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University of North Carolina at Chapel Hill: Breakthrough gene therapies in sight

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Patients with genetic lysosomal storage diseases – particularly children – are living longer because of better treatments. But with promising advances and longer lives comes complications, the loss of eyesight as these rare diseases take their toll over time.
Lysosomal storage diseases are inherited metabolic diseases that are characterized by an abnormal build-up of various toxic materials in the body’s cells as a result of enzyme deficiencies, according to the National Organization for Rare Disorders. With these diseases, patients are missing the mucopolysaccharidosis type 1 (MPS1) gene. Current therapies that allow patients to live longer don’t address corneal clouding caused by these diseases. However, one Carolina-affiliated startup, RainBio, is developing a novel gene therapy for MPSI corneal blindness, giving patients a chance not only for longer lives but better ones. ....

Matt Hirsch , Joanne Kurtzberg , Jude Samulski , Brian Gilger , Joseph Muenzer , Epigenos Bioscience , Fran Martin , School Of Medicine , National Organization For Rare Disorders , Drug Administration , Kickstart Venture Services , Carolina Office Of Technology Commercialization , Office Of Technology Commercialization , Nc State School Of Veterinary Medicine , Nc State University , Gene Therapy Center , National Organization , Therapy Center , Innovate Carolina , Carolina Express License , Carolina Express , Chapel Hill , மேட் ஹர்ஶ் , பிரையன் கில்ஜர் , ஃப்ர்யாந் மார்டின் , பள்ளி ஆஃப் மருந்து ,

Breakthrough gene therapies in sight | UNC-Chapel Hill

Patients with genetic lysosomal storage diseases – particularly children – are living longer because of better treatments. But with promising advances and longer lives comes complications, the loss of eyesight as these rare diseases take their toll over time.
Lysosomal storage diseases are inherited metabolic diseases that are characterized by an abnormal build-up of various toxic materials in the body’s cells as a result of enzyme deficiencies, according to the National Organization for Rare Disorders. With these diseases, patients are missing the mucopolysaccharidosis type 1 (MPS1) gene. Current therapies that allow patients to live longer don’t address corneal clouding caused by these diseases. However, one Carolina-affiliated startup, RainBio, is developing a novel gene therapy for MPSI corneal blindness, giving patients a chance not only for longer lives but better ones. ....

Matt Hirsch , Joanne Kurtzberg , Jude Samulski , Brian Gilger , Joseph Muenzer , Epigenos Bioscience , Fran Martin , School Of Medicine , National Organization For Rare Disorders , Drug Administration , Kickstart Venture Services , Carolina Office Of Technology Commercialization , Office Of Technology Commercialization , Nc State School Of Veterinary Medicine , Nc State University , Gene Therapy Center , National Organization , Therapy Center , Innovate Carolina , Carolina Express License , Carolina Express , Chapel Hill , மேட் ஹர்ஶ் , பிரையன் கில்ஜர் , ஃப்ர்யாந் மார்டின் , பள்ளி ஆஃப் மருந்து ,

Brian Gilger honored as county's top firefighter | News, Sports, Jobs

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Staff photo / R. Michael Semple
Warren firefighter Brian Gilger, center, receives the inaugural Trumbull County Firefighter of the Year award Friday morning at the Parkman Road fire station, where Gilger is stationed. At left is Jim Standohar, marketing director for Servpro, and at right is Ted Snyder, general manager for the Tribune Chronicle. The newspaper and Servpro co-sponsored the award, which is planned to be an annual one.
WARREN Brian Gilger has been around firefighters all his life.
The 25 1/2 years he has worked for the Warren Fire Department are really the second half of his experience because his father, Dave Gilger, worked for the department for 30 years. The elder Gilger during his last three years of service was able to work side-by-side with his son in the department. ....

Ken Nussle , Doug Franklin , Ted Snyder , Dave Gilger , Brian Gilger , Jim Standohar , Warren Fire Department , Trumbull County Firefighter , Tribune Chronicle , Chief Ken Nussle , Chief Bill Monrean , Chronicle General Manager Ted Snyder , Local News , Brian Gilger Honored As Countys Top Firefighter , டக் பிராங்க்ளின் , டெட் ஸ்னைடர் , டேவ் கில்ஜர் , பிரையன் கில்ஜர் , வாரன் தீ துறை , ட்ரம்‌பல் கவுண்டி தீயணைப்பு வீரர் , ட்ரிப்யூன் நாளாகமம் , நாளாகமம் ஜநரல் மேலாளர் டெட் ஸ்னைடர் , உள்ளூர் செய்தி ,