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Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients
Researchers in Israel have conducted a study showing that the use of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine appears to be safe and effective among patients with cancer.
“To our knowledge, this study is the first to prospectively characterize the serologic status, immunogenicity, and safety of the BNT162b2 vaccine in a cohort of patients with solid tumors who are receiving active anticancer therapies,” writes the team from the Rambam Health Care Campus, the Rappaport Faculty of Medicine, and the Technion-Integrated Cancer Center, in Haifa.
While the efficacy and safety profiles of COVID-19 vaccines have previously been demonstrated in phase 3 studies, the team says patients with cancer were not adequately represented in these trials.
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July 8, 2021 • 11:11 am CDT (Precision Vaccinations)
The JAMA Oncology published the results from a cohort study Serologic Status and Toxic Effects of the SARS-CoV-2 BNT162b2 Vaccine in Patients Undergoing Treatment for Cancer.
On July 8, 2021, this Original Investigation concluded by saying, In this cohort study of 223 cancer patients, the SARS-CoV-2 BNT162b2 vaccine (Pfizer-BioNTech, Comrinaty) appeared to be safe and achieve satisfactory serologic status. There was a pronounced lag in antibody production compared with the rate in noncancer controls. However, seroconversion occurred in most patients after the second vaccine dose.
Moreover, future real-world data are warranted to determine the long-term efficacy of the Pfizer-BioNTech vaccine concerning the type of anticancer treatment.
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