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Innovent Announces First Patient Outside China Dosed in the Phase 1 Clinical Trial of Anti-CD47/PD-L1 Bispecific Antibody


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SAN FRANCISCO and SUZHOU, China, Feb. 28, 2021 /PRNewswire/  Innovent Biologics, Inc. ( Innovent ) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of oncology, metabolic, autoimmune and other major diseases, announces that the first patient outside China has been successfully dosed in a Phase 1 clinical trial of the potentially first-in-class recombinant anti-CD47/PD-L1 bispecific antibody (IBI322).
This is a Phase 1a clinical study conducted in the United States to evaluate IBI322 in the treatment of patients with advanced malignancies. The primary objective of the study is to evaluate the safety, tolerability, and initial anti-tumor efficacy of IBI322 in patients with advanced malignancies who have failed standard therapy. ....

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Innovent Announces First Patient Dosed in Phase III Pivotal Trial of IBI310 (CTLA-4) Combined with TYVYT® (sintilimab injection) for the Treatment of First-line Advanced Hepatocellular Carcinoma


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SAN FRANCISCO and SUZHOU, China, Feb. 8, 2021 /PRNewswire/ Innovent Biologics, Inc. ( Innovent ) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of oncology, metabolic, autoimmune and other major diseases, announces that the first patient has been successfully enrolled and dosed in the randomized, open-label, phase III, multicenter clinical study (NCT04720716) evaluating its IBI310 (anti CTLA-4 monoclonal antibody) in combination with TYVYT® (sintilimab injection) for the first-line treatment of patient with advanced hepatocellular carcinoma (HCC). 
In recent years, immune checkpoint inhibitors have brought new hope to HCC patient population with acceptable safety and encouraging efficacy. NCT04720716 is a randomized, open-label, controlled, multicenter phase III study evaluating the efficacy and safety of IBI310 in combination with ....

United States , Hong Kong , Adimab Incyte , Qin Shukui , Eli Lilly , American Society Of Clinical Oncology , Prnewswire Innovent Biologics Inc , Zhongshan Hospital Of Fudan University , Md Anderson Cancer Center , School Of Nanjing University , National Reimbursement Drug List , Head Of Medical Sciences , Professor Fan Jia , Zhongshan Hospital , Fudan University , Professor Qin Shukui , Affiliated Jinling Hospital , Medical School , Vice President , Medical Sciences , Oncology Strategy , Annual American Society , Clinical Oncology , Online Publication , Sintilimab Injection , New Drug Applications ,

Innovent Announces First Patient Dosed in Phase III Pivotal Trial of IBI310 (CTLA-4) Combined with TYVYT® (sintilimab injection) for the Treatment of First-line Advanced Hepatocellular Carcinoma | Antibodies


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SAN FRANCISCO, CA, USA and SUZHOU, China I February 08, 2021 I Innovent Biologics, Inc. ( Innovent ) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of oncology, metabolic, autoimmune and other major diseases, announces that the first patient has been successfully enrolled and dosed in the randomized, open-label, phase III, multicenter clinical study (NCT04720716) evaluating its IBI310 (anti CTLA-4 monoclonal antibody) in combination with TYVYT® (sintilimab injection) for the first-line treatment of patient with advanced hepatocellular carcinoma (HCC). 
In recent years, immune checkpoint inhibitors have brought new hope to HCC patient population with acceptable safety and encouraging efficacy. NCT04720716 is a randomized, open-label, controlled, multicenter phase III study evaluating the efficacy and safety of IBI310 in combination with TYVYT® (sintilimab inject ....

United States , Hong Kong , Adimab Incyte , Qin Shukui , Eli Lilly , American Society Of Clinical Oncology , Zhongshan Hospital Of Fudan University , Md Anderson Cancer Center , School Of Nanjing University , I Innovent Biologics Inc , National Reimbursement Drug List , Head Of Medical Sciences , Innovent Announces First Patient Dosed , First Line Advanced Hepatocellular Carcinoma , Chinai February , Innovent Biologics , Professor Fan Jia , Zhongshan Hospital , Fudan University , Professor Qin Shukui , Affiliated Jinling Hospital , Medical School , Vice President , Medical Sciences , Oncology Strategy , Annual American Society ,