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Virus nucleocapsid protein is a prime target for disease-fighting interventions The virus s nucleocapsid protein is a prime target for disease-fighting interventions. April 22, 2021 Researchers at Oregon State University have taken a key step toward new drugs and vaccines for combating COVID-19 with a detailed biophysical study of one protein s interactions with the SARS-CoV-2 genetic material; SARS CoV-2 is the virus that causes COVID-19. A U.S. National Science Foundation grant supported the research. The virus nucleocapsid protein, or N protein, has multiple functions, including packaging the RNA genome and interacting with other structural proteins during virion assembly. The N protein has critical roles in the coronavirus infection cycle and, because it mutates at a comparatively slow pace, drugs and vaccines targeting the N protein could be highly effective for longer periods of time, making them less susceptible to resistance.

Elisar barbarManju hingoraniHeather masson forsytheResearch newsDivision of molecularResearchers at oregon state universityA us national science foundationOregon state universityScience foundationBiophysical journalCellular biosciencesமஞ்சு ஹிங்கோரணிஹீத்தர் மாஸன் ஃபார்‌ஸைத்ஆராய்ச்சி செய்திபிரிவு ஆஃப் மூலக்கூறுஆராய்ச்சியாளர்கள் இல் ஓரிகந் நிலை பல்கலைக்கழகம்