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Chemistry Nobel predictions range from free-radical chemistry to MOFs

Chemistry Nobel predictions range from free-radical chemistry to MOFs
chemistryworld.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from chemistryworld.com Daily Mail and Mail on Sunday newspapers.

United States , United Kingdom , Akira Yoshino , Stanford Carolyn Bertozzi , Fraser Stoddart , Robert Langer , Berkeley Omar Yaghi , Clarivate Nobel , Barry Halliwell , Emmanuelle Charpentier , Stanley Whittingham , Peter Schultz , Andrew Smith , Shankar Balasubramanian , Martin Karplus , Stuart Cantrill , Mitsue Sawamoto , David Klenerman , Moderna Covid , John Goodenough , Alfred Nobel , Jennifer Doudna , Scripps Research Institute , University Of California , University Of Tokyo Makoto Fujita , Massachusetts Institute Of Technology ,

Scientists identify existing drugs that may inhibit SARS-CoV-2 virus

Scientists identify existing drugs that may inhibit SARS-CoV-2 virus
The COVID-19 pandemic has caused more than 600,000 deaths in the United States since the start of 2020 and more than 4 million globally. The search for effective treatments against the disease are ongoing, and one hurdle is that SARS-CoV-2, the virus that causes COVID-19, has a number of tricks up its molecular sleeve when it comes to infecting people.
In a recent study published in Nature Communications Biology, researchers from the U.S. Department of Energy s (DOE) Argonne National Laboratory and the University of Chicago identified a way to interfere with a sneaky mechanism the virus uses to prevent a response from an infected person s immune system. ....

United States , Youngchang Kim , Natalia Maltseva , Andrzej Joachimiak , William Jorgensen , Karen Anderson , Emily Henderson , Yale University , Yale Cancer Center , Nature Communications Biology , Us Department Of Energy , American Chemical Society , Office Of Science User Facility At Argonne , Argonne National Laboratory , University Of Chicago , Structural Biology Center , Chemistry Department , Advanced Photon Source , Science User Facility , American Chemical , Sterling Professor , ஒன்றுபட்டது மாநிலங்களில் , வில்லியம் ஜோர்கென்சன் , கரேன் ஆண்டர்சன் , எமிலி ஹென்டர்சன் , யேல் பல்கலைக்கழகம் ,

Yale targets COVID-19 with innovative computational design methods

By Jim Shelton
February 24, 2021
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Yale scientists have developed a new class of antiviral agents that shows promise for creating COVID-19 therapeutics exhibiting particular effectiveness when used in tandem with the drug remdesivir, another antiviral medication approved for use against the virus.
The new compounds are the first potent, drug-like, non-covalent, and non-peptidic inhibitors of the main protease, or enzyme, in SARS-CoV-2 that is crucial for processing essential viral proteins. A study demonstrating the compounds appears in the journal ACS Central Science.
The work is the latest collaboration of Yale researchers William Jorgensen and Karen Anderson, senior co-authors of the study, who use high-level computation and structural biology methods to design compounds that target viral proteins. ....

Farren Isaacs , William Jorgensen , Elizabeth Stone , Mohammad Ghahremanpour , Brett Lindenbach , Scott Miller , Yuka Takeo , Krasimir Spasov , Julian Tirado Rives , Joseph Ippolito , Shuo Zhang , Karen Anderson , Chun Hui Zhang , Shalley Kudalkar , Zhuobin Liang , Maya Deshmukh , Yale University School Of Medicine , Us National Institutes Of Health , Yale Cancer Center , Sterling Professor , Yale Cancer , Additional Yale , Yale University School , Yale University , Press Releases , ஃப்யாரந் ஐஸக்ஸ் ,