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Hoth Therapeutics' HT-003 Shows Anti-inflammatory Benefits, Hoth to Expand Drug Development to Include Treatment of Inflammatory Bowel Diseases (IBDs)

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NEW YORK, Feb. 18, 2021 /PRNewswire/ Hoth Therapeutics, Inc. (NASDAQ: HOTH), a biopharmaceutical company, today announced that it intends to expand the development of the HT-003 active pharmaceutical ingredient (API) to pursue a new indication for the treatment of inflammatory bowel diseases (IBDs), including Crohn s disease and ulcerative colitis. Hoth executed an option agreement with Isoprene Pharmaceuticals, Inc. ( Isoprene ) to investigate the potential for the HT-003 API as an IBD therapeutic. Isoprene is a University of Maryland, Baltimore New Venture Initiative start-up company.
IBDs represent a large health burden in the United States, affecting approximately 3 million adults age 18 years and older that continues to increase each year. ....

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Hoth Therapeutics Scientific Advisory Board Member, Michael Peters, Ph.D., Publishes Whitepaper Regarding COVID-19 SARS-CoV-2 in bioRxiv

Press release content from PR Newswire. The AP news staff was not involved in its creation. ....

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Hoth Therapeutics Partners with Camargo Pharmaceutical Services for the HT-001 IND, a Treatment for Cancer Patients

Hoth Therapeutics, Inc. (NASDAQ: HOTH), a biopharmaceutical company, today announced that it has signed an agreement with Camargo Pharmaceutical Services to facilitate the writing and submission of the Investigational New Drug application for HT-001 topical product to the U.S. Food and Drug Administration for initiating the first clinical trial. ....

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Hoth Therapeutics Provides Operational Update on Novel Therapeutic Pipeline

Hoth Therapeutics Provides Operational Update on Novel Therapeutic Pipeline
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NEW YORK, Feb. 2, 2021 /PRNewswire/ Hoth Therapeutics, Inc. (NASDAQ: HOTH), a biopharmaceutical company today is providing shareholders with an update on its pipeline of novel therapeutics targeting dermatological, COVID-19 and support care indications.
Drug Pipeline Highlights:
HT-001: Granted Pre-IND meeting with FDA with responses targeted for February 22, 2021
HT-003: Received positive preclinical mechanism of action date for acne treatment and renewal of the preclinical research plan
HT-004: Key proof-of-concept animal model data expected in Q2 2021
Mr. Robb Knie, Chief Executive Officer of Hoth, commented, Hoth s entire pipeline of innovative novel therapeutics have made significant progress throughout their developmental process over the course of the last year. During that time, we have been able ....

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Hoth Therapeutics Expands Research Collaboration Agreement with Weill Cornell Medicine to Continue the Advancement of HT-003 for Acne Treatment Research

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NEW YORK, Jan. 28, 2021 /PRNewswire/ Hoth Therapeutics, Inc. (Nasdaq: HOTH) ( HOTH or the Company ), a biopharmaceutical company, today announced extending a research collaboration agreement with Weill Cornell Medicine to continue investigating the therapeutic mechanism of action and safety of HT-003, a novel retinoic acid metabolism blocking agent (RAMBA), for the treatment of acne. The 1-year agreement extension is based on positive results generated from the prior research agreement that support a therapeutic effect of HT-003 in key signaling pathways contributing to the development of acne.
The extended research collaboration will expand the scope of investigation to further understand the therapeutic mechanism of HT-003 for treatment of acne and other inflammatory skin diseases. The research will also explore safety of HT-003 in murine models. Dr. Jonathan Zippin, M.D., Ph.D., FAAD, Associate Professor of Dermatology at ....

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