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E-Mail IMAGE: DNA replication cycles are tied to the circadian clock, and interruptions can lead to incomplete chromosomes. view more Credit: Image courtesy of Yi Liao. A new study from the University of Chicago has found that the photosynthetic bacterium Synechococcus elongatus uses a circadian clock to precisely time DNA replication, and that interrupting this circadian rhythm prevents replication from completing and leaves chromosomes unfinished overnight. The results, published online on May 10 in Circadian rhythms are the internal 24-hour clock possessed by most organisms on earth, regulating a diversity of biological functions including sleep/wake cycles, hormone production, digestion and body temperature. In humans, disruptions to the circadian rhythm such as working a shift-work job or experiencing frequent jet lag have been associated with an array of health problems, including obesity, cardiovascular and immune dysfunction, mood disor ....
E-Mail A phase 1 clinical trial led by investigators at the University of Chicago Medicine testing the effects of stereotactic body radiotherapy for treating multiple metastases has determined that treatments used for single tumors can also be safely used for treating patients with multiple metastases. The study was run through NRG Oncology and sponsored by the National Cancer Institute. The results were published on April 22 in Cancer is traditionally treated with a combined approach, with clinicians using surgery, chemotherapy and radiation therapy to kill and remove cancerous tumors. Systemic treatments such as chemotherapy often are not enough to stop the cancer s growth. ....
Women had 'alarmingly high rates' of mental health problems during start of the pandemic eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
E-Mail IMAGE: Artist s reconstruction showing the life stages of the fossil lamprey Priscomyzon riniensis. It lived around 360 million years ago in a coastal lagoon in what is now South Africa. Clockwise. view more Credit: Kristen Tietjen A new study out of the University of Chicago, the Canadian Museum of Nature and the Albany Museum challenges a long-held hypothesis that the blind, filter-feeding larvae of modern lampreys are a holdover from the distant past, resembling the ancestors of all living vertebrates, including ourselves. The new fossil discoveries indicate that ancient lamprey hatchlings more closely resembled modern adult lampreys, and were completely unlike their modern larvae counterparts. The results were published on March 10 in ....
E-Mail Nursing homes with the largest proportions of non-White residents experience 3.3 times more COVID-19 deaths than do nursing homes with the largest proportions of White residents, according to a new study from the University of Chicago. The paper, published in JAMA Network Open, suggests that these differences are likely due to nursing home size and the level of coronavirus spread in the local community, reinforcing the inseparability of long-term care facilities from society at large when it comes to bringing the COVID-19 pandemic to heel. Since the start of the pandemic, between 35% and 40% of COVID-19 deaths have been associated with long-term care facilities. Senior author R. Tamara Konetzka, PhD, the Louis Block Professor of Public Health Sciences and the College at UChicago, wanted to bring her 25 years of experience studying nursing homes to ask why these facilities were experiencing such devastation from the coronavirus and if it was possible to predic ....