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First synthetic circuit consists of entirely fast, reversible protein-protein interactions


First synthetic circuit consists of entirely fast, reversible protein-protein interactions
Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.
However, there is often a long lag time between an event such as detecting a molecule and the resulting output, because of the time required for cells to transcribe and translate the necessary genes. MIT synthetic biologists have now developed an alternative approach to designing such circuits, which relies exclusively on fast, reversible protein-protein interactions. ....

Bonnie Berger , Brian Teague , Ron Weiss , Tristan Bepler , Deepak Mishra , Emily Henderson , University Of Wisconsin , Artificial Intelligence Laboratory , Department Of Biological Engineering , Department Of Biochemistry , Study Lead Author , Research Associate , Biological Engineering , Simons Professor , Jim Broach , Molecular Biology , Penn State Hershey Medical , போனி பெர்கர் , பிரையன் டீக் , ரோன் வெயிஸ் , தீபக் மிஸ்ரா , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் விஸ்கான்சின் , செயற்கை உளவுத்துறை ஆய்வகம் , துறை ஆஃப் உயிரியல் பொறியியல் , துறை ஆஃப் உயிர் வேதியியல் ,

Engineers create protein circuits which respond in seconds

Engineers create protein circuits which respond in seconds
theiet.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from theiet.org Daily Mail and Mail on Sunday newspapers.

Ron Weiss , Deepak Mishra , Department Of Biological Engineering , Biological Engineering , Professor Ron Weiss , ரோன் வெயிஸ் , தீபக் மிஸ்ரா , துறை ஆஃப் உயிரியல் பொறியியல் , உயிரியல் பொறியியல் ,

MIT team employs synthetic biology to create 'circuits' that could detect signs of disease

MIT team employs synthetic biology to create 'circuits' that could detect signs of disease
fiercebiotech.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from fiercebiotech.com Daily Mail and Mail on Sunday newspapers.

Ron Weiss , Massachusetts Institute Of Technology , Massachusetts Institute , ரோன் வெயிஸ் , மாசசூசெட்ஸ் நிறுவனம் ஆஃப் தொழில்நுட்பம் , மாசசூசெட்ஸ் நிறுவனம் ,

Synthetic biology circuits can respond within seconds


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Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.
 
However, there is often a long lag time between an event such as detecting a molecule and the resulting output, because of the time required for cells to transcribe and translate the necessary genes. MIT synthetic biologists have now developed an alternative approach to designing such circuits, which relies exclusively on fast, reversible protein-protein interactions. This means that there’s no waiting for genes to be transcribed or translated into proteins, so circuits can be turned on much faster within seconds. ....

Bonnie Berger , Brian Teague , Ron Weiss , Tristan Bepler , Deepak Mishra , National Science Foundation Graduate Research Fellowship Program , Artificial Intelligence Laboratory , Department Of Biological Engineering , Institute For Collaborative Biotechnologies , National Institutes Of Health , National Science Foundation , Department Of Biochemistry , University Of Wisconsin , Us Army Research Office , Energy Research Fellowship , Biological Engineering , Simons Professor , Jim Broach , Molecular Biology , Penn State Hershey Medical , Siebel Scholars Award , Research Fellowship , Collaborative Biotechnologies , Research Office , Integrated Synthetic Biology , National Institutes ,