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Incyte Announces Results of Phase 3 RUXCOVID Study of Ruxolitinib (Jakafi®) as a Treatment for Patients with COVID-19 Associated Cytokine Storm

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Initial data show that treatment with ruxolitinib plus standard-of-care (SoC) did not prevent complications in patients with COVID-19 associated cytokine storm
Incyte (NASDAQ:INCY) today announced that the Phase 3 RUXCOVID study evaluating the safety and efficacy of ruxolitinib (Jakafi
®), a JAK1/JAK2 inhibitor, plus standard-of-care (SoC) as a treatment for patients 12 years and older with COVID-19 associated cytokine storm did not meet its primary endpoint. Initial data show that there was no reduction in the proportion of patients receiving ruxolitinib plus SoC who experienced severe complications including death, respiratory failure requiring mechanical ventilation or admission to the intensive care unit (ICU) care by Day 29, compared to SoC treatment alone (12.0% vs. 11.8% [OR: 0.91 [95% CI: 0.48-1.73], ....

United States , Steven Stein , Ruxolitinib Jakafi , Exchange Commission , Drug Administration , National Early Warning Score , Incyte Corporation , Chief Medical Officer , Prescribing Information , Placebo Controlled Multi Center Study , Patients With , Cytokine Storm , ஒன்றுபட்டது மாநிலங்களில் , ஸ்டீவன் ஸ்டீன் , பரிமாற்றம் தரகு , தேசிய ஆரம்ப எச்சரிக்கை மதிப்பெண் , தலைமை மருத்துவ அதிகாரி , ப்ரிஸ்க்ரைபிஂக் தகவல் , மருந்துப்போலி கட்டுப்படுத்தப்படுகிறது பல மையம் படிப்பு , நோயாளிகள் உடன் ,

Novartis International AG: Novartis provides update on RUXCOVID study of ruxolitinib for hospitalized patients with COVID-19

Novartis International AG: Novartis provides update on RUXCOVID study of ruxolitinib for hospitalized patients with COVID-19
1
Detailed results will be submitted for publication to support scientific understanding of JAK inhibition in COVID-19 and inform ongoing research
Novartis commitment to address COVID-19 pandemic remains strong with multiple research collaboration initiatives ongoing
Basel, December 14, 2020 - Novartis today announced that the Phase III RUXCOVID study evaluating ruxolitinib on top of standard of care (SoC) therapy compared to SoC treatment alone in patients with COVID-19 did not meet its primary endpoint
1. Initial data show there was no statistically significant reduction in the proportion of patients on ruxolitinib plus SoC therapy who experienced severe complications, including death, respiratory failure requiring mechanical ventilation or admission to the intensive care unit (ICU) by Day 29, compared to SoC alone ....

United States , Isabella Zinck , Eric Althoff , Samir Shah , Thomas Hungerbuehler , Sloan Simpson , John Tsai , Incyte Corporation As Jakafi , Melinda Gates Foundation , Novartis Oncology Communications , Novartis Us External Communications , Innovative Medicines Initiative , Exchange Commission , Head Global Drug Development , National Early Warning Score , Incyte Corporation , Chief Medical Officer , Molecular Partners , Novartis Gene Therapies , Massachusetts Eye , Massachusetts General Hospital , Placebo Controlled Multi Center Study , Patients With , Cytokine Storm , Massachusetts General , ஒன்றுபட்டது மாநிலங்களில் ,

Novartis provides update on RUXCOVID study of ruxolitinib for hospitalized patients with COVID-19 – IT Business Net

Novartis provides update on RUXCOVID study of ruxolitinib for hospitalized patients with COVID-19
Phase III study did not meet its primary endpoint of reducing the number of hospitalized COVID-19 patients who experienced severe complications (death, mechanical ventilation or ICU care)
1
Detailed results will be submitted for publication to support scientific understanding of JAK inhibition in COVID-19 and inform ongoing research
Novartis commitment to address COVID-19 pandemic remains strong with multiple research collaboration initiatives ongoing
Basel, December 14, 2020 Novartis today announced that the Phase III RUXCOVID study evaluating ruxolitinib on top of standard of care (SoC) therapy compared to SoC treatment alone in patients with COVID-19 did not meet its primary endpoint ....

United States , Isabella Zinck , Eric Althoff , Samir Shah , Thomas Hungerbuehler , Sloan Simpson , John Tsai , Incyte Corporation As Jakafi , Melinda Gates Foundation , Novartis Oncology Communications , Novartis Us External Communications , Innovative Medicines Initiative , Exchange Commission , Head Global Drug Development , National Early Warning Score , Incyte Corporation , Chief Medical Officer , Molecular Partners , Novartis Gene Therapies , Massachusetts Eye , Massachusetts General Hospital , Placebo Controlled Multi Center Study , Patients With , Cytokine Storm , Massachusetts General , ஒன்றுபட்டது மாநிலங்களில் ,

Incyte Announces Results of Phase 3 RUXCOVID Study of Ruxolitinib (Jakafi®) as a Treatment for Patients with COVID-19 Associated Cytokine Storm - Press Release

Dec 14, 2020 06:15 UTC
Incyte Announces Results of Phase 3 RUXCOVID Study of Ruxolitinib (Jakafi®) as a Treatment for Patients with COVID-19 Associated Cytokine Storm
WILMINGTON, Del. (Business Wire) Incyte (Nasdaq:INCY) today announced that the Phase 3 RUXCOVID study evaluating the safety and efficacy of ruxolitinib (Jakafi
®), a JAK1/JAK2 inhibitor, plus standard-of-care (SoC) as a treatment for patients 12 years and older with COVID-19 associated cytokine storm did not meet its primary endpoint. Initial data show that there was no reduction in the proportion of patients receiving ruxolitinib plus SoC who experienced severe complications including death, respiratory failure requiring mechanical ventilation or admission to the intensive care unit (ICU) care by Day 29, compared to SoC treatment alone (12.0% vs. 11.8% [OR: 0.91 [95% CI: 0.48-1.73], ....

United States , Catalina Loveman , Steven Stein , Michael Booth , Christine Chiou , Ruxolitinib Jakafi , Nupur Patel , Exchange Commission , Drug Administration , National Early Warning Score , Incyte Corporation , Business Wire , Chief Medical Officer , Prescribing Information , Placebo Controlled Multi Center Study , Patients With , Cytokine Storm , ஒன்றுபட்டது மாநிலங்களில் , கேடலினா லவ்மேன் , ஸ்டீவன் ஸ்டீன் , மைக்கேல் சாவடி , கிறிஸ்டின் சிய , நூபூர் படேல் , பரிமாற்றம் தரகு , தேசிய ஆரம்ப எச்சரிக்கை மதிப்பெண் , வணிக கம்பி ,