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COVID-19 Scan for May 18, 2021


Bamlanivimab cuts hospitalization, deaths in high-risk COVID outpatients
Fewer high-risk outpatients with mild or moderate COVID-19 needed hospitalization or died within 28 days when given bamlanivimab soon after infection compared with their matched peers, finds an observational study yesterday in
Open Forum Infectious Diseases.
University of Pittsburgh researchers compared the outcomes of 232 COVID-19 outpatients given the monoclonal antibody (mAb) from Dec 9, 2020, to Mar 3, 2021, with those of 1,160 coronavirus patients of similar age and health status who didn t receive the drug.
Bamlanivimab reduced the risk of hospitalization and death by 60% and  was associated with a significantly lower risk-adjusted likelihood of hospitalization or death by 28 days (odds ratio [OR], 0.40). Data also showed lower odds of hospitalization or an emergency department (ED) visit without hospitalization in treated patients (OR, 0.54). ....

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News Scan for Apr 21, 2021


Risk factors, mechanisms noted in colistin-resistant Enterobacterales
A study of colistin-resistant Enterobacterales (CORE) isolates from patients in southeast Michigan found that increased age and prior antibiotic receipt were associated with increased risk of CORE colonization or infection, researchers reported today in
Open Forum Infectious Diseases.
In the study, one of the first to provide large-scale colistin resistance data on clinical Enterobacterales isolates in the United States, researchers with the University of Michigan and Case Western Reserve University examined routine clinical isolates obtained in single tertiary health system in Ann Arbor from January 2016 through March 2017.
Patients with CORE isolates were matched 1:1 with patients with colistin-susceptible Enterobacterales (COSE) isolates and uninfected control patients, and multivariable logistics regression was used to compare clinical and microbiologic features. The researchers also conduct ....

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News Scan for Feb 10, 2021


Antibiotic prescribing in telehealth can be appropriate with guidance, study finds
Telemedicine visits in Brazil performed under rigorous adherence to antibiotic stewardship guidelines were associated with appropriate antibiotic prescribing for patients with low-risk conditions, Brazilian and Australian researchers reported yesterday in the
International Journal of Infectious Diseases.
While some studies have suggested that antibiotic prescribing rates for people who consult telemedicine services may be higher than those who have face-to-face visits with providers, most of these studies have not specified the protocols and guidelines accessible to providers or how telemedicine providers should be trained and monitored for antibiotic stewardship.
In this study, researchers assessed antibiotic prescribing at a hospital in Sao Paulo, where all telemedicine providers were required to be trained on international antibiotic stewardship protocols based on the best curren ....

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