discussing tools and means to reach out _ also discussing tools and means to reach out to the more general public and also _ reach out to the more general public and also a _ reach out to the more general public and also a health care professional letter— and also a health care professional letter which is a term to be used for information which is being sent to health _ for information which is being sent to health care professionals all over— to health care professionals all over europe in order to make them aware _ over europe in order to make them aware of— over europe in order to make them aware of this additional information and to— aware of this additional information and to help them mitigate the risks in case _ and to help them mitigate the risks in case patients might suffer from these _ in case patients might suffer from these signs and symptoms and we are also highlighting to all the population that is being vaccinated, to what— population that is being vaccinated, to what symptoms and signs they should _ to what symptoms and signs they should be — to what symptoms and signs they should be looking out for in order to be _ should be looking out for in order to be on— should be looking out for in order to be on time if they develop something that might indicate that there _ something that might indicate that there is— something that might indicate that there is a — something that might indicate that there is a blood clotting issue. many— there is a blood clotting issue. many thanks. i now give the floor to tom clarke from itv. do you hear us? we can see you but we don't hear you. can you open up your mike? —— your microphone? 0k, you. can you open up your mike? —— your microphone? ok, let's take another colleague and then we will come back to you if that is ok. next we have joe come back to you if that is ok. next we havejoe barnes. obviously more people have connection problems today... can you talk? you want to ask your question, joe? do you hear us? obviously we have connection problems. i'm sorry for that. i get the message from any journalist that they don't hear us. —— manyjournalists. they don't hear us at all. obviously not. sorry, colleagues, we are looking into the problem. colleagues, we are looking into the roblem. . , . . problem. have they heard what we have said so _ problem. have they heard what we have said so far— problem. have they heard what we have said so far and _ problem. have they heard what we have said so far and the _ problem. have they heard what we have said so far and the response l problem. have they heard what we l have said so far and the response to the first— have said so far and the response to the first questions? | have said so far and the response to the first questions?— the first questions? i think so. we would have _ the first questions? i think so. we would have heard _ the first questions? i think so. we would have heard before - the first questions? i think so. we would have heard before if- the first questions? i think so. we would have heard before if they i the first questions? i think so. we i would have heard before if they had not heard us, they would have told us. let's try with the next journalist, roland from the standard. i journalist, roland from the standard-— journalist, roland from the standard. ., ., standard. i can hear you and i hope ou can standard. i can hear you and i hope you can hear— standard. i can hear you and i hope you can hear me? _ standard. i can hear you and i hope you can hear me? all— standard. i can hear you and i hope you can hear me? all fine. - standard. i can hear you and i hope you can hear me? all fine. the - you can hear me? all fine. the connection _ you can hear me? all fine. the connection drop _ you can hear me? all fine. the connection drop so _ you can hear me? all fine. the connection drop so i'm - you can hear me? all fine. the connection drop so i'm not - you can hear me? all fine. the| connection drop so i'm not sure you can hear me? all fine. the i connection drop so i'm not sure if this question _ connection drop so i'm not sure if this question has _ connection drop so i'm not sure if this question has been _ connection drop so i'm not sure ifi this question has been addressed, but you _ this question has been addressed, but you mentioned _ this question has been addressed, but you mentioned that _ this question has been addressed, but you mentioned that the - this question has been addressed, i but you mentioned that the evidence you have _ but you mentioned that the evidence you have at — but you mentioned that the evidence you have at the — but you mentioned that the evidence you have at the moment _ but you mentioned that the evidence you have at the moment is— but you mentioned that the evidence you have at the moment is not- you have at the moment is not sufficient — you have at the moment is not sufficient to— you have at the moment is not sufficient to conclude - you have at the moment is not sufficient to conclude with - sufficient to conclude with certainty _ sufficient to conclude with certainty whether - sufficient to conclude with certainty whether these i sufficient