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Loss of anti-tumor protein may cause resistance to certain cancer therapies

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HERSHEY, Pa. The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers. They said that testing cancers for the presence of this protein may help clinicians identify patients who may be resistant to or relapse when treated with the therapy.
Epidermal growth factor receptor (EGFR) is a protein that plays a role in cell division and survival signaling and is active in skin, bladder, esophageal, lung, liver, pancreatic, colon, and head and neck cancers. Patients with high amounts of this protein in their tumors tend to have a poor prognosis. EGFR-targeting therapies are used in clinical practice and are often initially effective in many patients. However, some patients are resistant to the therapy and many who were initially responsive to treatment relapse within a year. ....

United States , Mary Landmesser , Wesley Raup Konsavage , Heather Lehman , Penn State Cancer Institute , Penn State College Of Medicine , Drug Administration , Department Of Pathology Researcher , Program Project Award , Research Scholar Grant , Development Award , Millersville University , Highmark Community Health Reinvestment Grant , American Cancer Society , Penn State College , Pathology Researcher Initiated Grant , Highmark Community Health Reinvestment , ஒன்றுபட்டது மாநிலங்களில் , வெஸ்லி ராப் கொன்ஸவாகே , ஹீத்தர் லெஹ்மன் , பென் நிலை புற்றுநோய் நிறுவனம் , பென் நிலை கல்லூரி ஆஃப் மருந்து , துறை ஆஃப் நோயியல் ஆராய்ச்சியாளர் , ப்ரோக்ர்யாம் ப்ராஜெக்ட் விருது , ஆராய்ச்சி அறிஞர் மானியம் , வளர்ச்சி விருது ,

Manitoba doctor recognized for passionate health promotion - CHVNRadio: Southern Manitoba's hub for local and Christian news, and adult contemporary Christian programming.

Winkler-based physician Dr. Heather Lehmann. (Supplied)
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A Manitoba doctor is being recognized for her passionate promotion of health.
Winkler-based physician Dr. Heather Lehmann, says she was shocked to learn she d earned the 2020 Health or Safety Promotion Award by Doctors Manitoba.
Nominated by her colleague, Dr. Thompson, Lehmann says that in itself was a huge honour.
The appreciation that I felt with that was impressive, she noted.
It s a bit funny to me because I think that as a family physician, health promotion is basically our bread and butter, it s a huge part of what we do, says Lehmann. ....

Heather Lehmann , Health Or Safety Promotion Award , Cw Wiebe Medical Centre , Safety Promotion Award , Medical Centre , ஹீத்தர் லெஹ்மன் , ஆரோக்கியம் அல்லது பாதுகாப்பு ப்ரமோஶந் விருது , Cw விஎபே மருத்துவ மையம் , பாதுகாப்பு ப்ரமோஶந் விருது , மருத்துவ மையம் ,