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Our Immune System Links the Blood-Brain Barrier to Schizophrenia

A genetic condition known as 22q.11.2 deletion syndrome is associated with an increased risk of schizophrenia. A Penn Vet-led team found that a leaky blood-brain barrier, allowing inappropriate immune involvement in the central nervous system, may contribute to this or perhaps other neuropsychiatric conditions. Credit: Jorge Iván Alvarez
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Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation at least when all is functioning normally.
That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led by researchers from the School of Veterinary Medicine, Perelman School of Medicine, and Children s Hospital of Philadelphia (CHOP). In these individuals, a more permissive barrier appears to allow the immune system to get improperly involved in the central nervous system, the researchers showed. The inflamma ....

United States , Stewart Anderson , Alexis Crockett , Vet School , School Of Veterinary Medicine , Perelman School Of Medicine , Veterinary Medicine , Perelman School , Penn Vet , ஒன்றுபட்டது மாநிலங்களில் , ஸ்டீவர்ட் ஆண்டர்சன் , அலெக்சிஸ் குரோக்கெட் , கால்நடை பள்ளி , பள்ளி ஆஃப் கால்நடை மருந்து , பெரல்மேன் பள்ளி ஆஃப் மருந்து , கால்நடை மருந்து , பெரல்மேன் பள்ளி , பென் கால்நடை ,

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Blood-brain barrier and its effect on the immune system play a role in schizophrenia
Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation at least when all is functioning normally.
That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led by researchers from the School of Veterinary Medicine, Perelman School of Medicine, and Children s Hospital of Philadelphia (CHOP).
In these individuals, a more permissive barrier appears to allow the immune system to get improperly involved in the central nervous system, the researchers showed. The inflammation that arises likely contributes to the clinical manifestations of neuropsychiatric conditions. ....

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The immune link between a leaky blood-brain barrier and schizophrenia

The immune link between a leaky blood-brain barrier and schizophrenia
upenn.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from upenn.edu Daily Mail and Mail on Sunday newspapers.

United States , University Of Pennsylvania , Alexism Crockett , Hania Kebir , Richa Kapoor , Raquel Gur , Seank Ryan , James Gesualdi , Donna Mcdonald Mcginn , Stewart Anderson , Elaine Zackai , Nickole Kanyuch , Angela Viaene , Guadalupe Ceja , Alexis Crockett , Adriana Hern , Department Of Pathobiology , Vet School , University Of Pennsylvania School Veterinary Medicine , School Of Veterinary Medicine , Perelman School Of Medicine , Veterinary Medicine , Perelman School , Penn Vet , Caroline Canning , Pennsylvania School ,

Court sinks dream of $1.6bn tourism mecca

Court sinks dream of $1.6bn tourism mecca
A Federal Court ban imposed on the director of besieged finance outfit Mayfair 101 effectively leaves in doubt a $1.6bn tourism vision.
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by Peter Carruthers
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A FEDERAL Court ban imposed on the director of besieged finance outfit Mayfair 101 effectively leaves in doubt a $1.6bn tourism vision for Mission Beach and Dunk Island.
On Monday Mayfair 101 founder James Mawhinney was banned from advertising investments and accepting funds from any financial product for 20 years.
And assets secured through Mayfair products can t be transferred out of the country.
The decision was a final blow to the Mayfair founder following an Australian Securities and Investments Commission move to shut down investment products found by the court to mislead and deceive mum and dad investors lured by the promise of security claimed to be simila ....

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The immune link between a leaky blood-brain barrier and schizophrenia

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IMAGE: A genetic condition known as 22q.11.2 deletion syndrome is associated with an increased risk of schizophrenia. A Penn Vet-led team found that a leaky blood-brain barrier, allowing inappropriate immune involvement.
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Credit: Courtesy of Jorge Iván Alvarez
Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation at least when all is functioning normally.
That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led by researchers from the School of Veterinary Medicine, Perelman School of Medicine, and Children s Hospital of Philadelphia (CHOP). In these individuals, a more permissive barrier appears to allow the immune system to get improperly involved in the central nervous system, the researchers showed. The inflammation that arises likely contributes to the clinical manifestati ....

United States , University Of Pennsylvania , Penn School , Alexism Crockett , Hania Kebir , Raquel Gur , Richa Kapoor , Seank Ryan , James Gesualdi , Donna Mcdonald Mcginn , Stewart Anderson , Elaine Zackai , Nickole Kanyuch , Angela Viaene , Alexis Crockett , Guadalupe Ceja , Adriana Hern , University Of Pennsylvania School Veterinary Medicine , National Institutes Of Health , School Of Veterinary Medicine , Perelman School Of Medicine , Research For The Department Of Child , Department Of Pathobiology , Vet School , Upenn School Of Veterinary Medicine , Lifespan Brain Institute ,