to conclude with - certainty whether these adverse events _ certainty whether these adverse events are — certainty whether these adverse events are caused _ certainty whether these adverse events are caused by _ certainty whether these adverse events are caused by the - certainty whether these adverse i events are caused by the vaccine, these _ events are caused by the vaccine, these rare — events are caused by the vaccine, these rare adverse _ events are caused by the vaccine, these rare adverse events, - events are caused by the vaccine, these rare adverse events, but. events are caused by the vaccine, i these rare adverse events, but could they be _ these rare adverse events, but could they be caused — these rare adverse events, but could they be caused by— these rare adverse events, but could they be caused by something - these rare adverse events, but could they be caused by something else i they be caused by something else like acute — they be caused by something else like acute infection _ they be caused by something else like acute infection and _ they be caused by something else like acute infection and which - they be caused by something else. like acute infection and which other scenarios _ like acute infection and which other scenarios are — like acute infection and which other scenarios are you _ like acute infection and which other scenarios are you looking _ like acute infection and which other scenarios are you looking into - like acute infection and which other scenarios are you looking into with| scenarios are you looking into with regards _ scenarios are you looking into with regards to — scenarios are you looking into with regards to factors _ scenarios are you looking into with regards to factors that _ scenarios are you looking into with regards to factors that may - scenarios are you looking into with regards to factors that may have . regards to factors that may have caused _ regards to factors that may have caused the — regards to factors that may have caused the situations _ regards to factors that may have caused the situations we - regards to factors that may have caused the situations we have i regards to factors that may have - caused the situations we have seen? many— caused the situations we have seen? many thanks — caused the situations we have seen? many thanks. doctor— caused the situations we have seen? many thanks. doctor strauss? - caused the situations we have seen? many thanks. doctor strauss? thankj many thanks. doctor strauss? thank ou. we many thanks. doctor strauss? thank you- we have _ many thanks. doctor strauss? thank you. we have been _ many thanks. doctor strauss? thank you. we have been discussing - many thanks. doctor strauss? thank you. we have been discussing some hypothesis— you. we have been discussing some hypothesis to the skirts dip —— to see what— hypothesis to the skirts dip —— to see what the explanation could be and as— see what the explanation could be and as we — see what the explanation could be and as we know that covid can be a factor— and as we know that covid can be a factor in _ and as we know that covid can be a factor in thrombosis and people are being _ factor in thrombosis and people are being hospitalised with thrombosis as welt _ being hospitalised with thrombosis as welt it — being hospitalised with thrombosis as well. it might be that that might have played a role but for the moment— have played a role but for the moment we still feel that we see sufficient — moment we still feel that we see sufficient information to include a warning _ sufficient information to include a warning in— sufficient information to include a warning in the product information. we will— warning in the product information. we will further investigate with the scientific— we will further investigate with the scientific advisory group with additional studies and maybe my colleague would like to highlight the other studies that we are planning, the other investigations that might provide a more definite answer~ _ that might provide a more definite answer. , that might provide a more definite answer. ._ , , ., that might provide a more definite answer. , , ., answer. peter, maybe you can complete? — answer. peter, maybe you can complete? thank _ answer. peter, maybe you can complete? thank you - answer. peter, maybe you can complete? thank you very - answer. peter, maybe you can l complete? thank you very much indeed. this _ complete? thank you very much indeed. this is _ complete? thank you very much indeed. this is an _ complete? thank you very much indeed. this is an important- complete? thank you very much i indeed. this is an important safety review— indeed. this is an important safety review and — indeed. this is an important safety review and we need to make sure the safety _ review and we need to make sure the safety review continues and that we continue _ safety review continues and that we continue to — safety review continues and that we continue to be driven by science and have a _ continue to be driven by science and have a fast— continue to be driven by science and have a fast but robust evaluation. further— have a fast but