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Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome


Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome
Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that variants in the SPTBN1 gene can alter neuronal architecture, dramatically affecting their function and leading to a rare, newly defined neurodevelopmental syndrome in children.
Damaris Lorenzo, PhD, assistant professor in the UNC Department of Cell Biology and member of the UNC Neuroscience Center at the UNC School of Medicine, led this research, which was published today in the journal
Nature Genetics. Lorenzo, who is also a member of the UNC Intellectual and Developmental Disabilities Research Center (IDDRC) at the UNC School of Medicine, is the senior author. ....

Sruthi Dontu , Keith Burridge , Deepa Ajit , Emily Henderson , Kathryn Harper , Vann Bennett , Brenda Temple , Keith Breau , Lorena Munoz , Adriana Beltran , Becky Spillmann , Sheryl Moy , Alvaro Beltran , Damaris Lorenzo , Liset Falcon , Simone Afriyie , Reggie Edwards , Richard Cheney , Laura Ranum , Blake Creighton , School Of Medicine , Neuroscience Center , Department Of Cell Biology , Department Of Biochemistry , Department Of Psychiatry , Developmental Disabilities Research Center ,

Is the US headed toward a new housing bubble?


 
The staggering rise of U.S. home prices is forcing thousands of aspiring buyers into grueling, often risky bidding wars, raising questions about whether the torrid housing market could be in a bubble.
For nearly a year, the combination of low mortgage rates, a flood federal stimulus, lockdowns and teleworking  all sparked by the coronavirus pandemic  has fueled a rapid increase in demand for houses.
At the same time, COVID-19 exacerbated an already severe housing shortfall by causing major delays in new home construction and kept some potential sellers on the sidelines because they were afraid to let strangers tour their homes during a pandemic. ....

United States , Jerome Powell , Julio Lopez , Reggie Edwards , Lawrence Yun , Mike Fratantoni , National Association Of Realtors , Mortgage Bankers Association , Federal Reserve , Mortgage Bankers , Frank Wall Street , Reserve Chairman Jerome Powell , Hispanic Americans , National Association , ஒன்றுபட்டது மாநிலங்களில் , ஜெரோம் போவல் , ஜூலியோ லோபஸ் , ரெகி எட்வர்ட்ஸ் , லாரன்ஸ் யுன் , தேசிய சங்கம் ஆஃப் றேஆல்டோர்ச் , அடமானம் வங்கியாளர்கள் சங்கம் , கூட்டாட்சியின் இருப்பு , அடமானம் வங்கியாளர்கள் , வெளிப்படையான சுவர் தெரு , இருப்பு தலைவர் ஜெரோம் போவல் , ஹிஸ்பானிக் அமெரிக்கர்கள் ,