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Preclinical Trials Demonstrate the Efficacy of Nanoparticle-Based Vaccine


Preclinical Trials Demonstrate the Efficacy of Nanoparticle-Based Vaccine
Written by AZoNanoMay 25 2021
Preclinical studies have demonstrated the effectiveness of an experimental flu vaccine that contains scores of microscopic spherical sacs carrying infection-fighting proteins all through the body.
The circle-shaped objects in the image above are cobalt-porphyrin-phospholipid (CoPoP) nanoparticles decorated with flu proteins. Image Credit: University at Buffalo.
As explained in a study recently published in the
Proceedings of the National Academy of Sciences on May 24
th, 2021, the experimental flu vaccine can:
Enhance the effectiveness of seasonal flu vaccines, which generally work 40% to 60% of the time, as per the U.S. Centers for Disease Control and Prevention ....

New York , United States , South Korea , South Korean , Matthew Miller , Jonathan Lovell , Bruce Davidson , Research Trainee Fellowship , Mcmaster University , Us Centers For Disease , Us National Institutes Of Health , Canadian Foundation For Innovation , Biomedical Sciences , Canadian Institutes Of Health Research , Study Senior Co , Scripps Research , Physicians Services Inc , Veterans Affairs Western New York Healthcare System , Jacobs School Of Medicine , University At Buffalo , National Academy , Disease Control , Study Senior Author , Associate Professor , Biomedical Engineering , Zachary Sia ,

Nanoparticle based shot could boost efficacy, accelerate production of seasonal flu vaccines


Nanoparticle based shot could boost efficacy, accelerate production of seasonal flu vaccines
Seasonal flu vaccines typically work 40-60% of the time, according to the US Centers for Disease Control and Prevention (CDC). An experimental recombinant protein nanoparticle vaccine that stimulates a strong immune response is hoping to address that inefficiency.
Key to the vaccine s success is a liposome the developers created called cobalt-porphyrin-phospholipid, or CoPoP. They are tiny spherical sacs, which are small enough to be considered nanoparticles, and they form the backbone of the vaccine platform.
Described in a study published on May 24 by the Proceedings of the National Academy of Science, the experimental vaccine has reportedly proven effective in preclinical studies. ....

New York , United States , South Korea , South Korean , Matthew Miller , Jonathan Lovell , Bruce Davidson , Research Trainee Fellowship , Mcmaster University , Canadian Foundation For Innovation , Biomedical Sciences , Canadian Institutes Of Health Research , Scripps Research , University Of Buffalo , Physicians Services Inc , Proceedings Of The National Academy Science , Us National Institutes Of Health , Veterans Affairs Western New York Healthcare System , University At Buffalo , Jacobs School Of Medicine , National Academy , Zachary Sia , Jacobs School , Wei Chiao Huang , Canadian Institutes , Health Research ,