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Muscles lose their smallest, most basic building blocks after stroke


Muscles lose their smallest, most basic building blocks after stroke
After suffering a stroke, patients often are unable to use the arm on their affected side. Sometimes, they end up holding it close to their body, with the elbow flexed.
In a new study, Northwestern University and Shirley Ryan AbilityLab researchers have discovered that, in an attempt to adapt to this impairment, muscles actually lose sarcomeres their smallest, most basic building blocks.
Stacked end to end (in series) and side to side (in parallel), sarcomeres make up the length and width of muscle fibers. By imaging biceps muscles with three noninvasive methods, the researchers found that stroke patients had fewer sarcomeres along the length of the muscle fiber, resulting in a shorter overall muscle structure. ....

Wendy Murray , Shirley Ryan Abilitylab , Julius Dewald , Amy Adkins , Emily Henderson , Northwestern Mccormick School Of Engineering , Proceedings Of The National Academy Arts , Northwestern University , Northwestern University Feinberg School Of Medicine , National Academy , Mccormick School , Northwestern University Feinberg School , Shirley Ryan , Medical Imaging , வெண்டி முர்ரே , எமிலி ஹென்டர்சன் , வடமேற்கு ம்க்கார்‌மிக் பள்ளி ஆஃப் பொறியியல் , வடமேற்கு பல்கலைக்கழகம் , வடமேற்கு பல்கலைக்கழகம் ஃபைன்பெர்க் பள்ளி ஆஃப் மருந்து , தேசிய கலைக்கழகம் , ம்க்கார்‌மிக் பள்ளி , வடமேற்கு பல்கலைக்கழகம் ஃபைன்பெர்க் பள்ளி , ஷெர்லி ரியான் ,

Muscle's smallest building blocks disappear after stroke