robust evaluation. further evaluation will include additional expert advice and will include — additional expert advice and will include using epidemiological studies, _ include using epidemiological studies, studies using health care data from — studies, studies using health care data from the real world. we can use that to _ data from the real world. we can use that to look— data from the real world. we can use that to look at a population level as to _ that to look at a population level as to what — that to look at a population level as to what the levels of thrombosis are and _ as to what the levels of thrombosis are and we — as to what the levels of thrombosis are and we can also look at laboratory tests to see whether there _ laboratory tests to see whether there is — laboratory tests to see whether there is anything in particular about— there is anything in particular about these patients that are getting — about these patients that are getting the unusual blood clots which _ getting the unusual blood clots which might suggest or help us to understand the mechanism in which the clots _ understand the mechanism in which the clots are occurring. many thanks for those explanations. _ the clots are occurring. many thanks for those explanations. we - the clots are occurring. many thanks for those explanations. we now - the clots are occurring. many thanks| for those explanations. we now have a jenny hill from the bbc. ——jenny hill. a jenny hill from the bbc. -- jenny hill. ., , ., ., hill. from your initial investigations, - hill. from your initial investigations, is - hill. from your initial. investigations, is there hill. from your initial- investigations, is there a suggestion— investigations, is there a suggestion so— investigations, is there a suggestion so far- investigations, is there a suggestion so far that. investigations, is there a - suggestion so far that specific groups— suggestion so far that specific groups of— suggestion so far that specific groups of people _ suggestion so far that specific groups of people might- suggestion so far that specific groups of people might be - suggestion so far that specific- groups of people might be considered to be at— groups of people might be considered to be at greater— groups of people might be considered to be at greater risk _ groups of people might be considered to be at greater risk of _ groups of people might be considered to be at greater risk of thrombosis - to be at greater risk of thrombosis events? _ to be at greater risk of thrombosis events? ., ,, ., , to be at greater risk of thrombosis events?_ thank i to be at greater risk of thrombosis l events?_ thank you. events? doctor strauss? thank you. the review — events? doctor strauss? thank you. the review of _ events? doctor strauss? thank you. the review of the _ events? doctor strauss? thank you. the review of the cases _ events? doctor strauss? thank you. the review of the cases of _ the review of the cases of thrombosis combined has showed a predominance in some groups and notably— predominance in some groups and notably in — predominance in some groups and notably in women and younger women of younger— notably in women and younger women of younger age, but at the moment it is still— of younger age, but at the moment it is still rather — of younger age, but at the moment it is still rather premature to conclude on a very specific group because — conclude on a very specific group because the background risk of thrombosis may be different in this group _ thrombosis may be different in this group but _ thrombosis may be different in this group but it may also be the case that more — group but it may also be the case that more people have been vaccinated in this specific group. for example, reflecting a predominance of younger women, we know that _ predominance of younger women, we know that in — predominance of younger women, we know that in the different member states— know that in the different member states different vaccination campaigns have been going on, so the potential— campaigns have been going on, so the potential for different risk levels is being — potential for different risk levels is being part of the further evaluation i highlighted before, and if this— evaluation i highlighted before, and if this is— evaluation i highlighted before, and if this is identified they will be further— if this is identified they will be further communicated.- if this is identified they will be further communicated. many thanks. now we have — further communicated. many thanks. now we have another _ further communicated. many thanks. now we have another question, - further communicated. many thanks. now we have another question, from j now we have another question, from norway. now we have another question, from norwa . ., ., ., i. now we have another question, from norwa. ., ., ,, norway. hello. how do you assess toda 's norway. hello. how do you assess today's report _ norway. hello. how do you assess today's report from _ norway. hello. how do you assess today's report from oslo _ norway. hello. how do you assess| today's report from oslo university hospital. _ today's report from oslo university hospital, have— today's report from oslo university hospital, have you _ today's report from oslo university hospital, have you taken _ today's report from oslo university hospital, have you taken that - today's report from oslo university hospital, have you taken that intoi hospital, have you taken that into account? — hospital, have you taken that into account? ., ,, ., ,, hospital, have you taken that into account?