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The NDA of the Novel Anti-PD-1 mAb Serplulimab of Henlius Accepted by NMPA and Proposed to be Granted Priority Review

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SHANGHAI, April 22, 2021 /PRNewswire/ Shanghai Henlius Biotech, Inc. (2696.HK) announced that the New Drug Application (NDA) of serplulimab injection (HLX10), a novel anti-PD-1 monoclonal antibody (mAb), for the treatment of unresectable or metastatic microsatellite instability-high (MSI-H) solid tumors that fail to respond to the standard therapy, has been accepted by the National Medical Products Administration (NMPA) and proposed to be granted priority review. Serplulimab is potentially to be the first anti-PD-1 mAb in MSI-H solid tumors in China. For this indication, patients are screened for specific MSI-H tumor markers, rather than classifying the tumor types, covering a wide range of cancer types. Henlius adopts the Combo+Global development strategy for serplulimab, focusing on indication differentiation and combination therapy, with a total of 10 clinical trials conducted worldwide. ....

United States , Josephl Leach , Wray Mcdermott , Michaelj Overman , Paoloa Asciert , Kalbe Genexine Biologics , Wenjie Zhang , Shukui Qin , Aurelien Marabelle , Prnewswire Shanghai Henlius Biotech Inc , European Union , Cancer Center , National Medical Products Administration , Drug Administration , Henlius Biotech , New Drug Application , Pprofessor Shukui Qin , Nanjing Jinling Hospital , Chief Executive Officer , Genexine Biologics , New Drug Applications , Manufacturing Practice , Cancer Res Clin , Microsatellite Instability High , Deficient Mismatch Repair , Solid Tumors ,

The NDA of the Novel Anti-PD-1 mAb Serplulimab of Henlius Accepted by NMPA and Proposed to be Granted Priority Review

The NDA of the Novel Anti-PD-1 mAb Serplulimab of Henlius Accepted by NMPA and Proposed to be Granted Priority Review
prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.

United States , Josephl Leach , Wray Mcdermott , Michaelj Overman , Paoloa Asciert , Kalbe Genexine Biologics , Wenjie Zhang , Shukui Qin , Aurelien Marabelle , Prnewswire Shanghai Henlius Biotech Inc , European Union , Cancer Center , National Medical Products Administration , Drug Administration , Henlius Biotech , New Drug Application , Pprofessor Shukui Qin , Nanjing Jinling Hospital , Chief Executive Officer , Genexine Biologics , New Drug Applications , Manufacturing Practice , Cancer Res Clin , Microsatellite Instability High , Deficient Mismatch Repair , Solid Tumors ,

Henlius Plans to File the NDA of Novel anti-PD-1 mAb HLX10 for the Treatment of MSI-H Solid Tumours, the Phase 2 Clinical Trial has Met the Primary Endpoint

Henlius Plans to File the NDA of Novel anti-PD-1 mAb HLX10 for the Treatment of MSI-H Solid Tumours, the Phase 2 Clinical Trial has Met the Primary Endpoint
prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.

United States , Josephl Leach , Wray Mcdermott , Michaelj Overman , Paoloa Asciert , Kalbe Genexine Biologics , Shukui Qin , Aurelien Marabelle , Jin Li , Shanghai Henlius Biotech Inc , Hospital Of People Liberation Army , National Drug Products Administration , European Union , Drug Administration , Shanghai Tongji University , Shanghai Henlius Biotech , New Drug Application , Liberation Army , Shanghai East Hospital , Genexine Biologics , New Drug Applications , Manufacturing Practice , Cancer Res Clin , Microsatellite Instability High , Deficient Mismatch Repair , Solid Tumors ,

DUNSHEE, Jeffrey : Acknowledgement notice - Irish Times Family Notices

DUNSHEE, Jeffrey : Acknowledgement notice
DUNSHEE - Jeffrey (Vermont USA and Dublin Ireland). On the first anniversary of his death, February 19, Jeff is very lovingly remembered by his family and friends in Ireland, USA and around the world. Sharen and Margaret would like to thank our family and friends for their support, and for the condolences offered by so many at his funeral. We extend our appreciation to those that travelled from afar, who wrote, and visited. Every message was appreciated beyond measure. To those that made donations to Cancer Trials Ireland, please know that your contributions have made an impact into cancer research efforts here in Ireland. We are grateful for the uplifting service delivered by The Reverend Brigid Spain of The Unitarian Church, to Niall Lawlor, Josh Johnston and The Loreto Ceiliur Choir who provided such memorable music and made the service such a fitting reflection of Jeff’s wonderfully varied and amazing life. We expressly thank Pro ....

United States , Josh Johnston , Michael Keane , Wray Mcdermott , Niall Lawlor , Unitarian Church , Vermont United States , Dublin Ireland , Cancer Trials Ireland , Reverend Brigid Spain , Loreto Ceiliur Choir , Prof Michael Keane , Prof Ray Mcdermott , Cara Ward , Mccabes Pharmacy , ஒன்றுபட்டது மாநிலங்களில் , ஜோஷ் ஜான்ஸ்டன் , மைக்கேல் கீந் , ராய் மக்டர்மட் , நியால் சட்டத்தரணி , யூனிடேரியன் தேவாலயம் , வெர்மான்ட் ஒன்றுபட்டது மாநிலங்களில் , டப்ளின் ஐயர்ல்யாஂட் , புற்றுநோய் சோதனைகள் ஐயர்ல்யாஂட் , பயபக்தியுடன் ப்ரிஜிட் ஸ்பெயின் , ப்ரொஃப் மைக்கேல் கீந் ,

The Queen's Gambit and the myth of the chess genius

“It’s an entire world of just 64 squares. I feel safe in it. I can control it; I can dominate it – and it’s predictable.” In the Netflix miniseries,
The Queen’s Gambit, these are the words that chess prodigy Beth Harmon uses to describe her passion for the game, but I suspect that they also tell us something about the runaway success of this series in the first year of the Covid-19 pandemic.
The seven-episode series was viewed worldwide by more than 62 million people in its first month, making it the most-watched “limited scripted series” on Netflix. The show is visually compelling: 1960s fashion is one aspect of this, but perhaps the key features are the pace and aspirational tone of the narrative – a young girl/woman, orphaned and facing coming-of-age issues, while striving for the summit in the male-dominated realm of chess. ....

United States , South Africa , Western Cape , South African , Judit Polg , Susan Polg , Boris Spassky , David Bronstein , Magnus Carlsen , Bobby Fischer , Garry Kasparov , Hou Yifan , Francis Galton , David Shenk , Pierre Bourdieu , Wray Mcdermott , Beth Harmon , Paul Morphy , Nona Gaprindashvili , Walter Tevis , International Chess Federation , Woman International Master , Cold War , World Champion , Oxford English Dictionary , Hereditary Genius ,