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Preclinical Trials Demonstrate the Efficacy of Nanoparticle-Based Vaccine Written by AZoNanoMay 25 2021 Preclinical studies have demonstrated the effectiveness of an experimental flu vaccine that contains scores of microscopic spherical sacs carrying infection-fighting proteins all through the body. The circle-shaped objects in the image above are cobalt-porphyrin-phospholipid (CoPoP) nanoparticles decorated with flu proteins. Image Credit: University at Buffalo. As explained in a study recently published in the Proceedings of the National Academy of Sciences on May 24 th, 2021, the experimental flu vaccine can: Enhance the effectiveness of seasonal flu vaccines, which generally work 40% to 60% of the time, as per the U.S. Centers for Disease Control and Prevention ....
Nanoparticle based shot could boost efficacy, accelerate production of seasonal flu vaccines Seasonal flu vaccines typically work 40-60% of the time, according to the US Centers for Disease Control and Prevention (CDC). An experimental recombinant protein nanoparticle vaccine that stimulates a strong immune response is hoping to address that inefficiency. Key to the vaccine s success is a liposome the developers created called cobalt-porphyrin-phospholipid, or CoPoP. They are tiny spherical sacs, which are small enough to be considered nanoparticles, and they form the backbone of the vaccine platform. Described in a study published on May 24 by the Proceedings of the National Academy of Science, the experimental vaccine has reportedly proven effective in preclinical studies. ....
Jonathan Lovell, associate professor Department of Biomedical Engineering An experimental flu vaccine consisting of billions of tiny spherical sacs that carry infection-fighting proteins throughout the body has proven effective in preclinical studies. Described in a study published May 24 in the Proceedings of the National Academy of Sciences, the vaccine has the potential to: Improve the effectiveness of seasonal flu vaccines, which typically work 40-60% of the time, according to the U.S. Centers for Disease Control and Prevention. Take less time to produce large quantities because, unlike most seasonal flu vaccines, it is not created in embryonated chicken eggs. Use smaller doses, thereby increasing vaccine supplies, which can be critical given the unpredictable nature of influenza. ....
E-Mail IMAGE: Rose-tinted contact lenses (about 10 mm in diameter) containing gold nanoparticles filter out problematic colors for people with red-green color blindness. view more Credit: Adapted from 2021, DOI: 10.1021/acsnano.0c09657 Imagine seeing the world in muted shades gray sky, gray grass. Some people with color blindness see everything this way, though most can t see specific colors. Tinted glasses can help, but they can t be used to correct blurry vision. And dyed contact lenses currently in development for the condition are potentially harmful and unstable. Now, in ACS Nano, researchers report infusing contact lenses with gold nanoparticles to create a safer way to see colors. ....