_ well, i hospital, have you taken that into | account?_ well, we account? doctor strauss. well, we have assessed _ account? doctor strauss. well, we have assessed everything - account? doctor strauss. well, we have assessed everything that - account? doctor strauss. well, we have assessed everything that was available _ have assessed everything that was available to us until yesterday because — available to us until yesterday because we have of course a report available _ because we have of course a report available for everyone to discuss, so if _ available for everyone to discuss, so if a _ available for everyone to discuss, so if a report came out today that has not _ so if a report came out today that has not been included but what has been _ has not been included but what has been included is the specific cases that we _ been included is the specific cases that we have received from norway and these — that we have received from norway and these have been discussed in depth _ and these have been discussed in depth and — and these have been discussed in depth and also a norwegian representative is part of the risk assessment committee and so in that respect _ assessment committee and so in that respect we _ assessment committee and so in that respect we have taken everything on board _ respect we have taken everything on board but— respect we have taken everything on board but if— respect we have taken everything on board but if there is a study that has been — board but if there is a study that has been published to date we have not taken _ has been published to date we have not taken that on board yet. —— today~ — not taken that on board yet. —— today but _ not taken that on board yet. —— today. but it will be part of our continuous _ today. but it will be part of our continuous monitoring of these issues — continuous monitoring of these issues and we will need to come back to these _ issues and we will need to come back to these issues like we highlighted before, _ to these issues like we highlighted before, anyway, so this is a preliminary conclusion on this specific— preliminary conclusion on this specific case, so it will be part of our further— specific case, so it will be part of our further research, for sure. thank— our further research, for sure. thank you _ our further research, for sure. thank you-— our further research, for sure. thank ou. , . . our further research, for sure. thank ou. , ., . ., thank you. many thanks. we can now no to tom thank you. many thanks. we can now go to tom clarke _ thank you. many thanks. we can now go to tom clarke from _ thank you. many thanks. we can now go to tom clarke from itv. _ thank you. many thanks. we can now go to tom clarke from itv. hello. - go to tom clarke from itv. hello. thanks for— go to tom clarke from itv. hello. thanks for coming _ go to tom clarke from itv. hello. thanks for coming back _ go to tom clarke from itv. hello. thanks for coming back to - go to tom clarke from itv. hello. thanks for coming back to me. i go to tom clarke from itv. hello. | thanks for coming back to me. two questions. — thanks for coming back to me. two questions. you _ thanks for coming back to me. two questions, you mentioned - thanks for coming back to me. two questions, you mentioned you - thanks for coming back to me. two questions, you mentioned you hadl thanks for coming back to me. two l questions, you mentioned you had 18 cases— questions, you mentioned you had 18 cases of— questions, you mentioned you had 18 cases of cbs— questions, you mentioned you had 18 cases of cbs t— questions, you mentioned you had 18 cases of cbs t and _ questions, you mentioned you had 18 cases of cbs t and seven _ questions, you mentioned you had 18 cases of cbs t and seven cases - questions, you mentioned you had 18 cases of cbs t and seven cases of- cases of cbs t and seven cases of another— cases of cbs t and seven cases of another phenomenon— cases of cbs t and seven cases of another phenomenon i— cases of cbs t and seven cases of another phenomenon i did - cases of cbs t and seven cases of another phenomenon i did not. cases of cbs t and seven cases of. another phenomenon i did not quite follow— another phenomenon i did not quite follow your— another phenomenon i did not quite follow your description, _ another phenomenon i did not quite follow your description, can - another phenomenon i did not quite follow your description, can you - follow your description, can you give _ follow your description, can you give a _ follow your description, can you give a bit — follow your description, can you give a bit of— follow your description, can you give a bit of clarification - follow your description, can you give a bit of