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COVID-19 cases in India underreported by over 20 million, study says


COVID-19 cases in India underreported by over 20 million, study says
Feb 5, 2021
Tests of antibodies, current infections reveal significant spread in India’s southern state
A new study, led by professors at the University of Chicago and Duke University, found that COVID-19 cases in the southern state of Karnataka, India, are nearly 95 times greater than reported. 
The study led by Prof. Anup Malani from the University of Chicago’s Law School and Pritzker School of Medicine, and Prof. Manoj Mohanan from Duke University suggests that 44.1% of the population in rural areas and 53.8% in urban areas in the southern state of Karnataka tested positive for antibodies to COVID-19 by the end of August 2020. ....

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Windtree Appoints Dr. Joseph Soffer to Lead Cardiovascular Clinical Development


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WARRINGTON, Pa., Feb. 1, 2021 /PRNewswire/ Windtree Therapeutics, Inc. (NasdaqCM: WINT), a biotechnology and medical device company focused on advancing multiple late-stage interventions for acute cardiovascular and pulmonary disorders, today announced the appointment of Joseph Soffer, M.D., F.A.C.C., as Executive Director of Clinical Development, effective immediately.
We are thrilled to welcome Joe to lead our cardiovascular clinical development efforts at such an important  time for Windtree, said Dr. Steve Simonson, Chief Medical Officer at Windtree Therapeutics. Joe s expertise in cardiology and substantial experience with drug development in the pharmaceutical industry will be invaluable to our istaroxime program in acute heart failure, including our study in early cardiogenic shock. ....

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Spectrum Health appoints SVP of quality, safety and patient experience - Grand Rapids Business Journal


Grand Rapids Business Journal
Courtesy Spectrum Health
Spectrum Health West Michigan hired Dr. James Moses, M.D., MPH, as senior vice president of quality, safety and patient experience. He will begin his new role in April.
Moses comes to Spectrum Health from Boston University School of Medicine, Boston Medical Center, where he served as chief quality officer and vice president of quality and safety.
At Spectrum Health, Moses will develop and execute strategy, set targets and lead efforts for continuous improvement of quality, safety and patient experience. He will be responsible for integrating quality, safety and patient experience through collaborative leadership and targeted initiatives across Spectrum Health West Michigan. ....

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Dynamic, personalized treatment approach may improve outcomes in gastroesophageal cancers


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A phase 2 clinical trial providing personalized treatments based on the genetic profile of metastatic tumors in gastroesophageal cancers has found that using customized treatment approaches, and adapting them over time as tumors become resistant, led to higher rates of survival compared to historical controls. The final results were published online on Jan. 21 in
Cancer Discovery, a journal of the American Association for Cancer Research.
Advances in technology have made it possible for scientists and physicians to use information about the genetic makeup of a cancerous tumor to inform cancer treatment, but genetic heterogeneity the genetic variation between cancers in different patients and even between tumors within the same patient can make it difficult to determine the most effective targeting strategy for treating individual patients. ....

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