BioAFM viewer software for simulated atomic force microscopy of biomolecules
Abstract: Atomic force microscopy (AFM) allows to obtain images and movies showing proteins at work, however with limited resolution. The developed BioAFMviewer software opens the opportunity to use the enormous amount of available high-resolution protein data to better understand experiments. Within an interactive interface with rich functionality, the BioAFMviewer computationally emulates tip-scanning of any biomolecular structure to generate simulated AFM graphics and movies. They greatly help in the interpretation of e.g., high-speed AFM observations.
Nowadays nanotechnology allows to observe single proteins at work. Under atomic force microscopy (AFM), e.g., their surface can be rapidly scanned, and functional motions monitored, which is of great importance for applications in all fields of Life science. The analysis and interpretation of experimental results remains however challenging because the r
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