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Frontiers | Simultaneous Detection of Ebola Virus and Pathogens Associated With Hemorrhagic Fever by an Oligonucleotide Microarray


Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China
Ebola virus infection causes severe hemorrhagic fever, and its mortality rates varied from 25 to 90% in the previous outbreaks. The highly infectious and lethal nature of this virus highlights the need for reliable and sensitive diagnostic methods to distinguish it from other diseases present with similar clinical symptoms. Based on multiplex polymerase chain reaction (PCR) and oligonucleotide microarray technology, a cost-effective, multipathogen and high-throughput method was developed for simultaneous detection of Ebola virus and other pathogens associated with hemorrhagic fever, including Marburg virus, Lassa fever virus, Junin virus, Machupo virus, Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus, malaria parasite, hantavirus, severe fever with thrombocytopenia syndrome virus, dengue virus, yellow fever virus, Chikungunya virus, influenza A virus, and influenza B virus. This assay ....

South Korea , United States , Democratic Republic Of The Congo , Sierra Leone , El Halas , Chemiluminescent Imager Academy Of Military Medical Sciences , Sangon Biotech Co Ltd , Zhejiang Provincial Center , Technology Program Of Zhejiang Province , Department Of Microbiology , Health Leading Talents Program Of Zhejiang Province , Substrate Millipore Corporation , Aldrich Co , World Health Organization , Development Of China , National Key Research , Family Planning Commission Of Zhejiang Province , Key Disciplinary Of Health , Chinese People Liberation Army , Puruikang Biotech Co Ltd , Academy Of Military Medical Sciences , Academic Committee Of Zhejiang Provincial Center , Shenzhen Puruikang Biotech Co Ltd , Democratic Republic , Rift Valley , Disease Control ,

Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury

Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury
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