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Novel Synthesis Method Aids Rapid Testing of Vaccine Strategies against Respiratory Pathogens


Novel Synthesis Method Aids Rapid Testing of Vaccine Strategies against Respiratory Pathogens
Source: Robert Hoetink/Fotolia
January 20, 2021
Scientists in Australia have developed a method for the rapid synthesis of safe vaccines, and say their approach can be used to create and test potential vaccine strategies against respiratory pathogens, including SARS-CoV-2. Headed by Richard Payne, PhD, at the University of Sydney, and Warwick Britton, PhD, at the Centenary Institute, the research team demonstrated application of their method with the development of a synthetic, self-adjuvanted protein vaccine against tuberculosis (TB), which generated a powerful protective immune response in mice.
“Tuberculosis infects 10 million and kills more than 1.4 million people every year,” said Anneliese Ashhurst, PhD, from the University of Sydney, who is joint first author of the team’s published paper in ....

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Novel Inhaled Vaccine for Tuberculosis Shows Strong Immune Response in Mice


New method to assist fast-tracking of vaccines for pre-clinical tests
Scientists in Australia have developed a method for the rapid synthesis of safe vaccines, an approach that can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes COVID-19.
Led by Professor Richard Payne at the University of Sydney and Professor Warwick Britton at the Centenary Institute, the team has demonstrated application of the method with a new vaccine for use against tuberculosis (TB), which has generated a powerful protective immune response in mice.
Researchers are keen to develop the vaccine strategy further to assist in the rapid pre-clinical testing of new vaccines, particularly for respiratory illnesses. ....

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New Method Tests Vaccine Strategies Against Novel Pathogens


New Method Tests Vaccine Strategies Against Novel Pathogens
by Angela Mohan on 
January 19, 2021 at 11:00 AM
Protein-based immunization method developed by the Australian researchers, can be used to test various vaccine strategies against novel pandemic pathogens including SARS-CoV-2.
The research was led by Professor Richard Payne at the University of Sydney and Professor Warwick Britton at the Centenary Institute. The team has demonstrated application of the method with a new vaccine for use against tuberculosis (TB), which has generated a powerful protective immune response in mice.
Researchers want to identify vaccine strategy to assist in the rapid pre-clinical testing of new vaccines, particularly for respiratory illnesses. ....

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