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It s just amazing : How this gene therapy helped a blind man start to see
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A blind man regained partial sight after undergoing a gene therapy known as optogenetics and using a pair of specialized goggles, according to a breakthrough case study published in
Nature Medicine.
According to the
New York Times, the human eye generates images when light hits the retina, where photoreceptor cells convert the light into electrical signals they send to neighboring ganglion cells. Those ganglion cells then use the optic nerve to send those signals to the brain, which converts the information into images.
However, roughly two million people worldwide suffer from a collection of progressive, hereditary diseases together called retinitis pigmentosa in which different gene mutations cause photoceptor cells to die off, eventually causing blindness.
Gene therapy trial partially restores eyesight
The full potential of the new therapy to cure blindness has yet to be realised. Keystone / Binsar Bakkara
A blind man has regained part of his sight after a new treatment genetically engineered his eye to produce light-sensitive algae proteins.
This content was published on May 25, 2021 - 11:32
May 25, 2021 - 11:32
swissinfo.ch/mga
The technique, known as optogenetics, was successfully trialled in France with input from the Institute of Molecular and Clinical Ophthalmology Basel (IOB), which is affiliated with the University of Basel.
Cells in the man’s retina were programmed to produce a protein called ChrimsonR, which is sensitive to light. The protein is naturally produced by algae to help them detect light.