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Treatment program at Calgary's Tom Baker Cancer Centre offers 'new hope' for patients with certain blood cancers


 
A new program using CAR T-cell therapy is underway at Calgary s Tom Baker Cancer Centre (TBCC) and is changing the way doctors approach the treatment of certain blood cancers.
Chimeric antigen receptor T-cell (CAR T) therapy uses a person s own immune cells to fight cancer and will now be offered in Alberta to patients with specific kinds of leukemia and non-Hodgkin lymphoma.
CAR T-cell therapy has changed the way we approach the treatment of patients with relapsed/refractory non-Hodgkin lymphoma, said Dr. Mona Shafey, MD, FRCPC, hematologist and director of the Alberta Blood and Marrow Transplant Program. These patients have a very poor prognosis and often die of their disease. The availability of Yescarta gives these patients access to a potentially life-saving treatment. ....

Tyler Shandro , Wendy Beauchesne , Antonella Rizza , Mona Shafey , Martha Kandt , Alberta Cancer Foundation , Calgary Tom Baker Cancer Centre , Alberta Health , Marrow Transplant Program , Tom Baker Cancer Centre , Alberta Blood , Marrow Transplant , Cancer Care Alberta , Alberta Cancer , வெண்டி பேசுசேஷனே , அன்டோனெல்லா ரிஜ்ஜ , ஆல்பர்ட்டா புற்றுநோய் அடித்தளம் , கல்கரி டோம் ரொட்டி சுடுபவர் புற்றுநோய் மையம் , ஆல்பர்ட்டா ஆரோக்கியம் , மஜ்ஜை மாற்று ப்ரோக்ர்யாம் , டோம் ரொட்டி சுடுபவர் புற்றுநோய் மையம் , மஜ்ஜை மாற்று , புற்றுநோய் பராமரிப்பு ஆல்பர்ட்டா , ஆல்பர்ட்டா புற்றுநோய் ,

UC group launches clinical trial using CRISPR to correct sickle cell disease gene defect


UC group launches clinical trial using CRISPR to correct sickle cell disease gene defect
April 1, 2021UCLA
Scientists at UCLA, UC San Francisco and UC Berkeley have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patients’ own blood-forming stem cells.
The trial will combine CRISPR technology developed at the Innovative Genomics Institute a UC Berkeley–UCSF initiative founded by Berkeley’s Nobel Prize–winning scientist Jennifer Doudna with UCLA’s expertise in genetic analysis and cell manufacturing, and the decades-long expertise at UCSF Benioff Children’s Hospital Oakland in cord blood and marrow transplantation and in gene therapy for sickle cell disease. The four-year study will include six adults and three adolescents with severe sickle cell disease. It is planned to begin this summer in Oakland and L ....

United States , Donald Kohn , Mark Walters , Fyodor Urnov , Los Angeles , Jennifer Doudna , California Institute For Regenerative Medicine , Broad Stem Cell Research Center , David Geffen School Of Medicine , Drug Administration , Cure Sickle Cell Initiative , Marrow Transplant Program , Innovative Genomics Institute , Doris Duke Charitable Foundation , National Heart , Nobel Prize , Hospital Oakland , Jordan Family Director , David Geffen School , Stem Cell Research , California Institute , Regenerative Medicine , Blood Institute Led , Doris Duke Charitable , ஒன்றுபட்டது மாநிலங்களில் , டொனால்ட் கோன் ,