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Gilead's Investigational Lenacapavir Demonstrates Sustained Long-Acting Efficacy Through Week 26 in Data Presented at CROI


March 09, 2021


Late-Breaking Preclinical Data Support Further Study of Lenacapavir as a Long-Acting Agent for HIV Prevention –
FOSTER CITY, Calif. (BUSINESS WIRE)
Gilead Sciences, Inc. (Nasdaq: GILD) today presented additional results from the Phase 2/3 CAPELLA trial evaluating the company’s investigational, long-acting HIV-1 capsid inhibitor, lenacapavir, in heavily treatment-experienced people with multi-drug resistant HIV-1 infection. The data build on the positive primary endpoint results announced previously. The new interim efficacy results demonstrate that lenacapavir administered subcutaneously every six months maintained high rates of virologic suppression through 26 weeks in a difficult-to-treat patient population with limited therapy options and high unmet medical need. In this analysis of the ongoing maintenance period of CAPELLA, which evaluated lenacapavir in combination with an optimized background regimen, 73% (n 19/26) of part ....

United States , Foster City , Jacquie Ross , Brian Plummer , Jamesj Rahal Jr , Diana Brainard , Sorana Segal Maurer , Exchange Commission , Gilead Sciences , Gilead On Twitter Sciences , Gilead Public Affairs , Division Of Infectious Diseases At Newyork , Gilead Sciences Inc , Lenacapavir Maintained High Rates , Multi Drug Resistant , Long Acting Agent , Senior Vice President , Virology Therapeutic Area , Breakthrough Therapy Designation , Infectious Diseases , Newyork Presbyterian Queens , Site Principal Investigator , North America , Private Securities Litigation Reform Act , ஒன்றுபட்டது மாநிலங்களில் , வளர்ப்பு நகரம் ,

Reimagining health in the Eastern Cape: As budgets shri...


The Eastern Cape Second Adjustment Budget Speech, delivered on 26 November 2020, mirrored the harsh line taken in the Medium-Term Budget Policy Statement (MTBPS). The total provincial budget has been reduced by R1.8-billion.
Before we explore what this means for socioeconomic rights and entitlements, particularly regarding health, it is useful to recall how provincial budgets are determined and consider what they need to prioritise.
Provinces have limited revenue-raising abilities. The bulk of provincial budgets come from transfers from the national government, with the lion’s share coming from the provincial equitable share. About 40% of all revenue raised by the government is allocated to the provincial equitable share, and a further 7% is allocated to provinces through conditional grants. ....

South Africa , Zweli Mkhize , Eastern Cape Department Of Health , Health Systems Trust District Barometer , National Treasury , Eastern Cape , Eastern Cape Second Adjustment Budget Speech , Medium Term Budget Policy Statement , Multi Drug Resistant , Health Systems Trust District , Dora Nginza , Nelson Mandela Bay , Eastern Cape Department , North West , கிழக்கு கேப் துறை ஆஃப் ஆரோக்கியம் , ஆரோக்கியம் அமைப்புகள் நம்பிக்கை மாவட்டம் காற்றழுத்தமானி , தேசிய கருவூலம் , கிழக்கு கேப் , நடுத்தர கால பட்ஜெட் பாலிஸீ அறிக்கை , பல மருந்து எதிர்ப்பு , ஆரோக்கியம் அமைப்புகள் நம்பிக்கை மாவட்டம் , நெல்சன் மண்டேலா வளைகுடா , கிழக்கு கேப் துறை , வடக்கு மேற்கு ,