It is understood that the Perth-born actor passed away at the weekend.
The on-screen star left River City in 2018 due to a battle with MDS, otherwise known as Myelodysplastic syndromes - a rare type of blood cancer that causes a person's bone marrow to stop producing healthy blood cells.
Gray, who played Pete Galloway in BBC's River City was also seen on-screen as "Chancer" in 1987 sitcom City Lights.
Outwith acting, he was recognised for his work in pantomime, usually co-writing the script often alongside other former City Lights cast members.
Gray's former colleagues have since paid him heartfelt tributes to him, with BBC Scotland Director Steve Carson describing him as "one of the kindest people" to work with in production.