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Burst of Protein Structure Predictions from DeepMind, EMBL


Burst of Protein Structure Predictions from DeepMind, EMBL
July 23, 2021
The tremors that shook the life sciences community last December were mere prelude. Back then, at a biennial protein-prediction competition, an artificial intelligence (AI) tool called AlphaFold delivered an outstanding performance, predicting structures quite as well as X-ray crystallography or cryo-electron microscopy (cryo-EM), the gold standard experimental techniques. Now, AlphaFold has produced an eruption: a release of more than 350,000 protein structure predictions. Besides covering nearly the entire human proteome, the release also extends to biologically significant organisms such as
Escherichia coli, fruit fly, mouse, zebrafish, malaria parasite, and tuberculosis bacteria.
The AlphaFold release was arranged by AlphaFold’s developer, DeepMind, and by DeepMind’s scientific partner, the European Molecular Biology Laboratory (EMBL). Both DeepMind and the EMBL contributed to two art ....

United States , San Francisco , Demis Hassabis , Edith Heard , Ewan Birney , University Of California , European Bioinformatics Institute , University Of Colorado , Drugs For Neglected Diseases Initiative Dndi , European Molecular Biology Laboratory , Centre For Enzyme Innovation , Both Deepmind , Alphafold Protein Structure Database , Critical Assessment , Structure Prediction , Neglected Diseases Initiative , Enzyme Innovation , Human Genome , ஒன்றுபட்டது மாநிலங்களில் , சான் பிரான்சிஸ்கோ , எடித் கேள்விப்பட்டேன் , ய்வந் பிர்னி , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , ஐரோப்பிய உயிர் தகவலியல் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் கொலராடோ , ஐரோப்பிய மூலக்கூறு உயிரியல் ஆய்வகம் ,

This New Database of Over 350,000 Proteins Will Change The Research of Life Itself


This New Database of Over 350,000 Proteins Will Change The Research of Life Itself
PATRICK GALEY, AFP
23 JULY 2021
Scientists on Thursday unveiled the most exhaustive database yet of the proteins that form the building blocks of life, in a breakthrough observers said would fundamentally change biological research .
 
Every cell in every living organism is triggered to perform its function by proteins that deliver constant instructions to maintain health and ward off infection.
Unlike the genome – the complete sequence of human genes that encode cellular life – the human proteome is constantly changing in response to genetic instructions and environmental stimuli.
Understanding how proteins operate – the shape in which they end up, or fold into – within cells has fascinated scientists for decades. ....

Venki Ramakrishnan , John Mcgeehan , Google Deepmind , Cyril Levinthal , Paul Nurse , University Of Portsmouth , European Molecular Biology Laboratory , Francis Crick Institute , Centre For Enzyme Innovation , Enzyme Innovation , பால் செவிலியர் , பல்கலைக்கழகம் ஆஃப் போரதிஸ்மௌத் , ஐரோப்பிய மூலக்கூறு உயிரியல் ஆய்வகம் , பிரான்சிஸ் கிரிக் நிறுவனம் , மையம் க்கு நொதி கண்டுபிடிப்பு , நொதி கண்டுபிடிப்பு ,