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Scientist receives $1.37 million grant to advance metabolomics data


Scientist receives $1.37 million grant to advance metabolomics data
The National Institutes of Health (NIH) has awarded University of Massachusetts Amherst biostatistician Raji Balasubramanian a four-year, $1.37 million grant to advance the analysis of data from metabolomics research. These studies examine at the molecular level the links between metabolic action and the risk of chronic health conditions, from heart disease and stroke to breast cancer and other complex disorders.
Balasubramanian, associate professor of biostatistics and epidemiology in the School of Public Health and Health Sciences, will co-lead an interdisciplinary team in the development and application of new statistical models to more effectively mine the expanding base of metabolomics data sources. The other lead investigator is Denise Scholtens, chief of biostatistics and director of the Northwestern University Data Analysis and Coordinating Center. ....

Denise Scholtens , Raji Balasubramanian , Emily Henderson , Northwestern University Data Analysis , University Of Massachusetts Amherst , National Institutes Of Health , Harvard Medical School , School Of Public Health , Health Sciences , National Institutes , Massachusetts Amherst , Public Health , Associate Professor , Breast Cancer , Heart Disease , மறுக்க ஸ்கோல்டென்ஸ் , ராஜி பாலசுப்ரமணியன் , எமிலி ஹென்டர்சன் , வடமேற்கு பல்கலைக்கழகம் தகவல்கள் பகுப்பாய்வு , பல்கலைக்கழகம் ஆஃப் மாசசூசெட்ஸ் மஹேர்ஸ்ட , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , ஹார்வர்ட் மருத்துவ பள்ளி , பள்ளி ஆஃப் பொது ஆரோக்கியம் , ஆரோக்கியம் அறிவியல் , தேசிய நிறுவனங்கள் , மாசசூசெட்ஸ் மஹேர்ஸ்ட ,

Oral Hormone Therapy Women Linked To Heart Disease


Oral Hormone Therapy Women Linked To Heart Disease
by Pooja Shete on 
December 22, 2020 at 7:35 PM
Oral hormone therapy can significantly alter the products of metabolism in post menopausal women. For this research, blood samples from the landmark Women s Health Initiative (WHI) study were examined. This can help explain the disease risks and the protective effects which are linked to different hormone therapy regimen.
The study led by a team of scientists including a University of Massachusetts Amherst biostatistician was published in the
Circulation: Genomic and Precision Medicine.
Raji Balasubramanian, associate professor in the School of Public Health and Health Sciences, whose research connects biostatistics, molecular epidemiology and women s health said, ....

United States , Kathrynm Rexrode , Diseaseshearthealthy Heartlifestyle , Catheterizationheart Attackair , Raji Balasubramanian , Broad Institute , University Of Massachusetts Amherst , Harvard Medical School , School Of Public Health , Women Health Initiative , Broad Institute Of Harvard , Brown University , Health Sciences , Health Initiative , Massachusetts Amherst , Public Health , Hot Flashes , Menopausal Women Targets , Help Reduce Severe Asthma Attacks , Prevent Heart , Diet Lifestyle , Heart Diseasebody Mass Indexreiki , ஒன்றுபட்டது மாநிலங்களில் , ராஜி பாலசுப்ரமணியன் , பரந்த நிறுவனம் , பல்கலைக்கழகம் ஆஃப் மாசசூசெட்ஸ் மஹேர்ஸ்ட ,

Oral hormone therapy changes metabolome of menopausal women, finds study


Oral hormone therapy changes metabolome of menopausal women, finds study
ANI |
Updated: Dec 19, 2020 20:53 IST
Washington [US], December 19 (ANI): In a recent study it has been discovered that hormone therapy can be very useful in significantly altering the metabolome of postmenopausal women.
Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy significantly impacts the metabolome of postmenopausal women, explaining certain disease risks. The study was published in Circulation: Genomic and Precision Medicine.
This finding, which examined blood specimens from the landmark Women s Health Initiative (WHI) study, may help explain the disease risks and protective effects associated with different regimens of hormone therapy. ....

United States , Kathrynm Rexrode , Bryan Sheehan , Raji Balasubramanian , Broad Institute , University Of Massachusetts Amherst , Harvard Medical School , School Of Public Health , Harvard Th Chan School Of Public Health , Broad Institute Of Harvard , Women Health Initiative , Brown University , Health Sciences , Massachusetts Amherst , Health Initiative , Public Health , ஒன்றுபட்டது மாநிலங்களில் , ரியான் ஷீஹான் , ராஜி பாலசுப்ரமணியன் , பரந்த நிறுவனம் , பல்கலைக்கழகம் ஆஃப் மாசசூசெட்ஸ் மஹேர்ஸ்ட , ஹார்வர்ட் மருத்துவ பள்ளி , பள்ளி ஆஃப் பொது ஆரோக்கியம் , ஹார்வர்ட் வது சான் பள்ளி ஆஃப் பொது ஆரோக்கியம் , பரந்த நிறுவனம் ஆஃப் ஹார்வர்ட் , பெண்கள் ஆரோக்கியம் முயற்சி ,

Hormone Therapy-Induced Metabolomic Shift Linked to Coronary Heart Disease in Menopausal Women


Hormone Therapy-Induced Metabolomic Shift Linked to Coronary Heart Disease in Menopausal Women
December 18, 2020
The effect of oral hormone therapy on the metabolome of postmenopausal women is profound. Different hormone therapy regimens result in discordant metabolomic effects that impact the risk for coronary heart disease, reports a study led by Raji Balasubramanian, associate professor in the School of Public Health and Health Sciences, University of Massachusetts, Amherst.
The study, based on the assessment of 481 metabolites in 934 women who participated in the Women’s Health Initiative hormone therapy (WHI-HT) trials, is reported in the article “Metabolomic Effects of Hormone Therapy and Associations with Coronary Heart Disease among Postmenopausal Women,” published in the journal ....

Kathrynm Rexrode , Raji Balasubramanian , Dieta Mediterr , Harvard Medical School , School Of Public Health , University Of Massachusetts , Women Health Initiative , Women Health Initiative Hormone Therapy , Department Of Biostatistics , Division Of Women Health , Health Sciences , Public Health , Health Initiative , Hormone Therapy , Coronary Heart Disease , Postmenopausal Women , Associate Professor , Health Initiative Hormone Therapy , ராஜி பாலசுப்ரமணியன் , ஹார்வர்ட் மருத்துவ பள்ளி , பள்ளி ஆஃப் பொது ஆரோக்கியம் , பல்கலைக்கழகம் ஆஃப் மாசசூசெட்ஸ் , பெண்கள் ஆரோக்கியம் முயற்சி , பெண்கள் ஆரோக்கியம் முயற்சி ஹார்மோன் சிகிச்சை , துறை ஆஃப் உயிரியக்கவியல் , பிரிவு ஆஃப் பெண்கள் ஆரோக்கியம் ,