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Nutrition, companionship reduce pain in mice with sickle cell disease, UCI-led study finds


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Irvine, Calif. Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain.
Finding safe and effective alternatives to opioids is a research priority, especially for patients with sickle cell disease, said Dr. Keith Hoots, director of the Division of Blood Diseases and Resources at the National Heart, Lung, and Blood Institute. It s encouraging to see a dose-response relationship to nutrients and companions in mice, which guides future research about the role foods and friends may have in helping humans manage chronic pain. ....

United States , San Antonio , University Of Texas , Varun Sagi , Rajendra Badgaiyan , Kalpna Gupta , Centers For Disease , University Of California , National Institutes Of Health , University Of Texas Health Science Center , Division Of Blood Diseases , University Of Minnesota , Blood Institute , National Heart , Keith Hoots , Blood Diseases , Scientific Reports , Disease Control , Texas Health Science Center , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , சான் அன்டோனியோ , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் , வருண் சகி , ராஜேந்திரா பட்கையன் , கல்ப்னா குப்தா ,

Enriched diet and companionship can reduce pain in mice with sickle cell disease


Enriched diet and companionship can reduce pain in mice with sickle cell disease
Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain.
Finding safe and effective alternatives to opioids is a research priority, especially for patients with sickle cell disease. It s encouraging to see a dose-response relationship to nutrients and companions in mice, which guides future research about the role foods and friends may have in helping humans manage chronic pain. ....

United States , San Antonio , University Of Texas , Varun Sagi , Rajendra Badgaiyan , Kalpna Gupta , Emily Henderson , Centers For Disease , University Of California , University Of Texas Health Science Center , Division Of Blood Diseases , University Of Minnesota , Blood Institute , National Heart , Keith Hoots , Blood Diseases , Scientific Reports , Disease Control , Texas Health Science Center , ஒன்றுபட்டது மாநிலங்களில் , சான் அன்டோனியோ , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் , வருண் சகி , ராஜேந்திரா பட்கையன் , கல்ப்னா குப்தா , எமிலி ஹென்டர்சன் ,