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Scientists identify new therapeutic target for several aggressive cancers


Scientists identify new therapeutic target for several aggressive cancers
A protein in tumor cells could be targeted to treat some types of aggressive cancer including brain, blood, skin, and kidney, new research has shown.
The scientists, from the Wellcome Sanger Institute, University of Cambridge and Harvard University, have identified a protein that plays a key role in transforming normal tissue into cancer, as a possible target for drug development. Inhibiting this protein effectively destroys cancer cells in laboratory models, including in cell lines and mice, while leaving healthy cells unharmed.
The research, published today (4 August 2021) in
Molecular Cell, provides strong evidence that developing drugs that block the RNA-modifying protein known as METTL1 could give people with aggressive brain, blood, skin, and kidney cancers new treatment options. ....

United States , United Kingdom , Harvard University , Richard Gregory , Esteban Orellana , Konstantinos Tzelepis , Emily Henderson , University Of Cambridge , Research Fellow At Boston Children Hospital , Harvard Medical School , Wellcome Sanger Institute , Molecular Cell , Principle Investigator , Boston Children , First Author , Research Fellow , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , ஹார்வர்ட் பல்கலைக்கழகம் , ரிச்சர்ட் கிரெகொரி , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , ஹார்வர்ட் மருத்துவ பள்ளி , வெல்கம் சாங்கர் நிறுவனம் , மூலக்கூறு செல் , ப்ரிந்ஸிபல் புலனாய்வாளர் ,