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MD Anderson and Blueprint Medicines Announce Strategic Collaboration to Accelerate BLU-222 Development


Published: Jul 28, 2021
 
HOUSTON and CAMBRIDGE, Mass., July 28, 2021 /PRNewswire/  The University of Texas MD Anderson Cancer Center and Blueprint Medicines Corporation (NASDAQ: BPMC) today announced a three-year strategic research collaboration focused on accelerating development of BLU-222, an investigational precision therapy designed to target cyclin-dependent kinase 2 (CDK2).
The collaboration brings together MD Anderson translational research scientists, the drug development capabilities of MD Anderson s Therapeutics Discovery division and Blueprint Medicines precision therapy pipeline and expertise. The teams seek to characterize the range of cancer types susceptible to treatment with a selective CDK2 inhibitor, advance BLU-222 mono- and combination-therapy strategies with the potential to maximize patient benefit, and identify novel biomarkers that may better predict treatment response and optimize patient selection. ....

United States , United Kingdom , Timothy Heffernan , Fouad Namouni , Blueprint Medicines Corporation , National Cancer Institute , University Of Texas Md Anderson Cancer Center , National Institutes Of Health , Exchange Commission , Md Anderson Translational Research To Advance Therapeutics , Cancer Center , Therapeutics Discovery , Blueprint Medicine , Blueprint Medicines , Translational Research , Advance Therapeutics , Institutional Conflict , Pinterest Management , Monitoring Plan , World Report , National Institutes , Private Securities Litigation Reform Act , Annual Report , Quarterly Report , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் ,

NK cells with bispecific antibody show activity against lymphoma cells


Date Time
NK cells with bispecific antibody show activity against lymphoma cells
Cytokine-activated natural killer (NK) cells derived from donated umbilical cord blood, combined with an investigational bispecific antibody targeting CD16a and CD30 known as AFM13, displayed potent anti-tumor activity against CD30+ lymphoma cells, according to a new preclinical study from researchers at The University of Texas MD Anderson Cancer Center.
The findings were published today in Clinical Cancer Research, a journal of the American Association for Cancer Research. These results led to the launch of a Phase I clinical trial to evaluate the combination of cord blood-derived NK cells (cbNK cells) with AFM13 as an experimental cell-based immunotherapy in patients with CD30+ lymphoma. ....

United States , Katy Rezvani , Pinaki Banerjee , American Association For Cancer Research , University Of Texas Md Anderson Cancer Center , National Institute Of Health , National Cancer Institute , Md Anderson Cord Blood Bank , Clinical Cancer Research , American Association , Stem Cell Transplantation , Cord Blood Bank , Cancer Research , National Institute , Institutional Conflict , Pinterest Management , Md Anderson Cancer Center , University Of Texas , National Cancer Institute , Conflict Of Interest , Cancer Research , Clinical Trial , Umbilical Cord , Cell Therapies , ஒன்றுபட்டது மாநிலங்களில் , பினாக்கி பானர்ஜி ,

Mereo BioPharma and Cancer Focus Fund Announce Partnership


Mereo BioPharma and Cancer Focus Fund Announce Partnership for Phase 1b/2 Study of Etigilimab in Clear Cell Ovarian Cancer
Study to be Conducted at The University of Texas MD Anderson Cancer Center
Mereo BioPharma Group plc; Cancer Focus Fund
LONDON, UNITED KINGDOM
LONDON and REDWOOD CITY, Calif. and HOUSTON, Texas, April 30, 2021 (GLOBE NEWSWIRE) Mereo BioPharma Group plc (NASDAQ: MREO) (“Mereo” or the “Company”), a clinical-stage biopharmaceutical company focused on oncology and rare diseases, and Cancer Focus Fund, LP, a unique venture capital fund established in collaboration with The University of Texas MD Anderson Cancer Center (“MD Anderson”) to provide funding and clinical expertise to advance promising cancer therapies, today announced a partnership to evaluate Mereo’s lead anti-TIGIT therapeutic antibody candidate, etigilimab, in clear cell ovarian cancer, a rare cancer that accounts for approximately 5–10% of ....

United States , City Of , United Kingdom , Barbara Lindheim , Shannon Westin , Christine Fox , Ross Barrett , Lee Roth , Denise Scots Knight , Mereo Biopharma , Cancer Focus Fund , Cancer Focus Fund Contact , Ultragenyx Pharmaceutical Inc , University Of Texas Md Anderson Cancer Center , Mereo Biopharma Group , Feist Weiller Cancer Center Shreveport , Oncologie Inc , Oncxerna Therapeutics Inc , United States Securities Exchange , Partner Of Cancer Focus Fund , Partners For Cancer Focus Fund , Md Anderson Institutional Conflict Of Interest Committee , Biopharma Group , Cancer Center , Gynecologic Oncology , Chief Executive Officer ,