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Optogenetics used for the first time to help a blind patient see again


Adobe
Somewhere in Paris, in a white room, seated at a white table, a man wearing a headset reminiscent of those worn by VR gamers reached out with his right hand and placed his fingers on a black notebook. This simple motion, which he executed with confidence, was notable for one very important reason: The man had been blind for close to four decades.
What was different now was that as part of a clinical trial, genes had been injected into one of his eyes, causing neurons in the retina to produce a light-sensing protein normally found in the slimy bodies of green algae. When the black goggles he was wearing projected video images of his surroundings as a pulsed light beam onto those now-light-sensitive cells, the neurons fired, and the signal traveled up the optic nerve and into the visual processing center of the brain. The genetically modified neurons had become stand-ins for the photoreceptors he had lost many years before to a genetic disease called retinitis pigmento ....

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Forget Herd Immunity! Winter COVID Surges Will Bring Lockdowns, Travel Bans, Crammed ICUs


Forget Herd Immunity! Winter COVID Surges Will Bring Lockdowns, Travel Bans, Crammed ICUs
On 05/12/21 at 5:00 AM EDT
Zhengshun Tang/Getty
As India descended into a COVID-19 tragedy that dwarfed anything the country had experienced in the pandemic so far, with hospitals inundated, oxygen supplies short and vaccines reportedly being stolen from warehouses, American politicians thousands of miles away were clamoring to end pandemic restrictions.
Representative Jim Jordan railed at Dr. Anthony Fauci in the House chambers, You don t think Americans liberties have been threatened in the last year, Dr. Fauci? They ve been assaulted! Alabama Governor Kay Ivey told Fox News, We have been at this for more than a year now, and we have simply got to move forward. Endless government mandates are not the answer. ....

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NIMH » Questions and Answers for the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) Study — Background


March 2007
A. STEP-BD is the largest, federally-funded treatment study ever conducted for bipolar disorder
1. It is a long-term outpatient study that enrolled 4,360 participants from 22 sites over seven years (1998 to 2005). STEP-BD was designed to find out which treatments, or combinations of treatments, are most effective for treating episodes of depression and mania and for preventing recurrent episodes in people with bipolar disorder. STEP-BD is different from typical clinical trials that test one potential new treatment. It is a broad research program that includes several different studies, each aimed at a different aspect of treatment for the illness.
Multiple treatments, including medications and psychotherapies, currently are available for people with bipolar disorder, but doctors are often uncertain which of these treatments actually work best for specific aspects of the illness. ....

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GT Biopharma Announces the Appointments of Gregory Berk, M.D. to Chief Medical Officer and Jeffrey S. Miller, M.D. to Consulting Chief Scientific Officer


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BEVERLY HILLS, Calif., April 26, 2021 /PRNewswire/ GT Biopharma, Inc. (NASDAQ: GTBP), a clinical stage immuno-oncology company focused on developing innovative therapeutics based on the Company s proprietary natural killer (NK) cell engager, TriKE™ protein biologic technology platform, today announced the appointment of Gregory Berk, M.D., to the position of Chief Medical Officer. Dr. Berk has served as a Director on GT Biopharma s Board since November 2020, and resigns that post in conjunction with his appointment.
The Company is also pleased to announce that Jeffrey S. Miller, M.D., who has supported GT Biopharma as the Company s Consulting Chief Medical Officer since August 2019, will become the Company s Consulting Chief Scientific Officer. Dr. Miller, with his colleagues at the University of Minnesota, is the inventor of the novel TriKE™ technology platform. Dr. Miller will continue his leadership role with respect to ....

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