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Frontiers | Molecular Phylogenesis and Spatiotemporal Spread of SARS-CoV-2 in Southeast Asia

Frontiers | Molecular Phylogenesis and Spatiotemporal Spread of SARS-CoV-2 in Southeast Asia
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United States , United Kingdom , Indonesia General , Minas Gerais , Forest Hill , Espíto Santo , Northern Samar , Peninsular Malaysia , Malaysia General , New Zealand , Borough Of Bedford , Tinh Bac Giang , Republic Of , New York , East Timor , Van Minh , Han I , Singapore General , Genet Evol , Petaling Tabligh , Abdul Razab , Nat Microbiol , Max Carvalho , Situasi Semasa Jangkitan Penyakit , Kenyataan Akhbar , South East Asia ,

Neanderthal Gene Variants Both Increase and Decrease COVID-19 Risk

Some people become seriously ill when infected with SARS-CoV-2 while others get only mild or no symptoms. In addition to risk factors such as advanced age and diabetes, gene variants also make people more or less sensitive to developing severe COVID-19. A major genetic risk factor is located on chromosome 3 and dramatically increases the risk of respiratory failure and even death. Hugo Zeberg and Svante PÃ¤Ã¤bo at Karolinska Institutet and the Max Planck Institute for Evolutionary Anthropology discovered last year that this risk variant is inherited from Neandertals.
Now the research duo shows that the Neandertals also contributed a protective variant to present-day people. They find that a region on chromosome 12 that reduces the risk of needing intensive care upon infection with the virus by 20 percent is inherited from Neandertals. The genes in this region are called ....

Nordrhein Westfalen , Karolinska Institutet , Hugo Zeberg , Max Planck Institute For Evolutionary Anthropology , Department Of Neuroscience , Max Planck Institute , Evolutionary Anthropology , Ice Age , Proc Natl Acad Sci United , னோற்ர்ேன் வெஸ்ட்ஃபாலன் , துறை ஆஃப் நரம்பியல் , பரிணாம வளர்ச்சி மானுடவியல் , பனி வாழ்நாள் , ப்ராக் நட்டில் அறிவியல் ஒன்றுபட்டது ,

Santhera Announces Corporate Update and Proposal to Strengthen Capital Structure

German
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Pivotal 6-month data readout for vamorolone in Duchenne muscular dystrophy (DMD) expected in the second quarter of 2021
Organization streamlined with a focus on cost savings and progressing vamorolone
Preliminary unaudited result for 2020: net sales CHF 15.0 million; net loss CHF 71.2 million; cash on hand as of December 31, 2020, CHF 12.4 million
Upsized financing from fund managed by Highbridge Capital Management, LLC (an existing investor in the Company), to satisfy liquidity needs through the next value-inflection point
Further strengthening of Santhera’s capital structure through a proposed convertible bond restructuring supported by its largest convertible bondholder representing approx. 32% of total bonds outstanding ....

Switzerland General , United States , Eva Kalias , Dario Eklund , Life Science Alliance , Santhera Pharmaceuticals , Swiss Financial Services Act Fin , Head External Communications , Drug Administration , Santhera Pharmaceuticals Holding , Stifel Nicolaus Europe , European Medicines Agency , Chiesi Group , Highbridge Tactical Credit Master Fund , Highbridge Capital Management , Extraordinary General Meeting , Senior Unsecured Convertible Bonds , Stifel Nicolaus Europe Limited , Priority Review Voucher , Common Technical Document , Bondholder Meeting , Financial Status , Annual Report , Annual General , Bioorg Med Chem , Proc Natl Acad Sci United ,