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Drug to Delay T1D Gets Tepid Endorsement by FDA Advisors


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Teplizumab got a reticent thumbs-up from FDA advisors for an indication in delaying progression of at-risk patients to clinical type 1 diabetes (T1D).
The agency s Endocrinologic and Metabolic Drugs Advisory Committee on Thursday voted 10-7 that sufficient evidence of benefit outweighed the risks for this novel biologic.
However, a number on both sides indicated how narrowly they had come to making the opposite decision.
I voted yes but had my finger over the no button for a long time, said Jack Yanovski, MD, PhD, chief of the Section on Growth and Obesity at the National Institute of Child Health and Human Development in Bethesda, Maryland. ....

United States , University Of Pennsylvania , Tufts Medical Center , Marvin Konstam , Erica Brittain , Susan Ellenberg , Eleanor Ramos , Provention Bio , Lauren Wood Heickman , Michael Blaha , Johns Hopkins , Gary Meininger , Jack Yanovski , Vertex Pharmaceuticals , Metabolic Drugs Advisory Committee On , Ut Southwestern Medical Center , Human Development In Bethesda , National Institute Of Child Health , Metabolic Drugs Advisory Committee , National Institute , Child Health , Human Development , James De Lemos , Medical Center , Cytokine Release Syndrome , ஒன்றுபட்டது மாநிலங்களில் ,

Beef Management: grass shortages and thinking about dosing


 
Grass shortages: There is a marked difference in different parts of the country in grass growth.
On some farms there are real issues where farm cover has dropped to a very low level and grass is finding it hard to get going again.
Higher stocked farms have been hit hardest. On some of these farms gates were opened up to allow animals access a larger area to avoid housing.
Some supplementary feed should have been introduced on these farms to try to hold the rotation and keep closing up paddocks behind cattle as they move through them. When grass is eaten at very low covers it takes longer for it to get growing again so that’s why some farms are not seeing any growth. ....

Kieran Mailey , Animal Health Ireland , Health Ireland , Grass Growth , Ground Conditions , Tullamore Farm , Adam Woods , கீரெந் அஞ்சல் , விலங்கு ஆரோக்கியம் ஐயர்ல்யாஂட் , ஆரோக்கியம் ஐயர்ல்யாஂட் , புல் வளர்ச்சி , தரையில் நிபந்தனைகள் , துல்லமோர் பண்ணை , பண்படாமனித இயல்பு வூட்ஸ் ,

Dispensing Station Covers Every Daily Dosing Task


Apr 28 2021 Read 8 Times
Especially in the current pandemic period, laboratory technicians need to automate routine work processes, such as the precise and efficient filling of different dosing media in the laboratory.
Poulten & Graf’s FORTUNA® OPTIMAT® 3 dosing station with one dosing pump and a RS 232 connection interface is ideally suited for this purpose. OPTIMAT dosing pumps are available in seven sizes from 2 ml to 300 ml. Depending on your application any possible intermediate volumes are programmable. Even aggressive liquids, can be easily handled with the OPTIMAT® dosing pumps that are made of high-quality materials such as borosilicate glass and PTFE. The robust FORTUNA® OPTIMAT® 3 is designed to provide years of continuous use in daily operation. And you will certainly find a place for the OPTIMAT® in your laboratory. ....

Poulten Graf ,

Vet medicines meeting ends in chaos


SHARING OPTIONS:
The Irish Farmers Journal understands that the Minister for Agriculture will meet stakeholders in the coming weeks.
A meeting between the Department of Agriculture and the anti-parasitic stakeholder group (APR) ended in chaos last week with widespread condemnation of the lack of progress in finding a solution to the problems set to be created by the looming changes to veterinary medicines dispensing rules.
The current proposals would see all licensed medicines and dosing products requiring a prescription before they can be sold to a farmer from January 2022 onwards.
Secretary general of the Independent Licensed Merchants Association (ILMA) Ian Scott said the APR stakeholder meetings “are a complete charade” and “a clever yet cynical box-ticking exercise on behalf of the Department. ....

Charlie Mcconalogue , Ian Scott , Department Of Agriculture , Merchants Association , Independent Licensed Merchants Association , Irish Farmers Journal , Breeding Health , Minister For Agriculture , Adam Woods , ஈயந் ஸ்காட் , வணிகர்கள் சங்கம் , சுயாதீனமான உரிமம் பெற்றது வணிகர்கள் சங்கம் , ஐரிஷ் விவசாயிகள் இதழ் , இனப்பெருக்க ஆரோக்கியம் , பண்படாமனித இயல்பு வூட்ஸ் ,