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Giftanschlag im Hoden: Die fiesen Tricks der Spermien

Giftanschlag im Hoden: Die fiesen Tricks der Spermien
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Bernhard Herrmann , Research Team , Max Planck Institute For Molecular Genetics , Poison Stroke , There Is Exceptions , Max Planck Institute , Molecular Genetics , That Is To Say , Motion Found , Egg Cell , Picture Right , Molecular Genetics That Is To Say , பெர்ன்ஹார்ட் ஹெர்மன் , ஆராய்ச்சி அணி , மூலக்கூறு ஜெநெடிக்ஸ் , முட்டை செல் ,

Some sperm use poison to outrace their competitors

Some sperm use poison to outrace their competitors
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Researchers say that the sperm wining the race to the egg often effectively poisons its competitors on the way. File Photo by Sebastian Kaulitzki/Shutterstock
Feb. 4 (UPI) It turns out that the sperm that win the race to the egg use variants of genetic factors, called distorters, to poison their competitors, according to new research.
Experiments with mouse models suggest a genetic factor called t-haplotype is essential to the production of progressive sperm the ones capable of winning the race
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T-haplotype genes regulate the synthesis of a molecule called RAC1, and the experiments detailed Thursday in the journal PLOS Genetics showed progressive sperm motility requires just the right amount of RAC1. ....

Alexandra Amaral , Bernhard Herrmann , Institute Of Medical Genetics , Max Planck Institute For Molecular Genetics , Max Planck Institute , Molecular Genetics , Medical Genetics , Human Genetics , அலெக்சாண்ட்ரா அமரல் , பெர்ன்ஹார்ட் ஹெர்மன் , நிறுவனம் ஆஃப் மருத்துவ ஜெநெடிக்ஸ் , மூலக்கூறு ஜெநெடிக்ஸ் , மருத்துவ ஜெநெடிக்ஸ் , மனிதன் ஜெநெடிக்ஸ் ,

Some sperms poison their competitors

A genetic factor helps sperm cells outcompete their peers
Competition among sperm cells is fierce – they all want to reach the egg cell first to fertilize it. A research team from Berlin now shows in mice that the ability of sperm to move progressively depends on the protein RAC1. Optimal amounts of active protein improve the competitiveness of individual sperm, whereas aberrant activity can cause male infertility.
In direct competition, t-sperm outcompete their normal peers (+) in the race for the egg cell with genetic tricks, letting them swim in circles.
© MPI f. Molecular Genetics/ Alexandra Amaral
It is literally a race for life when millions of sperm swim towards the egg cells to fertilize them. But does pure luck decide which sperm succeeds? As it turns out, there are differences in competitiveness between individual sperm. In mice, a “selfish” and naturally occurring DNA segment breaks the standard rules of genetic inheritance – ....

Alexandra Amaral , Bernhard Herrmann , Institute Of Medical Genetics At Charit , Max Planck Institute For Molecular Genetics , Max Planck Institute , Molecular Genetics , Medical Genetics , அலெக்சாண்ட்ரா அமரல் , பெர்ன்ஹார்ட் ஹெர்மன் , நிறுவனம் ஆஃப் மருத்துவ ஜெநெடிக்ஸ் இல் அறம் , மூலக்கூறு ஜெநெடிக்ஸ் , மருத்துவ ஜெநெடிக்ஸ் ,

Scientists brave enough to grow a spine

Scientists brave enough to grow a spine
Stem cells self-organise into trunk-like structures.
Comparison of nine-day-old mouse embryo grown in the womb (left) and a trunk-like-structure (right). The neural tube, which eventually makes the spinal cord, is in pink. All other tissues are blue. Credit: J Veenvliet, A Bolondi, MPI f. Mol. Genet
Growing an embryo outside the body may not be that far away.
German scientists report that they have successfully simulated an important phase of the process by growing mouse embryonic cells in a petri dish. The structure was the central trunk, which holds the developing neural tubes that will become the spinal cord. ....

Adriano Bolondi , Jess Veenvliet , Alexander Meissner , Bernhard Herrmann , Germany Max Plank Institute For Molecular Genetics , Max Plank Institute , Molecular Genetics , அலெக்சாண்டர் மைஸ்நர் , பெர்ன்ஹார்ட் ஹெர்மன் , ஜெர்மனி அதிகபட்சம் பிளாங் நிறுவனம் க்கு மூலக்கூறு ஜெநெடிக்ஸ் , அதிகபட்சம் பிளாங் நிறுவனம் , மூலக்கூறு ஜெநெடிக்ஸ் ,