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Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis | Critical Care Medicine | JAMA

Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis | Critical Care Medicine | JAMA
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France General , United States , Israel General , City Of , United Kingdom , University Of Chicago , Zuid Holland , British Columbia , East Wing , University College , New South Wales , Kuala Lumpur , Comunidad Autonoma De Cataluna , New Jersey , Srinivas Murthy , Panktid Reid , Niklas Broman , Hierro Majadahonda , Julian Torre Cisneros , Francesca Spiga , Julianpt Higgins , Reuven Pizov , Salud Carlos , Olivier Hermine , Natalie Staplin , Janetv Diaz ,

Coronavirus Disease Weekly News 25April 2021

Coronavirus Disease Weekly News 25April 2021
The news posted last week for the coronavirus 2019-nCoV (aka SARS-CoV-2), which produces COVID-19 disease, has been surveyed and some important articles are summarized here. The articles are more or less organized with general virus news and anecdotes first, then stories from around the US, followed by an increased number of items from other countries around the globe. Economic news related to COVID-19 is found here.
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Summary:
both new Covid cases and US deaths attributed to the virus were lower during the past week. New Covid infections during the week ending April 24th were down 16.3% from during the week ending April 17th, and down 76.7% from the early January peak. US Covid deaths were down 2.0% from the prior week, and down 79.0% from the January peak. New infections in the states that had been leading the early spring surg ....

United States , Israel General , New Castle County , Uttar Pradesh , Madhya Pradesh , North West , South Africa , Papua New Guinea , United Kingdom , Kent County , New Brunswick , New Jersey , Erie County , City Of , Comunidad Autonoma De Cataluna , La Mancha , The Indian , Jammu And Kashmir , Douglas County , New Delhi , University Of Pennsylvania , New York , University Of Cincinnati , Saint Vincent Hospital , Sussex County , South African ,

Experimental drug shows potential against Alzheimer's disease

Credit: Albert Einstein College of Medicine
April 22, 2021 (BRONX, NY) Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer s disease in mice. The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting and recycling them. The study was published online today in the journal
Cell.
Discoveries in mice don t always translate to humans, especially in Alzheimer s disease, said co-study leader Ana Maria Cuervo, M.D., Ph.D., the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases, professor of developmental and molecular biology, and co-director of the Institute for Aging Research at Einstein. But we were encouraged to find in our study that the drop-off in cellular cleaning that contributes to Alzheimer s in mice also occurs in people with the disease, suggesting that our drug may also work in humans. In the 1990s, Dr. Cuerv ....

New York , United States , Comunidad Autonoma De Cataluna , Columbia University , Evripidis Gavathiotis , Joon Choi , Laura Santambrogio , Cristina Clement , Ludovic Collin , David Sulzer , Eugenev Mosharov , Qisheng Xin , Universidad Autonoma , Susmita Kaushik , Yvesr Juste , Daniellel Swaney , Nevan Krogan , Fiona Grueninger , Aurora Scrivo , Roche Pharma , Mathieu Bourdenx , Universitario Ram , Erica Stevenson , Maria Cuervo , Josea Rodriguez Navarro , Antonio Diaz ,

Covid-19: Coronavirus strain first detected in UK now accounts for more than 80% of cases in Spain, but has not overwhelmed hospitals | Society

The strain of the coronavirus that was first detected in England has lived up to the threatening reputation that preceded it. The variant was said to be more contagious, and so it has proven to be. While in January it accounted for less than 2% of new cases, now that figure is in excess of 80%, according to the latest data from the Spanish Health Ministry. But there were also fears that it was more lethal, and would push Spainâs hospitals into a critical condition â something that has not happened so far. This is in contrast to what was seen in the United Kingdom at the start of the year and in France in recent weeks. ....

United Kingdom , North West , South Africa , La Mancha , Comunidad Autonoma De Cataluna , South African , Miguel Cisneros , Universitario Ram , Elena Vanessa Mart , Castillay Le , Quique Bassat , Monica Torres , Juan Carlos Gal , Spanish Health Ministry , European Centre For Disease Control , European Union , Spanish Epidemiological Society , Health Ministry , Spanish Health , Castilla La Mancha , Hospital Universitario Ram , Virgen Del Roc , Hospital Universitario Virgen De La Macarena , European Centre , Disease Control , ஒன்றுபட்டது கிஂக்டம் ,

Carbalive: The CARBALIVE Consortium announces positive results of a Phase 2 equivalent trial of engineered macroporous carbons as a novel treatment for cirrhosis

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The CARBALIVE Consortium announces positive results of a Phase 2 equivalent trial of engineered macroporous carbons as a novel treatment for cirrhosis
Patients treated with orally-administered, non-absorbable engineered carbon of controlled porosity was safe, tolerable and showed trends in improvements in a range of biomarkers of systemic inflammation
The mechanism of this effect is modulation of dysbiosis, gut inflammation and leaky gut that are characteristic of cirrhosis
Planning for pivotal trials to support approval in Europe is now under way
7
th January, 2021 - The
CARBALIVE Consortium( CARBALIVE or the Consortium ) is pleased to announce positive data from the Phase 2 equivalent randomised, double-blind clinical trial of Carbalive, a product candidate for the treatment of patients with decompensated cirrhosis. Carbalive is specifically designed to remove harmful bacterial toxins from the gut, reduce gut inflammation and its permeabilit ....

Rajiv Jalan , Amber Fennell , Universitario Ram , Agustin Albillos , Akaza Bioscience , Zenios Bioscience , Jane Macnaughtan , Kostenloser Wertpapierhandel , University College London , European Union Horizon , Liver Failure Group At University College London , Cajal Institute For Health , Digestive Diseases Group , Carbalive Consortium , Consilium Strategic Communications , European Foundation , Chronic Liver Failure , European Union , Professor Rajiv Jalan , Liver Failure Group , Founding Member , Project Coordinator , Hospital Universitario Ram , Universidad De Alcal , Cajal Institute , Takeda Pharmaceutical ,