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“Expansion Hunter” method can detect DNA errors that lead to repeat expansion diseases Detecting hidden genetic defects by applying an existing method to an existing datasets. Researchers at Radboud university medical center have succeeded: they showed that the Expansion Hunter method can detect errors in the DNA that lead to repeat expansion diseases, such as the movement disorder ataxia. This result provides guidance to fellow researchers worldwide on how to use this method to diagnose patients with genetic disorders. With current diagnostic technology for genetic disorders, it is possible to map all 20,000 genes in our DNA at once. Doctors are increasingly opting for this so-called exome technique: it is widely applicable and increasingly provides molecular diagnoses. The exome technique is particularly suitable for finding simple changes in DNA. ....
Singapore enhances neutralizing antibody testing service Singapore enhances neutralizing antibody testing service 12 April 2021 | News Image credit- prnewswire GenScript Biotech Corporation, Parkway Laboratories and the Diagnostics Development (DxD) Hub announced their collaboration to provide the cPass™ SARS-CoV-2 neutralizing antibody test in Singapore through Parkway s panel of specialist and GP clinics. Neutralizing antibodies are a small percentage of antibodies that bind to sites on the virus and inhibit entry of that virus into the host. Unlike the many COVID-19 lab-based antibody test kits commercially available, cPass™ can detect functional neutralizing antibodies. Traditionally, measuring neutralizing antibodies requires the use of live virus, cells, highly skilled operators, and complex laboratory procedures that require several days in the laboratory to obtain results and limit their widespread use. ....
The University of Sydney, Technovalia and Vax4COVID have announced ethics approval has been granted for an Australian phase one clinical trial of the. ....
Download 6.38 MB Alzheimer s disease is hard to diagnose definitively because it relies on seeing particular pathology in the brain - a collection of a protein called amyloid and another called tau around the nerves. This makes it difficult to test treatments, and to predict the future for people with thinking and memory problems. Guest: ....
University of Calgary and The Hospital for Sick Children (SickKids) researchers have discovered genetic risk factors for OCD that could help pave the way for earlier diagnosis and improved treatment for children and youth. Saliva samples from 5,000 kids were scanned and compared to responses using the Toronto Obsessive-Compulsive Scale. The team identified that those with a genetic variant in the gene PTPRD had a greater risk for obsessive-compulsive traits. Findings published in Translational Psychiatry. ....