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Experts Debate Merits of Dual Therapy for Lupus Nephritis

Brad Rovin, MD, and Richard Furie, MD, discussed the merits of dual therapy with voclosporin or belimumab in lupus nephritis but said response rates leave a lot of room for improvement. ....

New York , United States , Brad Rovin , Richarda Furie , Graciela Alarcon , Pan American League , Drug Administration , University Of Alabama At Birmingham , Ohio State University Wexner Medical Center , Barbara Zucker School , American League , Presented August , Systemic Lupus Erythematosus , Lupus Nephritis , End Stage Renal Disease Esrd , End Stage Renal Disease , Kidney Ureter Bladder , Ub Kidney Ureter Bladder , Immunosuppressive Therapy , Immunosuppressive Agents , Immunosuppressive Drugs , Rug Immunosuppressive , Polyarteritis Nodosa , Eriarteritis Nodosa , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் ,

Personalized Algorithm Helps Guide Rituximab Retreatment

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A personalized algorithm was developed by researchers in England to recommend retreatment with rituximab (Rituxan) among patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, with the intention of preventing relapses while lowering the risks of infection.
In a multivariable analysis of 60 rituximab-treated patients with ANCA-associated vasculitis followed over a decade, predictors of a longer time to relapse were concomitant immunosuppression (HR 0.48, 95% CI 0.24-0.94,
P=0.034), complete response at 6 months (HR 0.24, 95% CI 0.12-0.50,
P ....

Jack Arnold , Nancy Walsh , Regina College In Newport , Leeds Institute Of Rheumatic , Peuropean League Against Rheumatism , Leeds Institute , Birmingham Vasculitis Activity Score , Salve Regina College , League Against , Granulomatosis With Polyangiitis , பலா அர்னால்ட் , நான்சி வால்ஷ் , ரெஜினா கல்லூரி இல் நியூபோர்ட் , லீட்ஸ் நிறுவனம் ஆஃப் வாத , ஐரோப்பிய லீக் எதிராக வாத நோய் , லீட்ஸ் நிறுவனம் , பர்மிங்காம் வாஸ்குலிடிஸ் நடவடிக்கை மதிப்பெண் , சால்வ் ரெஜினா கல்லூரி , லீக் எதிராக ,

SARS-CoV-2 triggers development of new-onset IgG autoantibodies in hospitalized COVID-19 patients

SARS-CoV-2 triggers development of new-onset IgG autoantibodies in hospitalized COVID-19 patients
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), is associated with several clinical features common in autoimmune diseases as myalgias, arthralgias, fatigue, and rashes. COVID-19 patients also exhibit less common autoimmunity manifestations such as myositis, thrombosis, myocarditis, encephalitis, vasculitis, and arthritis.
These observations, coupled with the increasing number of recovered long-COVID patients with post-COVID-19 symptoms, indicate that SARS-CoV-2-related inflammation promotes tissue damage. Prior research has shown that about 50% of hospitalized COVID-19 patients at an academic hospital in Greece had high serum levels of autoantibodies, often associated with thrombosis, rashes, and vasculitis. Also, serum anti-nuclear antibodies (ANAs) were detected in about one-third of the patients. ....

United States , Susha Cheriyedath , New Onset Igg Autoantibodies , Hospitalized Patients , Corona Borealis Studio , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , கொரோனா போரியாலிஸ் ஸ்டுடியோ , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

8 Penyebab Bentol Merah di Kaki dan Cara Mengatasinya

8 Penyebab Bentol Merah di Kaki dan Cara Mengatasinya
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