A team from the University of Washington in the US, examined multiple models recently put forward as potential tools for accurately detecting Covid-19 from chest radiography, otherwise known as chest X-rays.The
A team from the University of Washington in the US, examined multiple models recently put forward as potential tools for accurately detecting Covid-19 from chest radiography, otherwise known as chest X-rays.The
Imbalanced bacterial community in the gums linked to Alzheimer s disease biomarker
Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta a key biomarker for Alzheimer s disease in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer s biomarker called tau.
The study, published in the journal
Alzheimer s & Dementia: Diagnosis, Assessment & Disease Monitoring, adds to the growing evidence of a connection between periodontal disease (gum disease) and Alzheimer s. Periodontal disease which affects 70 percent of adults 65 and older, according to CDC estimates is characterized by chronic and systemic inflammation, with pockets between the teeth and gums enlarging and harboring bacteria.
Study uncovers novel mechanism in rare mutation associated with Alzheimer s
A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer s disease in a new study by investigators at the University of Chicago. The paper, published on April 2 in the
Journal of Experimental Medicine, characterizes a mutation located in a genetic region that was not previously thought be pathogenic, upending assumptions about what kinds of mutations can be associated with Alzheimer s Disease.
Alzheimer s, a neurodegenerative disease that currently affects more than 6 million Americans, has been characterized by the accumulation of Aβ peptide into plaques in the spaces between neurons in the brain. These Aβ peptide are generated when a larger precursor protein, APP, is cleaved into smaller fragments as APP transits through different cellular compartments.