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New study shows flies mutant for schizophrenia-associated genes respond well to anti-psychotics


Images of a groups of fruit flies (small black dots) placed in a triangular arena. Normal flies (left triangle) like to be a certain distance apart showing their preference for social space, flies mutants in the schizophrenia-associated Rim gene (right) prefer increased in social distance.
Mutations in the schizophrenia associated cacophony calcium channel gene causes a reduction in calcium signalling in the memory centres of the fly brain called the mushroom body (the two L shaped structures in the images) resulting in memory loss in the flies.
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Press release issued: 19 May 2021
Scientists at Bristol have successfully treated flies displaying behavioural problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics. ....

Jorge Campusano , James Hodge , Sergio Hidalgo , Pontificia Universidad Catolica , Department Of Cellular , School Of Physiology , University Of Bristol , Translational Psychiatry , Molecular Biology , Pontificia Universidad Catolica De Chile , Abnormal Psychology , Branches Of Biology , Circadian Rhythm , Mushroom Bodies , ஜேம்ஸ் ஹாட்ஜ் , செர்ஜியோ ஹிட்யால்கோ , துறை ஆஃப் செல்லுலார் , பள்ளி ஆஃப் உடலியல் , பல்கலைக்கழகம் ஆஃப் பிரிஸ்டல் , மொழிபெயர்ப்பு மனநல மருத்துவம் , மூலக்கூறு உயிரியல் , இயல்பு கடந்த உளவியல் , மனநல மருத்துவம் , கிளைகள் ஆஃப் உயிரியல் , சர்க்காடியன் தாளம் ,

In Major Find, Scientists Catch Nerve Cells Send Information in The 'Wrong' Direction


In Major Find, Scientists Catch Nerve Cells Send Information in The Wrong Direction
19 MAY 2021
The point at which our nerve cells meet to share information was thought to be a one-way street, with electrochemical signals strictly flowing from one neuron s sending axons to the next neuron s receiving dendrites.
 
Now, for the first time, researchers have shown that information can also flow in the opposite direction at the neuron intersection we call a synapse.
Once again, exact measurements have shown that reality is more complex than a simplified model would suggest,  said cellular neuroscientist Peter Jonas from Austria s Institute of Science and Technology (IST). ....

Peter Jonas , Thomas Splettstoesser Wikimedia Commons , David Vandael , Nature Communications , Austria Institute Of Science , Mp Quot , பீட்டர் ஜோனாஸ் , இயற்கை தகவல்தொடர்புகள் , ஆஸ்ட்ரியா நிறுவனம் ஆஃப் அறிவியல் ,

The brain networks underlying imagination

Two components of imagination constructing and evaluating imagined scenarios rely on separate subnetworks in the default mode network, according to research recently published in JNeurosci. ....

Dorsal Default Mode Networks Are Dissociably , Society For Neuroscience , Social Behavioral Science , Memory Cognitive Processes , Perception Awareness , சமூகம் க்கு நரம்பியல் ,