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Latest 'organ-on-a-chip' is a new way to study cancer-related muscle wasting


Latest ‘organ-on-a-chip’ is a new way to study cancer-related muscle wasting
Studying drug effects on human muscles just got easier thanks to a new “muscle-on-a-chip,” developed by a team of researchers from Penn’s School of Engineering and Applied Science and Inha University in Incheon, Korea.
Bioengineering’s Dan Huh and colleagues have developed a number of organ-on-a-chip devices to simulate how human cells grow and perform in their natural environments. Their latest is a muscle-on-a-chip, which carefully captures the directionality of muscle cells as they anchor themselves within the body. (Image: Melissa Pappas).
Muscle tissue is essential to almost all of the body’s organs, however, diseases such as cancer and diabetes can cause muscle tissue degradation or “wasting,” severely decreasing organ function and quality of life. Traditional drug testing for treatment and prevention of muscle wasting is limited through an ....

Mark Mondrinos , Melissa Pappas , Dan Huh , Tulane University , Upenn School Of Engineering , Inha University In Incheon , Applied Science , Inha University , Science Advances , Penn Engineering , மெலிசா பப்பச் , டான் ஹூ , துலேன் பல்கலைக்கழகம் , பென் பள்ளி ஆஃப் பொறியியல் , பயன்படுத்தப்பட்டது அறிவியல் , பென் பொறியியல் ,

Paving the way for new light-powered devices


Paving the way for new light-powered devices
By combining cutting-edge concepts from theoretical physics, researchers from Penn Engineering developed ‘sypersymmetric microlaser arrays’ that are both stable and have high power density.
The field of photonics involves the study of new ways to generate and harness light, akin to how many of the devices used in everyday life run on electric current. While photonic devices have the potential to transform the current technology paradigm through increased speed, efficiency, and information density, their broad application is limited by the size, strength, and stability of the light sources, often lasers, in these devices. ....

Haoqi Zhao , Jieun Yim , Zhifeng Zhang , Tianwei Wu , Nataliam Litchinitser , Ritesh Agarwal , Lliang Feng , Bikashkali Midya , Xingdu Qiao , Zihe Gao , Upenn School Of Engineering , Department Of Materials Science , Duke University , Applied Science , Materials Science , Systems Engineering , ரித்தேஷ் அகர்வால் , லியாங் ஃபெங் , பென் பள்ளி ஆஃப் பொறியியல் , துறை ஆஃப் பொருட்கள் அறிவியல் , டியூக் பல்கலைக்கழகம் , பயன்படுத்தப்பட்டது அறிவியல் , பொருட்கள் அறிவியல் , அமைப்புகள் பொறியியல் ,