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Molecule derived from tarantula venom may help relieve chronic IBS pain For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic or long-term abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study in ACS Pharmacology & Translational Science, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain. The sensation of pain originates in electrical signals carried from the body to the brain by cells called neurons. Tiny channels in the surfaces of neurons help them transmit these signals by allowing positively charged sodium ions to pass into the cell. There are numerous types of sodium channels, and some pain-killing drugs work by blocking them. However, existing treatments interfere with channels indiscriminately and can onl

Glenn kingStuart brierleyEmily hendersonUniversity of queenslandUs national institutes of healthAustralian research councilAustralian national healthResearch councilTranslational scienceMedical research councilக்ளென் கிங்ஸ்டூவர்ட் பிரையர்லிஎமிலி ஹென்டர்சன்பல்கலைக்கழகம் ஆஃப் குயின்ஸ்லாந்துஎங்களுக்கு தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம்ஆஸ்திரேலிய ஆராய்ச்சி சபை