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TGen looks beyond COVID-19 as it advances pathogen sequencing

TGen looks beyond COVID-19 as it advances pathogen sequencing
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Like priming a pump, cells damaged by chronic lung disease can result in severe COVID

Like priming a pump, cells damaged by chronic lung disease can result in severe COVID
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

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TGen identifies gene that could help prevent or delay onset of Alzheimer's disease

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PHOENIX, Ariz. April 13, 2021 Findings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that increasing expression of a gene known as ABCC1 could not only reduce the deposition of a hard plaque in the brain that leads to Alzheimer s disease, but might also prevent or delay this memory-robbing disease from developing.
ABCC1, also known as MRP1, has previously been shown in laboratory models to remove a plaque-forming protein known as amyloid beta (Abeta) from specialized endothelial cells that surround and protect the brain and cerebral spinal cord. Building on previous studies, TGen conducted a series of pre-clinical genomic laboratory experiments. Results suggest that ABCC1 not only could export Abeta out of the brain, but that increasing the expression of ABCC1 could reduce Abeta production, thus preventing, or delaying, the onset of Alzheimer s. ....

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New study predicts changing Lyme disease habitat across the West Coast

New study predicts changing Lyme disease habitat across the West Coast
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TGen seeks help from Arizona dog and cat owners for COVID-19 study

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IMAGE: Hayley Yaglom, TGen genomic epidemiologist and lead researcher on a project to test pets for COVID-19, takes a blood sample from a dog.
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Credit: Photo: Courtesy of TGen.
PHOENIX, Ariz. March 10, 2021 The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, announced today the start a new scientific study: Testing pets of those Arizonans who have contracted COVID-19.
No pets will be harmed during this study as all sample collections will be performed by trained veterinary staff. Among the more than 120 pets that have tested positive nationwide, there is no evidence suggesting that pets can spread the virus to humans. ....

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