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COVID pandemic hurt global blood plasma supply at U.S.-Mexico border


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Saul Vazquez used to cross the border from Juárez to El Paso every Wednesday and Friday to donate blood plasma for cash with the kind of commitment typically reserved for a job.
But he hasn’t donated plasma in more than a year because of the ongoing restrictions on “non-essential” border crossings that took effect early in the pandemic. Neither have thousands of other Mexican nationals on whom plasma collection centers depended to donate the antibody-rich material used to make life-saving pharmaceuticals.
The border closure has impacted the plasma market and also hit us economically, those of us who donate,” Vazquez said. ....

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Liminal BioSciences Announces First Subject Dosed in Phase 1 Multiple Ascending Dose Clinical Trial of Fezagepras


Liminal BioSciences Announces First Subject Dosed in Phase 1 Multiple Ascending Dose Clinical Trial of Fezagepras
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LAVAL, QC, and CAMBRIDGE, England, Dec. 15, 2020 /PRNewswire/ - Liminal BioSciences Inc. (Nasdaq: LMNL) ( Liminal BioSciences or the Company ), a clinical-stage biopharmaceutical company, today announced that the first subject has been dosed in the Company s fezagepras Phase 1 multiple ascending dose clinical trial in healthy volunteers.
The new clinical trial is designed to look at more frequent daily dosing (twice and three times daily) of fezagepras up to 2,400mg for a total of 14 days. The clinical trial is a standard placebo-controlled Phase 1 ascending dose design in healthy volunteers. The clinical trial endpoints will include safety, pharmacokinetics, and exploratory biomarkers related to the mechanism of action of fezagepras. The data from this clinical trial will be used to guide se ....

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