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UroToday - The Global Online Community of Urologists

UroToday - The Global Online Community of Urologists
urotoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from urotoday.com Daily Mail and Mail on Sunday newspapers.

United States , New Zealand , Andrewj Armstrong , Andrew Armstrong , Michaelj Morris , Ian Davis , David Cella , Arun Azad , Brian Rini , Tamim Niazi , Briani Rini , Daniel George , Thomas Powles , Andrea Necchi , Danielj George , Micheal Morris , Ben Tran , Silke Gillessen , Lawrence Mbuagbaw , Cora Sternberg , Lisa Horvath , Coran Sternberg , Yohann Loriot , Cancer Trials Group , European Multidisciplinary Congress On Urological Cancers , Tamer Khashab ,

ASCO GU 2021: TIVO-3: Tivozanib in Patients with Advanced Renal Cell Carcinoma Who Have Progressed After Treatment with Axitinib

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ASCO GU 2021: TIVO-3: Tivozanib in Patients with Advanced Renal Cell Carcinoma Who Have Progressed After Treatment with Axitinib
Published 14 February 2021
(UroToday.com) Tivozanib is a potent and highly selective VEGF receptor tyrosine kinase inhibitor in clinical development for renal cell carcinoma (RCC). Axitinib is also a potent and selective VEGF-receptor inhibitor now commonly part of front-line advanced RCC treatment. In the TIVO-3 trial, tivozanib demonstrated significantly greater progression-free survival (PFS) (hazard ratio [HR] 0.73, 95% confidence interval [CI] 0.56-0.94) and objective response rate (ORR) (15.2% versus 7.5%, p=0.003) versus sorafenib in the intention to treat population, in the subset of patients treated with two prior VEGFR-tyrosine kinase inhibitors (TKI), and in patients treated with a prior VEGFR-TKI and an anti-PD-1 antibody. ....

United States , Zachary Klaassen , Brian Rini , Briani Rini , Vanderbilt Ingram Cancer Center , American Society Of Clinical Oncology , Georgia Cancer Center , Augusta University Medical College Of Georgia , Database Consortium , Clinical Oncology , Cancers Symposium , Urologic Oncologist , Assistant Professor , Medical College , Clinical Oncology Genitourinary Cancers Symposium , ஒன்றுபட்டது மாநிலங்களில் , சக்கரி க்லாஸ்சேங் , பிரையன் ரினி , பிரியாணி ரினி , வாண்டர்பில்ட் இஂக்ரம் புற்றுநோய் மையம் , அமெரிக்கன் சமூகம் ஆஃப் மருத்துவ புற்றுநோயியல் , ஜார்ஜியா புற்றுநோய் மையம் , அகஸ்டா பல்கலைக்கழகம் மருத்துவ கல்லூரி ஆஃப் ஜார்ஜியா , தரவுத்தளம் கூட்டமைப்பு , மருத்துவ புற்றுநோயியல் , புற்றுநோய்கள் சிம்போசியம் ,