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MD Anderson researchers present new findings in targeted and combination therapies at 2021 ASCO Annual Meeting


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MD Anderson researchers present new findings in targeted and combination therapies at 2021 ASCO Annual Meeting
Several Phase II clinical trials conducted by researchers from The University of Texas MD Anderson Cancer Center show promising results for patients with melanoma, breast cancer, HER2-positive tumors and ovarian cancer. The results of these studies, which will be presented at the virtual 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, highlight new advances in drug therapy research to improve patient outcomes.
Combination therapy of nivolumab and relatlimab before and after surgery is effective against melanoma (Abstract #9502)
In a Phase II study, MD Anderson researchers showed that a regimen of neoadjuvant and adjuvant treatment with checkpoint inhibitors nivolumab, a PD-1 inhibitor, and relatlimab, a LAG-3 inhibitor, was safe and effective in patients with resectable clinical stage III melanoma. ....

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Karyopharm Announces XPOVIO® (selinexor) Data to be Presented at the 2021 American Society of Clinical Oncology Annual Meeting


Karyopharm Announces XPOVIO® (selinexor) Data to be Presented at the 2021 American Society of Clinical Oncology Annual Meeting
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NEWTON, Mass., May 19, 2021 /PRNewswire/  Karyopharm Therapeutics Inc. (Nasdaq:KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that sixteen abstracts have been selected for virtual presentation, including one oral presentation, at the upcoming 2021 American Society of Clinical Oncology (ASCO) Annual Meeting taking place June 4-8, 2021.
Key abstracts to be presented at the meeting will feature clinical data for XPOVIO® (selinexor), the Company s first in class, oral Selective Inhibitor of Nuclear Export (SINE) compound, including: (i) multiple new subgroup analyses from the pivotal Phase 3 BOSTON study, including data results evaluating XPOVIO treatment for patients over the age of 65 years old and patients with RAS-mutated mul ....

United States , University Hospital , Xavier Leleu , Christopherj Walker , Mike Dolph , Talia Golan , Shannon Westin , Sangmin Lee , Yasaman Demastani , Cesar Serrano , Darrell White , Cristina Gasparetto , Thierry Facon , Yazmin Odia , Sharon Shacham , Selective Inhibitor Of Nuclear Export , Virginia University School Of Medicine Neurology Neurosurgery , American Society Of Clinical Oncology , Weill Cornell Medical College , Selective Inhibitor Of Nuclear , University Hospitals Leuven , Leuven Cancer Institute , Miami Cancer Institute , Karyopharm Selective Inhibitor Of Nuclear Export , Mcgill University , Information Department ,

Mereo BioPharma and Cancer Focus Fund Announce Partnership


Mereo BioPharma and Cancer Focus Fund Announce Partnership for Phase 1b/2 Study of Etigilimab in Clear Cell Ovarian Cancer
Study to be Conducted at The University of Texas MD Anderson Cancer Center
Mereo BioPharma Group plc; Cancer Focus Fund
LONDON, UNITED KINGDOM
LONDON and REDWOOD CITY, Calif. and HOUSTON, Texas, April 30, 2021 (GLOBE NEWSWIRE) Mereo BioPharma Group plc (NASDAQ: MREO) (“Mereo” or the “Company”), a clinical-stage biopharmaceutical company focused on oncology and rare diseases, and Cancer Focus Fund, LP, a unique venture capital fund established in collaboration with The University of Texas MD Anderson Cancer Center (“MD Anderson”) to provide funding and clinical expertise to advance promising cancer therapies, today announced a partnership to evaluate Mereo’s lead anti-TIGIT therapeutic antibody candidate, etigilimab, in clear cell ovarian cancer, a rare cancer that accounts for approximately 5–10% of ....

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