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Aramburu Castañeda Moero incorporates tax partner

Lima-based law firm Aramburu Castañeda Boero Abogados has announced the incorporation of Mauricio Cavero Blumenfeld as a new partner tax partner. This move brings the firm’s number of partners to five ....

Universidad De Lima , Oscar Boero , Rosa Abogados , Aramburu Casta , Lima Chamber , Cavero Blumenfeld Llosa , யுனிவர்சிடாட் டி லிமா , ரோசா அபகடாஸ் , லிமா அறை ,

A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation


Abstract
To characterize the genetic basis of facial features in Latin Americans, we performed a genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark-based measurements from two-dimensional profile photographs and ~9,000,000 genotyped or imputed single-nucleotide polymorphisms. We detected significant association of 32 traits with at least 1 (and up to 6) of 32 different genomic regions, more than doubling the number of robustly associated face morphology loci reported until now (from 11 to 23). These GWAS hits are strongly enriched in regulatory sequences active specifically during craniofacial development. The associated region in 1p12 includes a tract of archaic adaptive introgression, with a Denisovan haplotype common in Native Americans affecting particularly lip thickness. Among the nine previously unidentified face morphology loci we identified is the VPS13B gene region, and we show that variants in this region also affect midfacial morph ....

United States , Contreras Sieck , M Granados Riveros , Universidad Nacional , J Felisberto Menezes Cavalheiro , Marseille Universit , Souza Jr , Ecole Doctorale , M Ballesteros Romero , D Rogel Diaz , I Jafet Moreno , Excellence Initiative Of Aix , National Natural Science Foundation Of China , University Of Burgundy , Technology Committee Of Shanghai Municipality , Santander Research , Technology Major , Leverhulme Trust , Marseille University , Craniofacial Research , Centre De Calcul Intensif , Technology Of China , Ministry Of Science , Latin Americans , Native Americans , Latin America ,