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AKU wins Rs159 million grant to develop gene-editing therapies for blood disorders


July 1, 2021
Innovative gene-editing therapies for two significant blood disorders, beta thalassemia and sickle cell anaemia, have received a boost with the AKU’s Centre for Regenerative Medicine and Stem Cell Research, CRM, winning a competitive research grant of Rs159.60 million ($1.02 m) to look for a genetic ‘fix’.
Thalassemia and sickle cell disease are genetic disorders, passed down from parent to child, and are common in Pakistan. There are as many as 100,000 transfusion-dependent thalassemia patients in the country. Every year another 5,000 babies are born with the disorder. On the other hand, sickle-cell disease is one of the well-known causes of anaemia in Pakistan. ....

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AKU wins grant to develop gene therapies for blood disorders - Newspaper


KARACHI: Efforts to find less-invasive and more affordable cure for two common genetic disorders beta thalassaemia and sickle cell anaemia have received a boost with Aga Khan University’s research centre recently winning a competitive research grant of Rs159.60 million.
Currently, Pakistan has an estimated 100,000 transfusion-dependent thalassaemia patients with 5,000 babies born with the disease every year.
On the other hand, sickle-cell disease is one of the well-known causes of anaemia in the country.
Doctors and research scientists are aware that mutations in the haemoglobin beta-globin, HBB gene causes both diseases. Patients suffer from a lack of haemoglobin, the protein that carries oxygen from the lungs to the rest of the body; and a lack of oxygen in the body’s tissues can lead to poor growth, organ damage and other health problems. ....

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Gesund bis ins hohe Alter | DO | 15 04 2021 | 16:05

Gesund bis ins hohe Alter | DO | 15 04 2021 | 16:05
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Global Regenerative Medicine Conference, NCRM NICHE with Fujio Cup Quiz (FCQ), E-poster and Edogawa NICHE Prize goes hybrid in 2021

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Global Regenerative Medicine Conference, NCRM NICHE with Fujio Cup Quiz (FCQ), E-poster and Edogawa NICHE Prize goes hybrid in 2021

Global Regenerative Medicine Conference, NCRM NICHE with Fujio Cup Quiz (FCQ), E-poster and Edogawa NICHE Prize goes hybrid in 2021
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