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New Drug Combats Late-stage Prostate Cancer


New Drug Combats Late-stage Prostate Cancer
by Angela Mohan on 
July 12, 2021 at 11:18 AM
New treatment combats late stage prostate cancer by delivering beta radiation directly to tumour cells. It is well tolerated by patients and keeps them alive for longer compared to standard care, as per the phase 3 trial findings.
New approach, targets a molecule called PSMA, which is known to be increased on the surfaces of the tumour cells, destroying them and their surrounding microenvironment.
International team of researchers set out to see whether Lu-PSMA-617 was more effective than standard care and recruited 831 patients with metastatic castration-resistant prostate cancer between June 2018 and October 2019. Patients were randomized to receive the treatment plus standard care or standard care alone. ....

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Obesity increases survival in advanced prostate cancer


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Obese patients with a form of advanced prostate cancer survive longer than overweight and normal weight patients, new research has found.
The study, presented today at the European Association of Urology congress, EAU21, followed more than 1500 patients over three years. Patients classed as obese - with a BMI over 30 - had a ten percent higher survival rate than thinner patients over 36 months.
Although obesity is usually associated with an increased risk of death from many cancers and some other chronic diseases, there is some evidence in a few cancers of a survival advantage for patients with high body mass index. This phenomenon is known as the obesity paradox . ....

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New concept drug hunts down late-stage prostate cancer


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A new class of drug successfully targets treatment-resistant prostate cancers and prolongs the life of patients. The treatment delivers beta radiation directly to tumour cells, is well tolerated by patients and keeps them alive for longer than standard care, found a phase 3 trial to be presented at the European Association of Urology congress, EAU21, today.
Despite progress in medicine in recent years, metastatic castration-resistant prostate cancer remains untreatable and fatal. The new treatment, known as Lu-PSMA-617, takes a new approach, targeting a molecule called PSMA, which is known to be increased on the surfaces of the tumour cells, destroying them and their surrounding microenvironment. ....

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