clarification on - follow your description, can you i give a bit of clarification on that? secondly. — give a bit of clarification on that? secondly, can— give a bit of clarification on that? secondly, can you _ give a bit of clarification on that? secondly, can you explain - give a bit of clarification on that? secondly, can you explain why. give a bit of clarification on that? l secondly, can you explain why we have _ secondly, can you explain why we have seen— secondly, can you explain why we have seen significantly _ secondly, can you explain why we have seen significantly more - secondly, can you explain why we i have seen significantly more cases of these _ have seen significantly more cases of these events— have seen significantly more cases of these events in _ have seen significantly more cases of these events in eu _ have seen significantly more cases of these events in eu countries - of these events in eu countries compared _ of these events in eu countries compared to— of these events in eu countries compared to in— of these events in eu countries compared to in the _ of these events in eu countries compared to in the uk- of these events in eu countries compared to in the uk where l of these events in eu countries. compared to in the uk where we of these events in eu countries - compared to in the uk where we only have five _ compared to in the uk where we only have five reported _ compared to in the uk where we only have five reported cases _ compared to in the uk where we only have five reported cases of— compared to in the uk where we only have five reported cases of cbs - compared to in the uk where we only have five reported cases of cbs t- have five reported cases of cbs t even _ have five reported cases of cbs t even though _ have five reported cases of cbs t even though twice _ have five reported cases of cbs t even though twice as _ have five reported cases of cbs t even though twice as many- have five reported cases of cbs t| even though twice as many doses have five reported cases of cbs t. even though twice as many doses of astrazeneca — even though twice as many doses of astrazeneca vaccine _ even though twice as many doses of astrazeneca vaccine have _ even though twice as many doses of astrazeneca vaccine have been - astrazeneca vaccine have been distributed _ astrazeneca vaccine have been distributed in _ astrazeneca vaccine have been distributed in the _ astrazeneca vaccine have been distributed in the uk? - astrazeneca vaccine have been distributed in the uk? studio: journalists _ distributed in the uk? studio: journalists asking _ distributed in the uk? studio: journalists asking questions . distributed in the uk? studio: journalists asking questions of| distributed in the uk? studio: i journalists asking questions of the committee at the head of the ema which has roots in the last few minutes that there is a clear scientific conclusion that the astrazeneca vaccine is safe and effective. —— ruled. they have not found any formal links with the blood clots and they say any potential risk from the vaccine is completely outweighed by the benefits in terms of fighting covid—19, so the european regulator medicines agency making it clear that the astrazeneca vaccine is safe to use but they will be adding a warning for doctors and medical practitioners across the eu, to raise awareness within customers and patients who may get the vaccine, that their potentially might be issues, but as far as they are concerned there is no problem with the oxford astrazeneca vaccine. more on that when we get it. now it's time for a look at the weather with tomasz schafernaker. hello. fairly quiet on the weather front right now, broadly speaking, not an awful lot of change expected over the next few days. for many of us, fairly cloudy, a bit of sunshine, may be one or two spots of rain and also pretty chilly. the clouds are coming in from the north, a fairly chilly direction, so hence it is not particularly warm, but where the clouds break, and a bit of sunshine develops, it can actually feel pleasant enough. you can see some rain through this evening and overnight when some of that thick cloud drifts off the north sea, that is anywhere from eastern parts of england down towards central southern england. frost—free tonight, around three degrees in glasgow, eight degrees in london, and then tomorrow we do it all over again. again, some spots of rain where the cloud is thicker, however notice it turns sunnier in east midlands and the south—east in the afternoon, slightly drier air coming off off the continent. goodbye. met for priority groups, despite a drop in vaccine supply in april. there will be no weeks in april with no first doses. there will be no cancelled appointments as a result of supply issues. second doses will go ahead as planned. it's as the european medicines regulator says the astrazeneca jab is "safe and effective" after many eu countries paused its roll out over possible blood clots. the uk medicines regulator also says there's no evidence that the astrazeneca vaccine caused blood clots found in five people in the uk.

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