The analysis, published in
Nature Scientific Reports, is the first of its kind to investigate air pollution’s effects at the single cell level and to simultaneously focus on both the cardiovascular and immune systems in children.
The research confirms previous research that bad air can alter gene regulation in a way that may affect long-term health—a finding that could change the way medical experts and parents think about the air children breathe, and inform clinical interventions for those exposed to chronic elevated air pollution.
“I think this is compelling enough for a pediatrician to say that we have evidence air pollution causes changes in the immune and cardiovascular system associated not only with asthma and respiratory diseases, as has been shown before,” says lead author Mary Prunicki, director of air pollution and health research at Stanford University’s Sean N. Parker Center for Allergy & Asthma Research.